scholarly journals A case of multiple evanescent white dot syndrome misdiagnosed as optic neuritis: Differential diagnosis for the neurologist

2016 ◽  
Vol 07 (02) ◽  
pp. 283-285
Author(s):  
Francesco Pellegrini ◽  
Emanuela Interlandi
Keyword(s):  
Differential Diagnosis ◽  
Optic Neuritis ◽  
Acute Onset ◽  
Magnetic Resonance Imaging Scan ◽  
Central Scotoma ◽  
Resonance Imaging ◽  
Local Hospital ◽  
White Dot Syndrome ◽  
Retrobulbar Optic Neuritis ◽  
Uncommon Condition

ABSTRACTA 25-year-old female presented to a local hospital for acute onset of a central scotoma in the left visual field. She was visited by the neurologist, and a diagnosis of left retrobulbar optic neuritis was made. Magnetic resonance imaging scan was normal. Ophthalmic examination revealed a multiple evanescent white dot syndrome. After a description of the case, a brief differential diagnosis between these two entities is made. The neurologist should be aware of this uncommon condition.

Optic Nerve Glioma and Optic Neuritis Mimicking One Another: Case Report

Neurosurgery ◽  
2005 ◽  
Vol 57 (1) ◽  
pp. E190-E190 ◽  
Author(s):  
Luis M. Tumialán ◽  
Sanjay S. Dhall ◽  
Valérie Biousse ◽  
Nancy J. Newman
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optic Nerve ◽  
Magnetic Resonance ◽  
Optic Neuritis ◽  
Visual Loss ◽  
Radiographic Finding ◽  
Acute Onset ◽  
Resonance Imaging ◽  
Optic Nerve Glioma ◽  
The Right

Abstract OBJECTIVE AND IMPORTANCE: The clinical and radiographic presentations of optic nerve gliomas and optic neuritis are for the most part distinct and their diagnoses straightforward. We present two cases illustrating the occasional difficulty one can encounter in distinguishing neoplastic from inflammatory optic neuropathies. CLINICAL PRESENTATION: Patient 1 is a 17-year-old girl who presented with acute onset of pain and rapidly progressive visual loss in the right eye. Patient 2 is a 38-year-old man who presented with painless progressive visual loss in the left eye. INTERVENTION: Patient 1 was initially diagnosed with idiopathic retrobulbar optic neuritis. Interval increase of the optic nerve on magnetic resonance imaging prompted a biopsy of the optic nerve, which revealed a pilocytic astrocytoma. Patient 2 was found to have left optic nerve enhancement most consistent with an optic nerve glioma. Before a biopsy, the patient spontaneously improved without treatment, indicating an inflammatory process. CONCLUSION: Differentiating between optic nerve neoplasm and inflammation may be difficult. On occasion, the classic clinical finding of pain with eye movement and the radiographic finding of enlargement and enhancement of the optic nerve may be misleading. Open biopsy of the optic nerve is indicated only after a completely negative metabolic, infectious, and inflammatory workup; interval increase of the optic nerve on magnetic resonance imaging; and failure of the patient to recover vision.

scholarly journals Demyelinating or hereditary optic neuropathy? Comparison of selected disease entities

2020 ◽  
Vol 20 (2) ◽  
pp. 82-87
Author(s):  
Iwona Rościszewska-Żukowska ◽  
◽  
Halina Bartosik-Psujek ◽  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Optic Neuritis ◽  
Optic Neuropathy ◽  
Leber’S Hereditary Optic Neuropathy ◽  
Leber's Hereditary Optic Neuropathy ◽  
Resonance Imaging ◽  
Retrobulbar Optic Neuritis ◽  
Hereditary Optic Neuropathy

The paper discusses retrobulbar optic neuritis secondary to multiple sclerosis, Leber’s hereditary optic neuropathy, and Leber’s hereditary optic neuropathy with multiple sclerosis-like disease – Harding’s syndrome. Retrobulbar optic neuritis secondary to multiple sclerosis is the most common disease (neuropathy) of the optic nerve in young adults and often the first clinical manifestation of multiple sclerosis. Despite a characteristic triad of symptoms and evident focal demyelination in brain magnetic resonance, misdiagnoses still occur. Leber’s hereditary optic neuropathy (atrophy) is a genetic mitochondrial disease, which manifests as a subacute painless loss of vision, and thus can be mistaken for retrobulbar optic neuritis. The coexistence of hereditary optic neuropathy and Harding’s syndrome is another diagnostic difficulty. All these three conditions, the peak of incidence of which occurs in the second to third decade of life, initially manifest only with visual symptoms due to uni- or bilateral optic neuropathy. Magnetic resonance imaging of the brain may show demyelination, while optical coherence tomography of the fundus may detect thinning of the retinal nerve fibre layers in all these neuropathies. We present clinical differences, as well as variances in retinal optical coherence tomography and magnetic resonance imaging between retrobulbar optic neuritis secondary to multiple sclerosis, Leber’s hereditary optic neuropathy, and Leber’s hereditary optic neuropathy with multiple sclerosis-like disease.

scholarly journals Optic Neuritis in Southeast Asia: a Different Pattern of Disease

1970 ◽  
Vol 12 (4) ◽  
pp. 216-217
Author(s):  
James F. Cullen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Optic Neuritis ◽  
Treatment Trial ◽  
Resonance Imaging ◽  
Optic Disc Swelling ◽  
Retrobulbar Optic Neuritis ◽  
Optic Neuritis Treatment Trial ◽  
Autoimmune Aetiology

This review evaluates a number of recent studies on optic neuritis carried out in Singapore. In Singapore, and probably throughout Asia, the disease is more likely to be of the anterior variety with optic disc swelling, and is sometimes associated with an underlying infective process such as syphilis or tuberculosis, or is of an autoimmune aetiology. Most cases of optic neuritis seen in Singapore are idiopathic; multiple sclerosis is rarely seen in the region, but is likely to be found only in patients with retrobulbar optic neuritis. The 4-year risk for patients in Singapore developing multiple sclerosis is only 9.1% compared with the higher figures reported from the seminal Optic Neuritis Treatment Trial. The usefulness of magnetic resonance imaging in the management of optic neuritis in Singapore is reported.

When It Is Not MS…—Differential Diagnosis of Optic Neuritis and Multifocal Inflammatory Cerebral Lesions in an Adolescent

2017 ◽  
Vol 48 (S 01) ◽  
pp. S1-S45
Author(s):  
T. Deba ◽  
J. Althaus ◽  
O. Schwartz ◽  
J. Penning ◽  
D. Holzinger ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Optic Neuritis ◽  
Cerebral Lesions

The role of magnetic resonance imaging in differential diagnosis of adnexal masses during pregnancy

GYNECOLOGY ◽  
2014 ◽  
Vol 16 (1) ◽  
pp. 69-72
Author(s):  
S.A. Martynov ◽  
◽  
L.V. Adamyan ◽  
E.A. Kulabukhova ◽  
P.V. Uchevatkina ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Adnexal Masses

scholarly journals Impact of the COVID-19 pandemic on neuroimaging scan volumes at a teaching hospital

2021 ◽  
pp. 197140092098866
Author(s):  
Daniel Thomas Ginat ◽  
James Kenniff
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
The United States ◽  
Radiology Department ◽  
Magnetic Resonance Imaging Scan ◽  
Resonance Imaging ◽  
Academic Medical Centre ◽  
Academic Medical ◽  
The Impact

Background The COVID-19 pandemic led to a widespread socioeconomic shutdown, including medical facilities in many parts of the world. The purpose of this study was to assess the impact on neuroimaging utilisation at an academic medical centre in the United States caused by this shutdown. Methods Exam volumes from 1 February 2020 to 11 August 2020 were calculated based on patient location, including outpatient, inpatient and emergency, as well as modality type, including computed tomography and magnetic resonance imaging. 13 March 2020 was designated as the beginning of the shutdown period for the radiology department and 1 May 2020 was designated as the reopening date. The scan volumes during the pre-shutdown, shutdown and post-shutdown periods were compared using t-tests. Results Overall, neuroimaging scan volumes declined significantly by 41% during the shutdown period and returned to 98% of the pre-shutdown period levels after the shutdown, with an estimated 3231 missed scans. Outpatient scan volumes were more greatly affected than inpatient scan volumes, while emergency scan volumes declined the least during the shutdown. In addition, the magnetic resonance imaging scan volumes declined to a greater degree than the computed tomography scan volumes during the shutdown. Conclusion The shutdown from the COVID-19 pandemic had a substantial but transient impact on neuroimaging utilisation overall, with variable magnitude depending on patient location and modality type.

Retrobulbar optic neuritis after pamidronate administration in a patient with a history of cutaneous porphyria

1997 ◽  
Vol 16 (1) ◽  
pp. 93-95 ◽  
Author(s):  
J. M. Des Grottes ◽  
M. Schrooyen ◽  
J. C. Dumon ◽  
J. J. Body
Keyword(s):  
Optic Neuritis ◽  
History Of ◽  
Retrobulbar Optic Neuritis
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