scholarly journals The effect of excision of the parathyroid glands on the morphological picture of submandibular salivary glands in white rats

1967 ◽  
Vol 12 ◽  
pp. 245-252, plates 8-9
Author(s):  
Irena Dzierżykray-Rogalska ◽  
Barbara Obuchowicz
Keyword(s):  
Salivary Glands ◽  
Parathyroid Glands ◽  
White Rats ◽  
Submandibular Salivary Glands ◽  
Morphological Picture

scholarly journals STRUCTURAL REORGANIZATION OF THE RATS’ SUBMANDIBULAR GLANDS ACINI AFTER THE INFLUENCE OF 1% METHACRYLATE

2020 ◽  
Vol 73 (7) ◽  
pp. 1318-1322
Author(s):  
Galyna А. Yeroshenko Yeroshenko ◽  
Larysa Ya. Fedoniuk ◽  
Konstantyn V. Shevchenko ◽  
Denys R. Kramarenko ◽  
Аnastasiia І. Yachmin ◽  
...  
Keyword(s):  
Salivary Glands ◽  
Normal Condition ◽  
Polymeric Materials ◽  
Morphometric Study ◽  
Secretory Cells ◽  
Control Group ◽  
Outer Diameter ◽  
Submandibular Glands ◽  
White Rats ◽  
Submandibular Salivary Glands

Introduction: Polymeric substances, which are used in medicine, can lead to the development of pathological conditions. Therefore, in toxicological evaluation of polymeric materials for medical purposes the primary task is the creation of the appropriate adequate methods of study. The aim: To study the acini of the rats’ submandibular salivary glands in normal condition and after exposure of 1% methacrylate. Material and methods: Were studied 50 white rats during the influence of 1% methacrylate on the mucosa of the oral cavity. Histological sections of the rats’ submandibular salivary glands in normal condition, on day 14 and 30 of experiment were studied using the UMPT – 7 ultramicrotome of Sumy PA “Selmi”. Results and conclusions: The morphometric study has established that in control group the values of the outer diameter of the submandibular glands’ acini, the diameter of the lumen and the height of the acini epithelial cells was 36,27±2,17 μm, 9,47±0,63 μm and 14,18±1,05 μm, respectively. Histological specimens showed that the acini cells had a prominent basophilia of the cytoplasm and the basally located nucleus. Numerous large homogeneous granules were located in the apical pole of the cells. After influence of the 1% methacrylat there is an increase in the activity of secretory cells, which is confirmed by an increase in the height of epitheliocytes by 25.04% and is a compensatory metacrylate reaction. The increase in salivation further leads to complete depletion of the secretory apparatus of the seromucosal cells, which is confirmed by a decrease in the outer and inner diameters with a decrease in the height of the mandibular salivary glands acini cells by 24.40%.

scholarly journals Qualitative ultrastructural analysis of the submandibular salivary glands after administration of khat: in vivo study

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Gamilah Al-Qadhi ◽  
Rabab Mubarak
Keyword(s):  
Salivary Glands ◽  
Arabian Peninsula ◽  
Submandibular Salivary Gland ◽  
Catha Edulis ◽  
Ductal Cells ◽  
Cytoplasmic Vacuoles ◽  
Transmission Electron ◽  
Salivary Gland Cells ◽  
Submandibular Salivary Glands

Abstract Objective Khat (Catha edulis Forssk) plant has been widely chewed for its psychostimulatory effects in the African and Arabian Peninsula, particularly in Yemen. Considering the khat leaves are gradually chewed without swallowing, while its active constituents are extracted into saliva, studying the effect of khat on salivary glands is necessary. This work is an extension of the previously published work that studied the effect of khat extract on the rats' submandibular salivary glands in terms of histological and immunohistochemical evaluations. The current research note aimed to better understand this effect on the ultrastructure of submandibular salivary gland cells by using transmission electron microscope. Results Oral administration of khat extract produced degenerative changes in the secretory and ductal cells of rats' submandibular salivary glands. These changes involved irregular boundaries of variable sized-nuclei, dilated RER, cytoplasmic vacuoles as well as swollen and degenerated mitochondria.

Localization of Chromogranins, Non-neuron-specific Enolase, and Different Forms of Somatostatins in the Submandibular Salivary Glands of Mice

1990 ◽  
Vol 69 (8) ◽  
pp. 1494-1499 ◽  
Author(s):  
A. Letić-Gavrilović ◽  
K. Abe
Keyword(s):  
Growth Factor ◽  
Salivary Glands ◽  
Chromogranin A ◽  
Neuron Specific Enolase ◽  
Biologically Active ◽  
Detection Methods ◽  
Duct System ◽  
Male Mice ◽  
Chromogranin B ◽  
Submandibular Salivary Glands

The localizations of chromogranins A, B, and C, neuron-specific enolase (NSE, γγ-type) and non-NSE (αα-type), and different forms of somatostatins were immunocytochemically identified. The localizations were compared with those of epidermal growth factor (EGF) and nerve growth factor (NGF) in the submandibular salivary glands (SMG) of male mice at five to six weeks of age, with use of a variety of antibodies and the peroxidase-antiperoxidase (PAP) and avidin-biotin complex (ABC) detection methods. In the SMG of male mice, the major chromogranin present was chromogranin A, whereas chromogranins B and C were not detected at these ages by either method. Chromogranin Alike immunoreactivity was located in the granular convoluted tubule (GCT) cells of the SMG, whereas non-NSE immunoreactivity was observed throughout the duct system and in some acinar-associated cells. NSE was not detected in any part of the SMG. The distribution of chromogranin A and somatostatins in the GCT cells was similar to that of EGF and NGF. Our results strongly suggest that chromogranin A and somatostatins, but not chromogranin B or C, may be useful as a means of differentiation of the cells in the duct system of the SMG responsible for the production of biologically-active factors.

Effect of ethanol on prostaglandin E2 receptor in rat submandibular salivary glands

1992 ◽  
Vol 37 (11) ◽  
pp. 869-873 ◽  
Author(s):  
C.Y. Wu-Wang ◽  
S.-L. Wang ◽  
C. Lim ◽  
A. Slomiany ◽  
B.L. Slomiany
Keyword(s):  
Prostaglandin E2 ◽  
Salivary Glands ◽  
Submandibular Salivary Glands ◽  
Prostaglandin E2 Receptor

scholarly journals The determination of specificity, sensitivity and accuracy of core needle biopsy in the diagnosis of parotid and submandibular salivary glands tumors

2019 ◽  
Vol 76 (9) ◽  
pp. 921-928
Author(s):  
Aleksandar Oroz ◽  
Zorana Bokun ◽  
Djordje Antonijevic ◽  
Jasna Jevdjic
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Tumor Tissue ◽  
Submandibular Salivary Gland ◽  
Histopathological Analysis ◽  
Core Needle ◽  
Parotid Salivary Gland ◽  
Submandibular Salivary Glands

Background/Aim. The diagnosis of tumors of salivary glands relies heavily on radiological examination and biopsy of pathological tissue. The aim of this study was to investigate the sensitivity, specificity and accuracy of core needle biopsy in diagnosis of tumors of parotid and submandibular glands. Methods. This study was designed as a crosssectional clinical trial performed between May 2008 and ?ay 2015 at the Department of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center Zemun, Belgrade, Serbia. The examinations included 200 patients among which 100 were diagnosed with tumors of parotid salivary glands and 100 with tumors of submandibular salivary glands. The core needle biopsy was undertaken in all cases where tumor was smaller than 2 cm, far from blood vessels and far from the deep layer of parotid gland. The histopathological analysis was performed to identify histological type of the lesion. Upon performing the surgical procedure and consequently the tumor tissue extirpation, tissue samples obtained were investigated for the definitive diagnosis. Results. The sensitivity of the procedure was 90.9% for parotid salivary gland and 74% for submandibular salivary gland, the specificity was 95.9% for parotid salivary gland and 93% for submandibular salivary gland and the accuracy was 94.7% for parotid salivary gland and 87% for submandibular salivary gland. Based on the histopathological findings of the salivary glands obtained using core needle biopsy of the tumor tissue, it was possible to differentiate between malignant and benign lesions. Conclusion. Current investigation points to the advantages and efficiency of core needle biopsy in diagnosis of tumors of parotid and submandibular salivary glands.

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