scholarly journals Inflammatory syndrome after thoracic aortic endoprothesis implantation associated with cortico-surrenal adenoma

2005 ◽  
Vol 64 (1) ◽  
Author(s):  
Francesco Giallauria ◽  
Anna De Lorenzo ◽  
Athanasio Manakos ◽  
Francesco Pilerci ◽  
Marianna Psaroudaki ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cardiac Rehabilitation ◽  
Thoracic Aorta ◽  
Inflammatory Markers ◽  
Descending Thoracic Aorta ◽  
Rehabilitation Unit ◽  
Postoperative Course ◽  
Inflammatory State ◽  
Inflammatory Syndrome ◽  
Post Implantation

We report a case of a 68-year-old patient, admitted with diagnosis of aneurysm of the descending thoracic aorta to the Department of Cardiac Surgery, where he underwent percutaneous endovascular application of 4 endoprostheses in the descending thoracic aorta. After antibiotic prophylaxis and hemodynamic stabilization, the patient was admitted to the Cardiac Rehabilitation Unit for the management of the of postoperative course and undergo a program of cardiac rehabilitation. Five days following admission and before starting physical training, the patient developed fever associated with neutrophil leukocytosis, strong activation of inflammatory markers and sideropenic anaemia, compatible with post-implantation inflammatory syndrome. Significant hypokaliemia also occurred. Further investigations showed left cortical-surrenal adenoma. The inflammatory state relapsed spontaneously and the patient was discharged with indication to undergo an endocrinologic consultation.

scholarly journals Successful Retrieval of Embolized Amplatzer Septal Occluder from Descending Thoracic Aorta: A Surgical Emergency.

2019 ◽  
Vol 15 (1) ◽  
pp. 37-39
Author(s):  
CM Mosabber Rahman ◽  
Md Alauddin ◽  
Satish Vaidya ◽  
Debasish Das ◽  
Arif Ulla Bhuiyan ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Thoracic Aorta ◽  
Emergency Surgery ◽  
Amplatzer Septal Occluder ◽  
Descending Thoracic Aorta ◽  
Septal Defects ◽  
Cardiac Centre ◽  
Device Embolization ◽  
Successful Retrieval ◽  
Medical University

Amplatzer septal occluder is widely used by the cardiac interventionists as an effective alternative to traditional surgery for atrial septal defects. However, although rare, device may embolize during or after procedure due to several reasons. We report a case of device embolization into the descending thoracic aorta during percutaneous closure of ASD in a 14-year-old girl which was successfully retrieved by emergency surgery at Department of Cardiac Surgery, University Cardiac Centre, Bangabandhu Sheikh Mujib Medical University, Bangladesh. University Heart Journal Vol. 15, No. 1, Jan 2019; 37-39

scholarly journals An Unusual Cause of Anaemia of Chronic Disease: Lisinopril-Induced Chronic Inflammatory State

2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
Toby Eyre ◽  
Victoria Van-Hamel-Parsons ◽  
Lai Mun Wang ◽  
Kathryn A. Hughes ◽  
Timothy J. Littlewood
Keyword(s):  
Chronic Disease ◽  
Systemic Inflammation ◽  
Ace Inhibitors ◽  
Inflammatory Markers ◽  
Eosinophilic Oesophagitis ◽  
Anaemia Of Chronic Disease ◽  
Inflammatory State ◽  
Drug Rash ◽  
Systemic Symptoms ◽  
Inflammatory Syndrome

We report the case of a patient with severe systemic symptoms (weight loss, malaise, and anorexia), eosinophilic oesophagitis, and raised inflammatory markers coinciding with the use of lisinopril. The onset of symptoms occurred after the administration of lisinopril and resolved shortly after cessation of the medication. Despite thorough investigation, no other cause of the systemic inflammation and anaemia of chronic disease was found. “Drug rash with eosinophilia and systemic symptoms” (DRESSs) syndrome describes a potentially serious multiorgan inflammatory response to certain classes of drugs; this includes the use of ACE inhibitors. Although this patient did not meet strict criteria for DRESSs, the subacute inflammatory syndrome with eosinophilic organ infiltration bears similar features. ACE inhibitors should be considered in the differential diagnosis in patients with nonspecific systemic inflammation and anaemia of chronic disease where no other cause is found.

scholarly journals Elderly patient-centered rehabilitation after cardiac surgery

2016 ◽  
Vol 68 (1) ◽  
Author(s):  
Antonio Mazza ◽  
Federica Camera ◽  
Antonella Maestri ◽  
Francesco Longoni ◽  
Anna Patrignani ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Cardiac Surgery ◽  
Cardiac Rehabilitation ◽  
Functional Status ◽  
The Elderly ◽  
Medium Term ◽  
Patient Centered ◽  
Rehabilitation Unit ◽  
Rehabilitation Programs ◽  
Post Surgery

The rate of over-70 year post-surgery patients referred to the Cardiac Rehabilitation Units is increasing. Strategies designed to encourage and facilitate participation in rehabilitation programs in the elderly should be developed. Aim of this paper is to present our elderly-centered program, specifically designed on patient’s needs and frailty, and its short- and medium-term results in 160 consecutive over-70 year patients, admitted in our Cardiac Rehabilitation Unit soon after cardiac surgery. The program was safe, well accepted by the patients, and effective in improving objective and subjective functional status.

Management of thoracic aortic lesions - the future is endovascular

VASA ◽  
2012 ◽  
Vol 41 (3) ◽  
pp. 163-176 ◽  
Author(s):  
Weidenhagen ◽  
Bombien ◽  
Meimarakis ◽  
Geisler ◽  
A. Koeppel
Keyword(s):  
Thoracic Aorta ◽  
Clinical Decision Making ◽  
Treatment Options ◽  
Clinical Decision ◽  
Clinical Results ◽  
Treatment Modalities ◽  
Traumatic Rupture ◽  
Descending Thoracic Aorta ◽  
New Treatment ◽  
Aneurysm Dissection

Open surgical repair of lesions of the descending thoracic aorta, such as aneurysm, dissection and traumatic rupture, has been the “state-of-the-art” treatment for many decades. However, in specialized cardiovascular centers, thoracic endovascular aortic repair and hybrid aortic procedures have been implemented as novel treatment options. The current clinical results show that these procedures can be performed with low morbidity and mortality rates. However, due to a lack of randomized trials, the level of reliability of these new treatment modalities remains a matter of discussion. Clinical decision-making is generally based on the experience of the vascular center as well as on individual factors, such as life expectancy, comorbidity, aneurysm aetiology, aortic diameter and morphology. This article will review and discuss recent publications of open surgical, hybrid thoracic aortic (in case of aortic arch involvement) and endovascular repair in complex pathologies of the descending thoracic aorta.

Penetrating atherosclerotic ulcer aneurysm of the innominate artery

VASA ◽  
2009 ◽  
Vol 38 (3) ◽  
pp. 263-266 ◽  
Author(s):  
Yuan ◽  
Tager
Keyword(s):  
Conservative Treatment ◽  
Thoracic Aorta ◽  
Open Surgery ◽  
Innominate Artery ◽  
Ruptured Aneurysm ◽  
Descending Thoracic Aorta ◽  
Penetrating Atherosclerotic Ulcer ◽  
Descending Aorta

Penetrating atherosclerotic ulcer of the aorta is uncommon, and usually develops in the descending thoracic aorta. Rarely this condition involves the branch vessels of the aorta. We report a case of ruptured aneurysm of the innominate artery resulting from penetrating atherosclerotic ulcer. Open surgery was the treatment of choice for the ruptured aneurysm, while conservative treatment was recommended for the associated penetrating atherosclerotic ulcers of the descending aorta.

scholarly journals In vitro evidence for the involvement of H2S pathway in the effect of clodronate during inflammatory response

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rosangela Montanaro ◽  
Alessio D’Addona ◽  
Andrea Izzo ◽  
Carlo Ruosi ◽  
Vincenzo Brancaleone
Keyword(s):  
Inflammatory Markers ◽  
In Vitro Study ◽  
Inos Expression ◽  
Beneficial Effects ◽  
Tnf Α ◽  
Inflammatory State ◽  
Anti Inflammatory ◽  
Underlying Mechanisms ◽  
Inflammatory Effect

AbstractClodronate is a bisphosphonate agent commonly used as anti-osteoporotic drug. Throughout its use, additional anti-inflammatory and analgesic properties have been reported, although the benefits described in the literature could not solely relate to their inhibition of bone resorption. Thus, the purpose of our in vitro study is to investigate whether there are underlying mechanisms explaining the anti-inflammatory effect of clodronate and possibly involving hydrogen sulphide (H2S). Immortalised fibroblast-like synoviocyte cells (K4IM) were cultured and treated with clodronate in presence of TNF-α. Clodronate significantly modulated iNOS expression elicited by TNF-α. Inflammatory markers induced by TNF-α, including IL-1, IL-6, MCP-1 and RANTES, were also suppressed following administration of clodronate. Furthermore, the reduction in enzymatic biosynthesis of CSE-derived H2S, together with the reduction in CSE expression associated with TNF-α treatment, was reverted by clodronate, thus rescuing endogenous H2S pathway activity. Clodronate displays antinflammatory properties through the modulation of H2S pathway and cytokines levels, thus assuring the control of the inflammatory state. Although further investigation is needed to stress out how clodronate exerts its control on H2S pathway, here we showed for the first the involvement of H2S in the additive beneficial effects observed following clodronate therapy.

scholarly journals Aneurysms of the descending thoracic aorta: Three hundred sixty-six consecutive cases resected without paraplegia

1995 ◽  
Vol 21 (3) ◽  
pp. 385-391 ◽  
Author(s):  
Alain Verdant ◽  
Robert Cossette ◽  
Arthur Pagè ◽  
Richard Baillot ◽  
Leon Dontigny ◽  
...  
Keyword(s):  
Thoracic Aorta ◽  
Descending Thoracic Aorta
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