scholarly journals “Il Piccolo Principe” e la Medicina dell’Invisibile: relazione, organizzazione e prevenzione / "The Little Prince" and the Invisible Medicine: relationship, organization and prevention

2016 ◽  
Vol 65 (3) ◽  
pp. 275-291
Author(s):  
Massimiliano Colucci ◽  
Renzo Pegoraro

In questo articolo, tentiamo di guardare a quattro temi di bioetica attraverso gli occhi del Piccolo Principe: il contesto di fine vita, la relazione medico-paziente, l’etica dell’organizzazione, la prevenzione/precauzione. Useremo un prospettiva che abbiamo chiamato “Medicina dell’Invisibile”, focalizzata sul valore. Il Piccolo Principe ci suggerisce di cercare l’invisibile come un nuovo tipo di “dato clinico” che può aiutare a rendere l’intervento assistenziale più etico ed efficace. Tale invisibile – che è la «cosa importante», la «cosa seria», anche su un piano gnoseologico ed epistemologico – è raggiungibile solo all’interno di una relazione. Perciò, il medico ha bisogno di essere “addomesticato” dal paziente, e il paziente dal medico – ognuno diventando responsabile dell’altro, ognuno diventando se stesso attraverso il dialogo con l’altro. Ma responsabilità significa anche attenzione al futuro, verso minacce alla vita che sono ancora ignote. Infatti, il Piccolo Principe ci insegna che possedere una parte di mondo – il “possesso utile” – implica l’imperativo etico di agire, al fine di salvaguardare la vita. Ma, senza la concretezza di una relazione – impregnata di tempo vissuto, di esperienze condivise, e dell’unicità individuale – non si dà alcun significato né valore. Per questo motivo la Medicina dell’Invisibile ricorda alla Bioetica che «quello che è importante, non lo si vede». ---------- In this paper, we attempt to look at four bioethical issues through the Little Prince’s eyes: the end-life context, the patient-physician relationship, the organization ethics, the prevention/precaution. We will use a perspective we have called “Medicine of the Invisible”, that is value-focused. The Little Prince suggests us to seek the invisible as a new type of ‘clinical data’ which may help to make the healthcare intervention more ethical and effective. Such an invisible – the “thing that is important”, the “matters of consequence”, even on a gnoseological and epistemological level – is attainable only within a relationship. Therefore, the physician needs to be tamed by the patient, and the patient by the physician – each one becoming responsible of the other, each one becoming himself through the dialogue with the other. But responsibility also means attention towards the future, against threats to life that are still unseen and unknown. Indeed, the Little Prince teaches us that owning a part of the world – the “useful possession” – entails the ethical imperative to act, in order to safeguard life. But, without the concreteness of a relationship – saturated with lived time, shared experiences, and individual’s uniqueness – no meaning and no value is given. For this reason the Medicine of Invisible reminds Bioethics that «the thing that is important is the thing that is not seen».

2021 ◽  
pp. 1-12
Author(s):  
Gerasimos M. Tsivgoulis ◽  
Dimitris G. Vachliotis ◽  
Golfo G. Kordopati ◽  
Panayiotis V. Ioannou

Sulfonates are well-known substances with a variety of applications, e.g. as surfactants. On the other hand, bis(sulfonates) bearing hydroxyl or keto group(s) in between the sulfonate groups can be used with or without further modification as starting materials for the preparation of new type of molecules capable to form either complexes or in general supramolecular structures. The synthesis of three hydroxyl-bearing bis(sulfonates), 2-hydroxypropane-1,3-bis(sodium sulfonate) 4, DL-2,3-dihydroxybutane-1,4-bis(sodium sulfonate) 8, and sodium 2,3,4-trihydroxy-1-sulfonate 7 (as by-product) via the Strecker sulfonation are described. Interestingly, under similar conditions, sulfonation of 1,4-dibromo-2,3-butanedione 9 was found to be very complicated and no pure product could be isolated, despite previously reported results on sulfonation of α-halogenated ketones in high yields. There are indications that SO3 2 -  attacks at the carbonyl carbon of 9 followed by rearrangement and expulsion of SO4 2 - . 1,4-dibromo-2,3-butanedione 9, bearing two keto groups next to methylene groups, can potentially exist as enols or in the case of its solution in hydroxylic solvents in the form of hemiketals or geminal diols. This behavior of 9 when is dissolved in CDCl3, CD3OD and D2O was studied by means of UV-Vis, 1H and 13C NMR and the nature of the adducts formed was elucidated.


Development ◽  
1981 ◽  
Vol 66 (1) ◽  
pp. 117-126
Author(s):  
Jane Karlsson ◽  
R. J. Smith

It is a general rule that of two complementary Drosophila imaginal disc fragments, one regenerates and the other duplicates. This paper reports an investigation of an exception to this rule. Duplicating fragments from the periphery of the wing disc which lacked presumptive notum were found to regenerate notum structures during and after duplication. The propensity for this was greatest in fragments lying close to the presumptive notum, with the exception of a fragment confined to the posterior compartment, which did not regenerate notum. Structures were added sequentially, and regeneration stopped once most of the notum was present. These results are not easily explained by the polar coordinate model, which states that regeneration cannot occur from duplicating fragments. Since compartments appear to be involved in this type of regeneration as in others, it is suggested that a new type of model is required, one which permits simultaneous regeneration and duplication, and assigns a major role to compartments.


2012 ◽  
pp. 95-113
Author(s):  
Rita Biancheri

Up to now, in the traditional biomedical paradigm the terms "sex" and "gender" have either been used synonymously and the insertion of gender among the determining elements of conditions of wellbeing/disease has been difficult, and obstructed by disciplinary rigidities that retarded the acceptance of an approach which had already been largely found to be valid in other areas of research. The effected simplification demonstrated its limitations in describing the theme of health; but if, on the one hand, there has been a growing awareness of a subject which can in no way be considered "neutral", on the other hand there continues to be insufficient attention, both in theoretical analysis and in empirical research, given to female differences. The article is intended to support that the sick individual is a person, with his/her genetic heritage, his/her own cultural acquisitions and personal history, and own surrounding life context; but these and similar factors have not traditionally been taken into consideration by official medicine and welfare systems, despite a hoped-for socio-health integration.


2000 ◽  
Vol 13 (1) ◽  
pp. 121-136 ◽  
Author(s):  
Hans-Jörg Rheinberger

The ArgumentIn this essay I will sketch a few instances of how, and a few forms in which, the “invisible” became an epistemic category in the development of the life sciences from the seventeenth century through the end of the nineteenth century. In contrast to most of the other papers in this issue, I do not so much focus on the visualization of various little entities, and the tools and contexts in which a visual representation of these things was realized. I will be more concerned with the basic problem of introducing entities or structures that cannot be seen, as elements of an explanatory strategy. I will try to review the ways in which the invisibility of such entities moved from the unproblematic status of just being too small to be accessible to the naked or even the armed eye, to the problematic status of being invisible in principle and yet being indispensable within a given explanatory framework. The epistemological concern of the paper is thus to sketch the historical process of how the “unseen” became a problem in the modern life sciences. The coming into being of the invisible as a space full of paradoxes is itself the product of a historical development that still awaits proper reconstruction.


Water ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1251 ◽  
Author(s):  
Su-Chin Chen ◽  
Samkele Tfwala ◽  
Tsung-Yuan Wu ◽  
Hsun-Chuan Chan ◽  
Hsien-Ter Chou

A new type of collar, the hooked-collar, was studied through experiments and numerical methods. Tests were conducted using a hooked collar of a width of 1.25b and a height of 0.25b, where b is the bridge-pier width. The hooked-collar efficiency was evaluated by testing different hooked-collar placements within the bridge-pier, which were compared to the bridge-pier without any collar. A double hooked-collar configuration, one placed at the bed level and the other buried 0.25b, was the most efficient at reducing the scour hole. In other cases, a hooked-collar positioned 0.25b above the bed slightly reduced the scour hole and had similar scour patterns when compared to the pier without the hooked-collar. The flow fields along the vertical symmetrical plane in the experiments are also presented. Laboratory experiments and numerical tests show that maximal downflow is highly reduced along with a corresponding decrease in horseshoe vortex strength for the experiments with the hooked-collar, compared to cases without the hooked-collar. The flow fields reveal that the maximum turbulent kinetic energy decreases with the installation of the hooked-collar.


2020 ◽  
Vol 2 (30) ◽  
pp. 116-131
Author(s):  
Александр Харин ◽  

One of the universal and effective methods of business management is value-based management. This method of management, on the one hand, is able to widely use the achievements of the digital economy, and on the other hand, most accurately reflects its specifics. This article discusses models for managing a digital business based on its value. Our research reveals the principles of construction and key features of these models. The result of our work is the conclusion that the future of business process management, as well as the prospects for further socio-economic development of our country, are related to the digitalization of its economy


2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Eka Irma Q Bariah ◽  
Siegfried Berhimpon ◽  
Eunike Louisje Mongi

Edible coating is a new type of packaging made of biopolymer. The advantages of edible coating is enable to protect the food product, the original appearance of the product can be maintained and the product can be eaten as well as environmentally friendly. The study aim was to look at the organoleptic characteristics of fish cake coated with edible coating of carrageenan were given a liquid smoke. The treatments  given were variation of carrageenan concentration i,e. 0%, 1%, 1,5%, 2%, 2,5%, 3%. The experiment was designed using a Completely Randomized Design (CRD). To determine the effect of treatments, the data were tested using organoleptical tests consists of hedonic and texture.The results shown that hedonic test of the appearance and color of the raw sample have significant effect (p>0,05), while the other test showed no significant effect (p>0,05). However, the organoleptical score for taste, smell and texture shown a tendency that the fish cake coated, have  higher score than without coated. Keywords: Edible coating, Carrageenan, Fish cake, Liquid smoke.


Author(s):  
Hiroshi Toda ◽  
Zhong Zhang

We already proved the existence of an orthonormal basis of wavelets having an irrational dilation factor with an infinite number of wavelet shapes, and based on its theory, we proposed an orthonormal basis of wavelets with an arbitrary real dilation factor. In this paper, with the development of these fundamentals, we propose a new type of orthonormal basis of wavelets with customizable frequency bands. Its frequency bands can be freely designed with arbitrary bounds in the frequency domain. For example, we show two types of orthonormal bases of wavelets. One of them has an irrational dilation factor, and the other is designed based on the major scale in just intonation.


1980 ◽  
Vol 42 (1) ◽  
pp. 227-246
Author(s):  
M. Duvert ◽  
D. Gros ◽  
C. Salat

The junctional complex of the intestine of Sagitta setosa has been studied in tissues stained with uranyl acetate or after lanthanum impregnation, and by freeze-cleavage. All types of junctions have been characterized in both perpendicular and tangential planes. From the apex to the base of the cell the following junctions occur in this order: a zonula adhaerens; a septate junction where the septa occur in pairs; a pleated sheet septate junction; and numerous gap junctions of the A-type. From the upper part of the cells inwards to the septate junction, the membranes follow a relatively straight path. In the lower part of the cells the membranes are deeply interdigitating. At the intersection between 3 cells a very different junction is to be observed where small units, periodically disposed, bind the membranes of the 3 adjoining cells. Each unit is composed of 3 short segments which bind the cell membranes to a central ring 16.6 +/− 2.3 nm in outer diameter. The paired septate junction constitutes a new type. Its main features are that the septa are paired and occur in 2 formations, one the ‘loose formation’, with elements between the septa of each pair, and the other, a ‘tight formation’. After lanthanum impregnation, the thickness of each septum is seen to be about 3 nm and the undulation period 12.6 +/− 1.6 nm. On freeze-fractures 10-nm particles are found on crests on the PF face and in furrows on the EF face. The possible significance of this type of junction is discussed. The junctional complex described is analogous to those found in various invertebrate epithelia.


Author(s):  
Helin Alagöz Gessler

This chapter analyses the effects of social media on political communication and the role they play in government-citizen relations by focusing on the Twitter ban phenomenon in Turkey in March 2014. The chapter asks the reasons of government intervention in social media, particularly Twitter. It argues that Twitter makes, on the one hand, a significant contribution to the evolution of political participation as it diversifies the process and methods of political communication. On the other hand, it introduces a new type of security dilemma which encourages governments to consider taking measures against social media to protect their authority.


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