scholarly journals In vitro antifungal susceptibility patterns of Candida albicans from HIV and AIDS patients attending the Nylon Health District Hospital in Douala, Cameroon

2012 ◽  
Vol 3 (1) ◽  
pp. 2 ◽  
Author(s):  
Anna L. Njunda ◽  
Dickson S. Nsagha ◽  
Jules C.N. Assob ◽  
Henri L. Kamga ◽  
Pride Teyim
Keyword(s):  
Candida Albicans ◽  
District Hospital ◽  
Antifungal Susceptibility ◽  
Hiv And Aids ◽  
Health District ◽  
Aids Patients ◽  
In Vitro Antifungal Susceptibility ◽  
Susceptibility Patterns

scholarly journals Molecular Identification and Antifungal Susceptibility Patterns of Candida Species Isolated from Candidemia Patients in Yasuj, Southwestern Iran

2021 ◽  
Vol 14 (7) ◽  
Author(s):  
Shaghayegh Rostami Yasuj ◽  
Maral Gharaghani ◽  
Seyed Sajjad Khoramrooz ◽  
Marjan Salahi ◽  
Ali Keshtkari ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Amphotericin B ◽  
Molecular Identification ◽  
Candida Species ◽  
Antifungal Susceptibility ◽  
Hospitalized Patients ◽  
Susceptibility Tests ◽  
In Vitro Antifungal Susceptibility ◽  
Susceptibility Patterns

Background: Candidemia is the most common systemic infection in hospitalized patients causing high mortality. Hence, the diagnosis of this infection in the early stage with appropriate antifungal therapy is paramount. Objectives: The study aimed at molecular identification of Candida species isolated from candidemia patients and evaluation of the in vitro antifungal susceptibility patterns of these strains to fluconazole, amphotericin B, and caspofungin. Methods: In the present study, 800 hospitalized patients who were suspected to have candidemia were sampled. Candida species were isolated and identified based on morphological characteristics and PCR-sequencing of the ITS1-5.8S-ITS2 region. Antifungal susceptibility tests for fluconazole, amphotericin B, and caspofungin were performed according to the Clinical and Laboratory Standards Institute protocol M27-A3. Also, clinical data were recorded from the patients' records. Results: Twenty-seven patients among the sample of hospitalized patients were found to have candidemia. A total of 33.3% of candidemia patients were treated with amphotericin B, in which case the mortality rate was 14.8%. The majority of patients (59%) were from the neonatal intensive care unit, and premature birth was the most common underlying condition. Candida albicans (n = 18; 66.6%) was the most common species isolated from blood cultures, followed by C. parapsilosis (n = 7; 25.9%), C. pelliculosa (n = 1; 3.7%), and C. tropicalis (n = 1; 3.7%). Only one C. albicans isolate resistant to fluconazole (minimum inhibitory concentration = 32 µg/mL). Conclusions: Generally, C. albicans has been the most frequent causative agent of candidemia. Resistance to antifungal drugs among candidemia agents was rare. Also, the identification of Candida isolates at the species level with in vitro antifungal susceptibility tests helps manage candidemia patients better and decrease the mortality rate among them.

Electrophoretic karyotype and in vitro antifungal susceptibility of Cryptococcus neoformans isolates from AIDS patients

1995 ◽  
Vol 23 (3) ◽  
pp. 99-103 ◽  
Author(s):  
Francesco Barchiesi ◽  
Richard J. Hollis ◽  
Shawn A. Messer ◽  
Giorgio Scalise ◽  
Michael G. Rinaldi ◽  
...  
Keyword(s):  
Cryptococcus Neoformans ◽  
Antifungal Susceptibility ◽  
Electrophoretic Karyotype ◽  
Aids Patients ◽  
In Vitro Antifungal Susceptibility

scholarly journals In vitro antifungal susceptibility patterns of planktonic and sessile Candida kefyr clinical isolates

2017 ◽  
Vol 56 (4) ◽  
pp. 493-500 ◽  
Author(s):  
Fruzsina Nagy ◽  
Aliz Bozó ◽  
Zoltán Tóth ◽  
Lajos Daróczi ◽  
László Majoros ◽  
...  
Keyword(s):  
Antifungal Susceptibility ◽  
Clinical Isolates ◽  
Candida Kefyr ◽  
In Vitro Antifungal Susceptibility ◽  
Susceptibility Patterns

scholarly journals Species Distribution and In Vitro Antifungal Susceptibility Patterns of 75 Clinical Isolates of Fusarium spp. from Northern Italy

2008 ◽  
Vol 52 (7) ◽  
pp. 2683-2685 ◽  
Author(s):  
Anna Maria Tortorano ◽  
Anna Prigitano ◽  
Giovanna Dho ◽  
Maria Carmela Esposto ◽  
Claudia Gianni ◽  
...  
Keyword(s):  
Species Distribution ◽  
Fusarium Verticillioides ◽  
Antifungal Susceptibility ◽  
Northern Italy ◽  
Molecular Methods ◽  
Clinical Isolates ◽  
Fusarium Spp ◽  
In Vitro Antifungal Susceptibility ◽  
Susceptibility Patterns

ABSTRACT Fusarium isolates from 75 Italian patients were identified by molecular methods, and their susceptibilities to antifungals were tested in vitro. Fusarium verticillioides was the species most frequently isolated from deep-seated infections, and F. solani was the species most frequently isolated from superficial infections. F. solani isolates showed high azole MICs, while F. verticillioides isolates showed low posaconazole MICs.

Sign in / Sign up

Export Citation Format

Share Document