scholarly journals Unilateral demodicidosis of face mimicking Hansens disease

2016 ◽  
Vol 8 (1) ◽  
Author(s):  
Deepak Vashisht ◽  
Jatinder Singh ◽  
Sukriti Baveja ◽  
Rohit Tiwari ◽  
Anuj Bhatnagar

Demodicosis is a common parasitic infection of the hair follicles and the pilosebaceous unit by the <em>Demodex mites viz. Demodex</em> folliculorum and<em> Demodex brevis.</em> Infection by this parasite is common among immunocompromised and elderly. We report a case of facial Demodicosis which presented like atypical rosacea with a gradually progressing swelling and redness on right side of face which was initially diagnosed as a case of Hansen’s disease. Skin biopsy revealed follicular dilatation with presence of Demodex mite along with intense perifollicular lymphomononuclear infiltrate. Patient was treated with oral tab Ivermectin 12 mg stat along with topical gel metronidazole twice daily to which he responded favourably.

2020 ◽  
Vol 3 (2) ◽  
pp. 108-121
Author(s):  
Sara Królik ◽  
Agnieszka Muth ◽  
Adriana Polańska ◽  
Ryszard Żaba ◽  
Zygmunt Adamski ◽  
...  

Introduction. Human Demodex mites (Demodex folliculorum and Demodex brevis) are ectoparasites living inside the sebaceous glands and hair follicles. In most people, their presence is of no consequence. However, several conditions or various external factors might contribute to pathological Demodex infestation resulting in demodicosis. Many different cutaneous diseases can resemble demodicosis leading to misdiagnosis.Aim. This paper aims to present information about demodicosis and provides a clear clinical portrait of demodicosis in order to distinguish it from other mimicking inflammatory dermatoses. Material and Methods. The literature search was conducted in the English and Polish language via the PubMed database and Main Medical Library. The articles regarding Demodex infestation were selected. Results. There is some evidence about the role of Demodex in the development of rosacea, blepharitis and clinical correlation between them.Conclusions. More attention should be drawn to Demodex as it plays a significant role in the development of various clinical entities in both dermatology and ophthalmology.


2013 ◽  
Vol 75 (4) ◽  
pp. 326-330
Author(s):  
Ikumi NAKAMURA ◽  
Sayaka YAMAGUCHI ◽  
Yoshiyuki KARIYA ◽  
Shigetaka MATORI ◽  
Kiyohito TAIRA ◽  
...  

2003 ◽  
Vol 65 (4) ◽  
pp. 355-358
Author(s):  
Mayumi UJIHARA ◽  
Maki YOKOGAWA ◽  
Hajime KODAMA

2020 ◽  
Vol 26 (27) ◽  
pp. 3251-3268
Author(s):  
Shweta Ramkar ◽  
Abhishek K. Sah ◽  
Nagendra Bhuwane ◽  
Ishwari Choudhary ◽  
Narayan Hemnani ◽  
...  

The pilosebaceous unit is the triad comprising of hair follicle, arrector pilli muscle, and sebaceous gland. Drug delivery to and through the hair follicles has garnered much attention of the researchers and the hair follicles represent an attractive target site via topical applications. They are bordered by capillaries and antigenpresenting cells, connected to the sebaceous glands and the bulge region of the hair follicle anchors the stem cells. The nano lipid carriers have the propensity to penetrate through the skin via transcellular route, intracellular route and follicular route. It has been established that nano lipid carriers have the potential for follicular drug delivery and provide some advantages over conventional pathways, including improved bioavailability, enhanced penetration depth, fast transport into the skin, tissue targeting and form a drug reservoir for prolonged release. This review describes the pilosebaceous unit (PSU) and related diseases and the recent lipid-based nanotechnology approaches for drug delivery to the follicular unit as well as related issues. Different types of nano lipid carriers, including ethosomes, liposomes, nanoparticles, solid lipid nanoparticles (SLNs), and nano lipid carriers (NLCs) have been reported for follicular drug delivery. Targeted drug delivery with nano-lipid carriers has the potential to augment the efficacy of drugs/bioactives to treat diseases of PSU. This review systematically introduces the activities of different formulations and the use of nano lipid carriers in treating PSU related disorders like alopecia, acne, and hirsutism.


2014 ◽  
Vol 109 (2) ◽  
pp. 182-188 ◽  
Author(s):  
Sérgio Ricardo Fernandes Araújo ◽  
Sarra Elisabeth Jamieson ◽  
Kathryn Margaret Dupnik ◽  
Glória Regina Monteiro ◽  
Maurício Lisboa Nobre ◽  
...  

2013 ◽  
Vol 3 (1) ◽  
pp. 36 ◽  
Author(s):  
Padmamalini Mahendradas ◽  
Kavitha Avadhani ◽  
Sarika Ramachandran ◽  
Sahana Srinivas ◽  
Madhavi Naik ◽  
...  

1994 ◽  
Vol 87 (3) ◽  
pp. 211-221 ◽  
Author(s):  
G. Chandra Sekhar ◽  
G. Vance ◽  
S. Otton ◽  
S. Vinay Kumar ◽  
J. N. A. Stanley ◽  
...  

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