scholarly journals Peripheral giant cell granuloma recurring as an exclusively intra-osseous lesion: An unusual clinical presentation

2018 ◽  
Author(s):  
Kedar Vaidya ◽  
Gargi S. Sarode ◽  
Sachin C. Sarode ◽  
Barnali Majumdar ◽  
Shankargouda Patil
Keyword(s):  
Giant Cell ◽  
Present Report ◽  
Treatment Plan ◽  
Surgical Excision ◽  
Giant Cell Granuloma ◽  
Unique Case ◽  
Peripheral Giant Cell Granuloma ◽  
Multiple Regions ◽  
Central Lesions ◽  
Rule Out

Giant cell lesions of the jaws represent distinctive clinico-pathological spectrum. They manifest as peripheral and central lesions, occurring as solitary growths to involving multiple regions of the jaw. The present report presents a unique case of giant cell lesions of the jaws, wherein a peripheral giant cell granuloma recurred exclusively as a central giant cell lesion in a young patient. The recurrence was noted after a time-span of 3 years since the diagnosis and surgical excision of the peripheral lesion. Biochemical investigations were advised to rule out the possibility of hyperparathyroidism. Following a confirmed diagnosis of central giant cell granuloma, not associated with any other systemic conditions, an apt treatment plan was devised for an early rehabilitation of the patient.

scholarly journals Management of recurrent peripheral giant cell granuloma -a case report

2016 ◽  
Vol 4 (2) ◽  
pp. 138
Author(s):  
Santha Kumari Prathypaty ◽  
Santhi Priya Potharaju ◽  
Ravi Kanth Chintala ◽  
Satheesh Kumar Guvvala ◽  
Jai Krishna Srikanth Kolliboyana
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Chronic Infection ◽  
Tooth Extraction ◽  
Benign Tumor ◽  
Surgical Excision ◽  
Giant Cell Granuloma ◽  
Complete Excision ◽  
Periodontal Membrane ◽  
Peripheral Giant Cell Granuloma

Peripheral giant cell granuloma (PGCG) which is also called as Giant cell Epulis is one of the most common reactive hyperplastic lesions of the oral cavity. There are various etiologies relating PGCG which include local irritation, trauma, tooth extraction, irregular restorations, plaque, calculus, chronic infection & impacted food. One important other etiology of this benign tumor is its origin from periosteum or periodontal membrane. Excision of the lesion completely along with extraction of involved tooth is the option of treatment to prevent recurrence of the lesion in some cases. This case report describes the recurrence of the Peripheral giant cell granuloma even after complete excision in 3 months.Management of recurrent Peripheral giant cell granuloma by surgical excision of the lesion was carried out along with extraction of the associated tooth and curettage of the bone walls. Profuse bleeding after tooth extraction was managed by gel-spun. Periodic recalls doesn’t show any recurrence until one month.

Aggressive behavior of peripheral giant cell granuloma: A case report

2021 ◽  
Vol 2 (4) ◽  
Author(s):  
Nadia Fathy Hassabou ◽  
◽  
Yasmine Alaa Eldin ◽  
Amina Fouad Farag ◽  
◽  
...  
Keyword(s):  
Giant Cell ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Multinucleated Giant Cells ◽  
Periodontal Membrane ◽  
Neoplastic Lesion ◽  
Peripheral Giant Cell Granuloma ◽  
Chronic Trauma

Background: Peripheral Giant Cell Granuloma (PGCG) considered one of the commonest oral giant cell lesions and gingival epulis. It is probably a non neoplastic lesion but rather reactive in nature which originates from the periodontal membrane or the periosteum as a reaction to chronic trauma or local irritation. This article reports a case of PGCG in a 6 years old male patient complaining of massive gingival swelling associated with looseness of related teeth which is highly unlikely to occur with such lesions, that may lead to misdiagnosis. Material and method: Surgical excision followed by histopathological examination was performed and confirmed using CD34 and CD45 for detection and confirming the origin of multinucleated giant cells (MNGCs). Results: Immunopositivity for CD34 was demonstrated only as cytoplasmic reaction of endothelial cells lining blood vessels while negative reaction was observed in MNGCs or in stromal mononuclear cell. Moreover, cytoplasmic immunoreactivity for CD45 was revealed in MNGCs and few stromal cells. Conclusion: Correlating clinical, radiographic and histopathologic examination reaching definite and early diagnosis is mandatory for management of such lesions thus eliminating potential risk of damaging to adjacent hard tissue structures. Keywords: Peripheral giant cell granuloma; multinucleated giant cells; CD34; CD45.

Peripheral giant cell granuloma: A case report and review

2017 ◽  
Vol 4 (1) ◽  
pp. 1-3
Author(s):  
Tejavathi Nagaraj ◽  
Lakshmi Balraj ◽  
Pooja Sinha ◽  
Sreelakshmi Narayanan
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma

scholarly journals Massive peripheral giant cell granuloma associated with pregnancy

2016 ◽  
Author(s):  
Vikas Jain
Keyword(s):  
Oral Cavity ◽  
Giant Cell ◽  
Ovarian Hormones ◽  
Contributory Factor ◽  
Hormonal Changes ◽  
Giant Cell Granuloma ◽  
Young Females ◽  
Peripheral Giant Cell Granuloma ◽  
Nodular Lesions

Peripheral giant cell granuloma (PGCG) is a relatively Common reactive exophytic lesion of the oral cavity. The influence of hormones has been suggested as contributory factor in PGCG development and predominance of these lesions in young females as well as some previously reported pregnancy related cases support this belief. It has been observed that majority of lesions present in the 4th decade of life, when hormonal changes are more pronounced. Cailluette and Mattar in their study found that peripheral giant cell granuloma are under the influence of the ovarian hormones. However Chambers and Spector suggested peripheral giant cell granuloma to be enhanced by pregnancy rather than being pregnancy dependent. The responsiveness of gingiva to these hormones along with the immunosuppressive actions of the hormones contributes to the growth of the lesion. Clinically, PGCGs may present as polypoid or nodular lesions, predominantly bluish red with a smooth shiny or mamillated surface.This poster will review the literature available on the association of Massive Peripheral Giant Cell Granuloma With Pregnancy with focus on possible causes of PGCG during pregnancy.

scholarly journals Coexistence of hyperparathyroidism and peripheral giant cell granuloma of the jaw: A rare case report

2020 ◽  
Vol 9 (6) ◽  
pp. 3142 ◽  
Author(s):  
Naina Pattnaik ◽  
JagadishP Rajguru ◽  
SamarjeetJ Pattanaik ◽  
Debajyoti Bardhan ◽  
Bikash Nayak ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Rare Case ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma ◽  
Rare Case Report

scholarly journals Reactive Hyperplastic Lesions of the Gingiva: A Retrospective Study of 260 Cases

2012 ◽  
Vol 3 (2) ◽  
pp. 126-130 ◽  
Author(s):  
Sangeetha Ramu ◽  
Charlotte Rodrigues
Keyword(s):  
Retrospective Study ◽  
Giant Cell ◽  
Pyogenic Granuloma ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Multicenter Studies ◽  
Age And Gender ◽  
Peripheral Giant Cell Granuloma ◽  
The Mean ◽  
And Gender

ABSTRACT Objectives The purpose of the study was to analyze the frequency and distribution of gingival lesions in MR Ambedkar Dental College, Bengaluru. Materials and methods The material included the biopsies of all localized reactive hyperplastic lesions (LRHL) of the gingiva stored in the department's database (1995-2011). The lesions were analyzed according to their location and the patient's age and gender. The findings were compared with other published studies on reactive lesions. Results A total of 260 reactive lesion biopsies were accessed. focal fibrous hyperplasia (FFH) was the most common (38.5%), followed by pyogenic granuloma (PG) (34.6%), peripheral ossifying fibroma (POF) (17.7%) and peripheral giant cell granuloma (PGCG) (9.2%). The mean age of the patients was 33 years, with a range varying from 9 to 80 years. The LRHL occurred more commonly in females except focal fibrous hyperplasia, which showed male predilection. PG and POF were more common in the maxilla and FFH as well as PGCG were more common in the mandible. Conclusion This study indicates some differences in age and gender distribution as well as in location between the different lesions. The results of this study differ from those of other studies and the data presented here can be used as a guide for further multicenter studies. How to cite this article Ramu S, Rodrigues C. Reactive Hyperplastic Lesions of the Gingiva: A Retrospective Study of 260 Cases. World J Dent 2012;3(2):126-130.

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