scholarly journals EVALUATION OF DEVELOPMENT AND GROWTH OF PERIPHERAL GIANT CELL GRANULOMA USING OSTEOCALCIN, CD68, CD34, AND KI-67 MARKERS

2017 ◽  
Vol 63 (4) ◽  
pp. 3287-3300
Author(s):  
Naglaa Kamal ◽  
Rania El Behairy
Keyword(s):  
Giant Cell ◽  
Giant Cell Granuloma ◽  
Ki 67 ◽  
Peripheral Giant Cell Granuloma

Peripheral giant cell granuloma: A case report and review

2017 ◽  
Vol 4 (1) ◽  
pp. 1-3
Author(s):  
Tejavathi Nagaraj ◽  
Lakshmi Balraj ◽  
Pooja Sinha ◽  
Sreelakshmi Narayanan
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma

scholarly journals Massive peripheral giant cell granuloma associated with pregnancy

2016 ◽  
Author(s):  
Vikas Jain
Keyword(s):  
Oral Cavity ◽  
Giant Cell ◽  
Ovarian Hormones ◽  
Contributory Factor ◽  
Hormonal Changes ◽  
Giant Cell Granuloma ◽  
Young Females ◽  
Peripheral Giant Cell Granuloma ◽  
Nodular Lesions

Peripheral giant cell granuloma (PGCG) is a relatively Common reactive exophytic lesion of the oral cavity. The influence of hormones has been suggested as contributory factor in PGCG development and predominance of these lesions in young females as well as some previously reported pregnancy related cases support this belief. It has been observed that majority of lesions present in the 4th decade of life, when hormonal changes are more pronounced. Cailluette and Mattar in their study found that peripheral giant cell granuloma are under the influence of the ovarian hormones. However Chambers and Spector suggested peripheral giant cell granuloma to be enhanced by pregnancy rather than being pregnancy dependent. The responsiveness of gingiva to these hormones along with the immunosuppressive actions of the hormones contributes to the growth of the lesion. Clinically, PGCGs may present as polypoid or nodular lesions, predominantly bluish red with a smooth shiny or mamillated surface.This poster will review the literature available on the association of Massive Peripheral Giant Cell Granuloma With Pregnancy with focus on possible causes of PGCG during pregnancy.

Giant Cell Granuloma of the Temporal Bone: A Case Report With Immunohistochemical, Enzyme Histochemical, and In Vitro Studies

2003 ◽  
Vol 127 (9) ◽  
pp. 1217-1220 ◽  
Author(s):  
Xue-Fei Tian ◽  
Tie-Jun Li ◽  
Shi-Feng Yu
Keyword(s):  
Giant Cell ◽  
Temporal Bone ◽  
Mononuclear Cells ◽  
Giant Cells ◽  
Tartrate Resistant Acid Phosphatase ◽  
Giant Cell Granuloma ◽  
Ki 67 ◽  
The Right ◽  
Histochemical Reactivity

Abstract A case of giant cell granuloma (GCG) that occurred in the right temporal bone is reported. The lesion showed histologic features identical to GCG. The multinuclear giant cells (MGCs) in the lesion showed strong reactivity with CD68, but patchy staining for myeloid/histiocyte antigen, α-1-antitrypsin, α-1-antichymotrypsine, and lysozyme. Activity of tartrate-resistant acid phosphatase was also consistently detected in the MGCs. Some of the mononuclear cells of the lesion exhibited similar immunocytochemical and histochemical reactivity as the MGCs. Ki-67 staining, however, was only detected in the mononuclear cells. The MGCs isolated from the lesion presented characteristic morphology of osteoclasts and possessed the ability to excavate bone in vitro. Thus, the MGCs in GCG appeared to express both macrophage- and osteoclast-associated phenotypes. The mononuclear cells were the major proliferative elements in the lesion and a subpopulation of these cells may represent precursors of the MGCs.

scholarly journals Management of recurrent peripheral giant cell granuloma -a case report

2016 ◽  
Vol 4 (2) ◽  
pp. 138
Author(s):  
Santha Kumari Prathypaty ◽  
Santhi Priya Potharaju ◽  
Ravi Kanth Chintala ◽  
Satheesh Kumar Guvvala ◽  
Jai Krishna Srikanth Kolliboyana
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Chronic Infection ◽  
Tooth Extraction ◽  
Benign Tumor ◽  
Surgical Excision ◽  
Giant Cell Granuloma ◽  
Complete Excision ◽  
Periodontal Membrane ◽  
Peripheral Giant Cell Granuloma

Peripheral giant cell granuloma (PGCG) which is also called as Giant cell Epulis is one of the most common reactive hyperplastic lesions of the oral cavity. There are various etiologies relating PGCG which include local irritation, trauma, tooth extraction, irregular restorations, plaque, calculus, chronic infection & impacted food. One important other etiology of this benign tumor is its origin from periosteum or periodontal membrane. Excision of the lesion completely along with extraction of involved tooth is the option of treatment to prevent recurrence of the lesion in some cases. This case report describes the recurrence of the Peripheral giant cell granuloma even after complete excision in 3 months.Management of recurrent Peripheral giant cell granuloma by surgical excision of the lesion was carried out along with extraction of the associated tooth and curettage of the bone walls. Profuse bleeding after tooth extraction was managed by gel-spun. Periodic recalls doesn’t show any recurrence until one month.

scholarly journals Coexistence of hyperparathyroidism and peripheral giant cell granuloma of the jaw: A rare case report

2020 ◽  
Vol 9 (6) ◽  
pp. 3142 ◽  
Author(s):  
Naina Pattnaik ◽  
JagadishP Rajguru ◽  
SamarjeetJ Pattanaik ◽  
Debajyoti Bardhan ◽  
Bikash Nayak ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Rare Case ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma ◽  
Rare Case Report

scholarly journals Reactive Hyperplastic Lesions of the Gingiva: A Retrospective Study of 260 Cases

2012 ◽  
Vol 3 (2) ◽  
pp. 126-130 ◽  
Author(s):  
Sangeetha Ramu ◽  
Charlotte Rodrigues
Keyword(s):  
Retrospective Study ◽  
Giant Cell ◽  
Pyogenic Granuloma ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Multicenter Studies ◽  
Age And Gender ◽  
Peripheral Giant Cell Granuloma ◽  
The Mean ◽  
And Gender

ABSTRACT Objectives The purpose of the study was to analyze the frequency and distribution of gingival lesions in MR Ambedkar Dental College, Bengaluru. Materials and methods The material included the biopsies of all localized reactive hyperplastic lesions (LRHL) of the gingiva stored in the department's database (1995-2011). The lesions were analyzed according to their location and the patient's age and gender. The findings were compared with other published studies on reactive lesions. Results A total of 260 reactive lesion biopsies were accessed. focal fibrous hyperplasia (FFH) was the most common (38.5%), followed by pyogenic granuloma (PG) (34.6%), peripheral ossifying fibroma (POF) (17.7%) and peripheral giant cell granuloma (PGCG) (9.2%). The mean age of the patients was 33 years, with a range varying from 9 to 80 years. The LRHL occurred more commonly in females except focal fibrous hyperplasia, which showed male predilection. PG and POF were more common in the maxilla and FFH as well as PGCG were more common in the mandible. Conclusion This study indicates some differences in age and gender distribution as well as in location between the different lesions. The results of this study differ from those of other studies and the data presented here can be used as a guide for further multicenter studies. How to cite this article Ramu S, Rodrigues C. Reactive Hyperplastic Lesions of the Gingiva: A Retrospective Study of 260 Cases. World J Dent 2012;3(2):126-130.

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