scholarly journals Renal angiomyolipoma in pregnancy: surgical management with fetal preservation - Approach in a developing setting

2016 ◽  
Vol 6 (4) ◽  
Author(s):  
Fred O. Ugwumba ◽  
Emeka F. Nnakenyi ◽  
Okechukwu C. Okafor ◽  
Augustine C. Onuh ◽  
Paschalina C. Ezechukwu ◽  
...  
Keyword(s):  
Renal Function ◽  
Surgical Management ◽  
Management Strategy ◽  
Fetal Loss ◽  
Severe Bleeding ◽  
Renal Angiomyolipoma ◽  
Retroperitoneal Hemorrhage ◽  
Unique Challenge ◽  
Renal Tumours ◽  
In Pregnancy

Renal angiomyolipomas (RAML) are uncommon benign renal tumours that are associated with a tendency to rupture resulting in sometimes- torrential retroperitoneal hemorrhage as the Wunderlich syndrome or as severe potentially exsanguinating hematuria. When hemorrhage from RAML occurs in pregnancy it presents a unique challenge requiring timely and appropriately adapted intervention with the goal of preventing fatality, preserving renal function as well as preventing fetal loss if possible. We report the management of severe bleeding from RAML in pregnancy and highlight the need to adopt a management strategy that suits the practice environment and offers the patient standard and enduring care.

scholarly journals Surgical management of haemorrhaging renal angiomyolipoma in pregnancy

2015 ◽  
Vol 7 ◽  
pp. 89-92 ◽  
Author(s):  
P. Preece ◽  
B. Mees ◽  
B. Norris ◽  
M. Christie ◽  
T. Wagner ◽  
...  
Keyword(s):  
Surgical Management ◽  
Renal Angiomyolipoma ◽  
In Pregnancy

scholarly journals Massive haemorrhage due to spontaneous rupture of a giant renal angiomyolipoma – report of a rare case and review of the literature

2019 ◽  
Vol 17 (3) ◽  
pp. 264-268
Author(s):  
Iv. Novakov
Keyword(s):  
Spontaneous Rupture ◽  
Rare Case ◽  
Sudden Onset ◽  
Massive Hemorrhage ◽  
Retroperitoneal Tumor ◽  
Severe Complication ◽  
Severe Bleeding ◽  
Renal Angiomyolipoma ◽  
Retroperitoneal Hemorrhage ◽  
Life Threatening

Massive hemorrhage due to spontaneous rupture of a renal angiomyolipoma is a rare, but the most severe complication of this unusual tumor. The aim of this publication is to present a rare case of massive retroperitoneal hemorrhage and hemoperitoneum due to spontaneous rupture of giant renal angiomyolipoma. Case presentation: A 20-year-old woman, with a previous diagnosis of tuberous sclerosis and sudden onset of severe abdominal pain is presented. Median laparotomy on emergency was performed, with operative finding of hemoperitoneum and a giant ruptured retroperitoneal tumor with retroperitoneal hematoma. Gross pathology and histological examination determined the origin of the retroperitoneal tumor mass – angiomyolipoma, complicated with rupture and severe bleeding. In conclusion, this case presents rare, but the most severe complication of renal angiomyolipomas – spontaneous rupture of the tumor with life-threatening retroperitoneal bleeding.

Comparison of pregnancy outcomes after second trimester amniocentesis between procedures performed by experts and non-experts

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Tanapak Wisetmongkolchai ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
Suchaya Luewan ◽  
Kuntharee Traisrisilp ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Loss Rate ◽  
Fetal Loss ◽  
Adverse Pregnancy Outcomes ◽  
Expert Group ◽  
Second Trimester ◽  
Single Institution ◽  
Adverse Pregnancy ◽  
In Pregnancy ◽  
Singleton Pregnancies

AbstractObjectivesTo compare the rate of fetal loss in pregnancy after second trimester amniocentesis between procedures performed by experts and non-experts and to assess other pregnancy complications as secondary outcomes.MethodsA retrospective cohort study was performed on singleton pregnancies that underwent mid-trimester amniocenteses in a single institution. The fetal loss rates of procedures performed by experts and non-experts were collected and analyzed. Other adverse pregnancy outcomes were also examined.ResultsIn total, 14,450 amniocenteses were performed during the study period. These included 11,357 (78.6%) procedures in the group expert operators and 3,093 (21.4%) procedures in the group non-expert operators. In the non-expert group, the fetal loss rate was slightly increased but not significantly (p=0.24).In addition, the higher number of spontaneous abortions was associated with blood-stained amniotic fluid sample (p<0.001; RR=9.28). Multiple needle insertions also increased in the non-expert group significantly. However, no difference in pregnancy outcomes was found between in single and multiple needle insertions.ConclusionsThe amniocentesis procedures performed by the non-experts was not increase the fetal loss rate. However, the other adverse pregnancy outcomes, including preterm birth, low birth weight and fetal growth restriction were significantly increased in the non-expert group.

Metformin Combined LMWH Intervention in 25 Pregnant Women with History of Hyperlipidemia Pancreatitis in Pregnancy

2021 ◽  
Author(s):  
Mei Peng ◽  
Ya-Li Deng ◽  
Ling Yu ◽  
Yan-Ting Nie ◽  
Ting Luo ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Pregnancy Outcomes ◽  
Cohort Analysis ◽  
Intervention Group ◽  
Fetal Loss ◽  
Preventive Treatment ◽  
Full Term ◽  
Lipid Lowering ◽  
Neonatal Asphyxia ◽  
In Pregnancy

Objective: To explore the early preventive treatment of hypertriglyceridemia-induced acute pancreatitis (HTGP) in pregnancy. Methods: A retrospective cohort analysis was performed to examine the drug intervention on recurrent HTGP and related pregnancy outcomes among women who had HTGP in their past pregnancy and developed hyperlipidemia during the second pregnancy. Participants were identified through inpatient case records under a single physician at the clinic and divided into two groups. The intervention group was given metformin lipid-lowering combined with low-molecular-weight heparin to prevent thrombosis when hypertriglyceridemia was developed during the pregnancy. In contrast, the non-intervention group includes those who did not receive active drug treatment until they developed recurrent HTGP. Metabolic markers were also examined by comparing them with their respective past pregnancies. Results: All participants experienced elevated triglycerides during their two consecutive pregnancies. No pregnant women developed HTGP in the intervention group (n=12), while 10 of 13 (76.9%) women developed HTGP in the non-intervention group. Thus, the outcome seemed to be markedly different. In the intervention group, 11 women were gestated to term, and one was premature; one of 12 (8.3%) births was neonatal asphyxia; there was no low-weight birth, and the prognosis of mother and baby was favorable. Of 10 women who developed recurrent HTGP in the non-intervention group, four suffered from fetal loss, four had premature, and two had full-term delivery; among the three pregnant women without HTGP, one had a premature and two had full-term births; five of thirteen (38.5%) births were neonatal asphyxia. Conclusion: Pregnant women with HTGP history, if not treated, are likely to develop the condition recurrently during pregnancy, but timely intervention on hypertriglyceridemia with lipid-lowering and thrombosis-preventing seemed complete to reduce the recurrent HTGP and improve the pregnancy outcomes.

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