scholarly journals Massive haemorrhage due to spontaneous rupture of a giant renal angiomyolipoma – report of a rare case and review of the literature

2019 ◽  
Vol 17 (3) ◽  
pp. 264-268
Author(s):  
Iv. Novakov

Massive hemorrhage due to spontaneous rupture of a renal angiomyolipoma is a rare, but the most severe complication of this unusual tumor. The aim of this publication is to present a rare case of massive retroperitoneal hemorrhage and hemoperitoneum due to spontaneous rupture of giant renal angiomyolipoma. Case presentation: A 20-year-old woman, with a previous diagnosis of tuberous sclerosis and sudden onset of severe abdominal pain is presented. Median laparotomy on emergency was performed, with operative finding of hemoperitoneum and a giant ruptured retroperitoneal tumor with retroperitoneal hematoma. Gross pathology and histological examination determined the origin of the retroperitoneal tumor mass – angiomyolipoma, complicated with rupture and severe bleeding. In conclusion, this case presents rare, but the most severe complication of renal angiomyolipomas – spontaneous rupture of the tumor with life-threatening retroperitoneal bleeding.

Open Medicine ◽  
2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Selim Kervancioglu ◽  
Feyza Yilmaz

AbstractThe most undesired complication of renal angi- omyolipoma (AML) is bleeding. Because of tumor rupture, the bleeding can spread to the retroperitoneal field and can be severe enough to be life threatening. We report a case of retroperitoneal hemorrhage caused by a ruptured AML that was successfully treated with transarterial embolization with N-butyl cyanoacrylate.


2016 ◽  
Vol 6 (4) ◽  
Author(s):  
Fred O. Ugwumba ◽  
Emeka F. Nnakenyi ◽  
Okechukwu C. Okafor ◽  
Augustine C. Onuh ◽  
Paschalina C. Ezechukwu ◽  
...  

Renal angiomyolipomas (RAML) are uncommon benign renal tumours that are associated with a tendency to rupture resulting in sometimes- torrential retroperitoneal hemorrhage as the Wunderlich syndrome or as severe potentially exsanguinating hematuria. When hemorrhage from RAML occurs in pregnancy it presents a unique challenge requiring timely and appropriately adapted intervention with the goal of preventing fatality, preserving renal function as well as preventing fetal loss if possible. We report the management of severe bleeding from RAML in pregnancy and highlight the need to adopt a management strategy that suits the practice environment and offers the patient standard and enduring care.


2021 ◽  
Vol 4 (1) ◽  
pp. 76
Author(s):  
Rahadianto Tjandra ◽  
Maimun Z. Arthamin

<p>Hydatid Mole, also often called grape pregnancy, is a pregnancy characterized by abnormal trophoblast development. The incidence of hydatidiform mole per 1,000 pregnancies occurs in Asia. In Indonesia, in 2002 cases of hydatidiform mole were found 1: 123 pregnancy, and in 2003 found cases of hydatidiform mole 1: 245 pregnancy. While the results of research conducted in the same place in 2012-2013 obtained 39 cases of hydatidiform mole that were distributed based on age groups, parity, education, and hemoglobin levels of patients. Trophoblastic hyperthyroidism is a rare case but can be life threatening. Alpha subunit-human chorionic gonadotropin (HCG) is similar to alpha sub-unit-thyroid stimulating hormone (TSH). If HCG concentrations increase over a long period of time, it can increase free T4 and free T3 levels. In this patient there was also a sudden onset of hypertension, proteinuria 3+, ketonuria 3+, hematuria 3+, leukosituria 1+, bacteriuria which could possibly be caused by the occurrence of a pre-eclampsia or UTI in this patient. The cause of pre-eclampsia in molar pregnancy is thought to be due to excessive levels of soluble fms-like tyrosine kinase 1 (sFlt1) in the circulation, an endogenous anti-angiogenic protein that enters the maternal circulation after overproduction in the placenta.</p><p><strong>Keywords: Mola hydatidosa, HCG, TSH, sFlt1</strong></p>


2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Catarina Marçal da Silva ◽  
Rita Luz ◽  
Manuela Almeida ◽  
Daniel Pedro ◽  
Bárbara Paredes ◽  
...  

Spontaneous rupture of the uterine artery is a rare cause of hemoperitoneum during pregnancy. This is a life-threatening condition associated with maternal and fetal mortality. We describe a case of spontaneous rupture of the left uterine artery in a 32-year-old healthy pregnant woman with an uneventful pregnancy.


2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Stanislav Sotošek ◽  
Dean Markić ◽  
Josip Španjol ◽  
Kristian Krpina ◽  
Siniša Knežević ◽  
...  

Wünderlich syndrome (WS) is a urological emergency characterized by retroperitoneal hemorrhage. In most cases, bleeding occurs from a renal angiomyolipoma (AML) and may be the first manifestation of the disease. We report a female patient with bilateral WS due to the metachronous rupture of renal AMLs. Because the patient was stable and the tumor was not malignant, treatment was conservative. Follow-up revealed the full recovery of kidney function and the resolution of the hematoma.


2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Christopher A. Enakpene ◽  
Toni Stern ◽  
Marco J. Barzallo Salazar ◽  
Pradip Mukherjee

Background. Spontaneous rupture of an ovarian artery aneurysm is a rare but usually life-threatening event. It is most often associated with pregnancy or fibroids. Our case followed a normal vaginal delivery and then a delayed presentation with features similar to other less life-threatening postpartum conditions. The diagnosis could have been missed but for the meticulous and timely interventions which avoided catastrophic outcome.Case. This is a case of a multiparous woman with rupture of a left ovarian artery aneurysm, causing massive retroperitoneal hemorrhage and hematoma that required a combination of arterial embolization, percutaneous CT scan guided drainage, and surgical evacuation of the hematoma.Conclusion. Spontaneous rupture of ovarian artery should be considered as one of the differential diagnoses in the immediate postpartum period especially when the clinical symptoms do not correlate with the amount of blood loss. A high index of suspicion, prompt diagnosis, intervention, and a multidisciplinary approach in the management were the elements of a successful outcome in this case.


2021 ◽  
Vol 2 (3) ◽  
pp. 27-30
Author(s):  
Anupam Bhambhani ◽  
Sahithi Sharma ◽  
Aditi Nadamani

We report here a rare case of dabigatran-related spontaneous cardiac tamponade, which appeared in absence of the known risk factors that predispose the patient to bleed related to anticoagulant drugs. A 65-year-old lady presented to the emergency room with sudden onset dyspnea which woke her up in the early morning hours. Four days earlier, she had been started on dabigatran therapy for DVT. On examination, she was in shock. Transthoracic echocardiography confirmed cardiac tamponade. Emergent pericardiocentesis was done, draining 480 ml of haemorrhagic fluid, which tested negative for microbes and malignant cells. The patient recovered rapidly and fluid did not re-accumulate after withdrawal of dabigatran therapy. Spontaneous cardiac tamponade is rare with the use of direct anticoagulants, especially dabigatran, in the absence of predisposing risk factors. This case study highlights the need for clinicians to be cognizant of this potentially life-threatening adverse drug reaction of dabigatran so that appropriate timely action can be taken toward diagnosis and management of this complication.


2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Katharina Maria Bretterbauer ◽  
Dean Markić ◽  
Daniela Colleselli ◽  
Stephan Hruby ◽  
Ahmed Magdy ◽  
...  

Spontaneous, nontraumatic retroperitoneal hemorrhage or Wunderlich syndrome (WS) is a rare but potential life-threatening condition. In most patients a bleeding renal neoplasm is the cause of the retroperitoneal hematoma. The management of this condition includes a conservative approach in the hemodynamically stable patients and active treatment in the unstable patients. Active treatment includes angioembolization or surgery. If angioembolization is not available open surgery is in most cases the preferred approach. We present a patient with a spontaneously ruptured kidney due to a central renal angiomyolipoma, which was treated by laparoscopic nephrectomy.


2021 ◽  
Vol 9 ◽  
pp. 2050313X2110377
Author(s):  
Yasuhito Nakamura ◽  
Kiyoshi Doi ◽  
Syojiro Yamaguchi ◽  
Etsuji Umeda ◽  
Osamu Sakai ◽  
...  

We reported a rare case of spontaneous frank rupture of a small (4 mm) penetrating aortic ulcer in the ascending aorta resulted in catastrophic bleeding. The ulcer only created a pinhole wound in the adventitia without saccular aneurysms, intramural hematomas, or aortic dissections. Notably, the wound could be directly closed because the aortic wall was intact only 5 mm away from the bleeding site. The postoperative course was uneventful, and the patient was discharged on the 11th postoperative day. After 8 months, follow-up computed tomography showed no abnormality of the aortic wall at the repair site.


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