scholarly journals Septic arthritis of the temporomandibular joint in an infant

2015 ◽  
Vol 5 (2) ◽  
Author(s):  
Raymond Chuk ◽  
John Arvier ◽  
Barbara Laing ◽  
David Coman
Keyword(s):  
Early Diagnosis ◽  
Septic Arthritis ◽  
Temporomandibular Joint ◽  
Clinical Features ◽  
Surgical Management ◽  
Relevant Literature ◽  
Clinical Suspicion ◽  
Morbidity And Mortality ◽  
Severe Morbidity ◽  
High Degree

Infantile temporomandibular joint septic arthritis is an uncommon paediatric infection, but one which carries the potential for severe morbidity and mortality. Early diagnosis and aggressive medical and possibly surgical management is indicated for the best outcomes. The presenting clinical features are non-specific in a neonate and an infant; as such a high degree of clinical suspicion is required. We present the case of an eleven-month-old boy who has made a full recovery from an acute temporomandibular joint septic arthritis and review the relevant literature.

scholarly journals Updates in Diagnosis and Treatment of Acromegaly

2018 ◽  
Vol 14 (2) ◽  
pp. 57 ◽  
Author(s):  
Roula Zahr ◽  
Maria Fleseriu
Keyword(s):  
Growth Hormone ◽  
Pituitary Adenoma ◽  
Early Diagnosis ◽  
Rare Disease ◽  
Diagnostic Criteria ◽  
Clinical Features ◽  
Morbidity And Mortality ◽  
Diagnosis And Treatment ◽  
Personalised Therapy ◽  
Gh Excess

Acromegaly is a rare disease, caused largely by a growth hormone (GH) pituitary adenoma. Incidence is higher than previously thought. Due to increased morbidity and mortality, if not appropriately treated, early diagnosis efforts are essential. Screening is recommended for all patients with clinical features of GH excess. There is increased knowledge that classical diagnostic criteria no longer apply to all, and some patients can have GH excess with normal GH response to glucose. Treatment is multifactorial and personalised therapy is advised.

Steroid-Induced Osteonecrosis in Dermatology

2015 ◽  
Vol 19 (4) ◽  
pp. 358-360 ◽  
Author(s):  
Dominik Alex Nowak ◽  
Jensen Yeung
Keyword(s):  
Relevant Literature ◽  
Clinical Suspicion ◽  
Oral Steroid ◽  
Pubmed Search ◽  
High Degree

Background: Steroid-induced osteonecrosis is unpredictable and highly morbid. Methods: MEDLINE (Ovid) and PubMed search for relevant literature. Results: Oral steroid doses typically considered to be associated with the condition are >20 mg of prednisone (or equivalent) per day or >2 g within a period of 2 to 3 months. Symptoms may be vague. Conclusions: Dermatologists must exercise a high degree of clinical suspicion and warn patients about steroid-related risks and conditions for follow-up.

scholarly journals Neonatal Osteomyelitis and Septic Arthritis

2021 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Early Diagnosis ◽  
Antibiotic Therapy ◽  
Septic Arthritis ◽  
Preterm Infant ◽  
Clinical Suspicion ◽  
Diagnosis And Treatment ◽  
Empiric Antibiotic Therapy ◽  
International Literature ◽  
Extensive Review ◽  
Empiric Antibiotic

The purpose of this editorial is to perform an extensive review of the relevant international literature about neonatal osteomyelitis and septic arthritis, to indicate the value of clinical suspicion and of regular osteoarticular examination for the early diagnosis and treatment of the disease in the septicemic neonate or in the preterm infant, even when initial empiric antibiotic therapy is used, and to present illustrative cases.

Dengue fever in infants: report of three cases

2016 ◽  
Vol 47 (2) ◽  
pp. 173-176
Author(s):  
Sumit Mehndiratta ◽  
Ritika Singhal ◽  
Krishnan Rajeshwari ◽  
Anand P Dubey
Keyword(s):  
Young Adults ◽  
Dengue Fever ◽  
Clinical Features ◽  
Wide Spectrum ◽  
Clinical Manifestations ◽  
Clinical Suspicion ◽  
Diagnostic Methods ◽  
Children And Young Adults ◽  
High Degree

Dengue fever has classically been described as a disease of children and young adults. Infants are naturally protected by virtue of maternally derived immunoglobulins, especially in endemic countries. The resurgence of dengue, coupled with the availability of early and sensitive diagnostic methods and a high degree of clinical suspicion, has led to an increasing number of infants being diagnosed. There is a wide spectrum of clinical manifestations, particularly in infancy. Here we describe three cases presenting with diverse clinical features, their subsequent management and outcome.

scholarly journals Gastric Necrosis due to Acute Massive Gastric Dilatation

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Ibrahim Aydin ◽  
Ahmet Pergel ◽  
Ahmet Fikret Yucel ◽  
Dursun Ali Sahin ◽  
Ender Ozer
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Bulimia Nervosa ◽  
Relevant Literature ◽  
Mortality Rates ◽  
Morbidity And Mortality ◽  
Diagnosis And Treatment ◽  
Gastric Dilatation ◽  
Gastric Necrosis ◽  
Acute Gastric Dilatation

Gastric necrosis due to acute massive gastric dilatation is relatively rare. Vascular reasons, herniation, volvulus, acute gastric dilatation, anorexia, and bulimia nervosa play a role in the etiology of the disease. Early diagnosis and treatment are highly important as the associated morbidity and mortality rates are high. In this case report, we present a case of gastric necrosis due to acute gastric dilatation accompanied with the relevant literature.

Triple A syndrome: a case report

2020 ◽  
pp. 004947552096194
Author(s):  
Piyush Manoria
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Autosomal Recessive ◽  
Autosomal Recessive Disorder ◽  
Morbidity And Mortality ◽  
Adrenal Failure ◽  
Triple A Syndrome ◽  
Rare Autosomal Recessive Disorder ◽  
High Degree

Triple A syndrome is a rare autosomal recessive disorder characterised by alacrimia, achalasia and adrenal failure. It was first reported by Allgrove in 1978 and 100 cases have been reported worldwide. This case report concerns a 24-year-old woman who was referred for evaluation of dysphagia and was finally diagnosed as such a case. A high degree of suspicion enables all the components of this syndrome to be searched for, as early diagnosis can reduce the morbidity and mortality.

scholarly journals Early Diagnosis and Surgical Management of Acoustic Neuroma: Is it Cost Effective?

1989 ◽  
Vol 82 (6) ◽  
pp. 329-332 ◽  
Author(s):  
D A Moffat ◽  
D G Hardy
Keyword(s):  
Early Diagnosis ◽  
Surgical Management ◽  
Acoustic Neuroma ◽  
Surgical Intervention ◽  
Cost Effective ◽  
Morbidity And Mortality ◽  
Diagnosis And Treatment ◽  
Acoustic Neuromas ◽  
Acoustic Nerve ◽  
Microsurgical Techniques

Audiological and radiological advances and refinement of microsurgical techniques have facilitated the diagnosis and excision of very small acoustic nerve tumours with a low morbidity and mortality. Is this cost effective? In an attempt to answer this question, an analysis of 66 cases of surgically treated acoustic neuromas is presented. This represents a part of a series of otoneurosurgical procedures carried out at Addenbrooke's Hospital over the last five years. By studying the relative morbidity of early and late surgical intervention in these cases, and by costing the exercise, the justification for early diagnosis and treatment is presented both in financial and human terms.

scholarly journals Group A Streptococcus necrotising myositis of the limbs secondary to cavitating pneumonia

2021 ◽  
Vol 14 (4) ◽  
pp. e239929
Author(s):  
Manveer Rahi ◽  
Malcolm Will
Keyword(s):  
Early Diagnosis ◽  
Clinical Diagnosis ◽  
Surgical Management ◽  
Group A Streptococcus ◽  
Rare Complication ◽  
Clinical Suspicion ◽  
Diagnostic Tools ◽  
Confounding Factors ◽  
Limb Pain ◽  
Group A

Necrotising myositis is a rare complication of Group A Streptococcus infection requiring early and aggressive surgical management to prevent mortality. However, early diagnosis is difficult due to non-specific initial presentation and a low index of clinical suspicion given the paucity of cases. We highlight these challenges and present a case of a 22-year-old woman presenting with cough, fever and severe limb pain refractory to analgesia during the COVID-19 pandemic. We outline potential confounding factors that can delay intervention and offer diagnostic tools that can aid clinical diagnosis of necrotising myositis. In reporting this case, we hope to raise awareness among clinicians to avoid these pitfalls.

Reconsidering NMIHBA Core Features: Macrocephaly Is Not a So Unusual Sign in PRUNE1-Related Encephalopathy

2020 ◽  
Author(s):  
Roberta Battini ◽  
Enrico Bertini ◽  
Roberta Milone ◽  
Chiara Aiello ◽  
Rosa Pasquariello ◽  
...  
Keyword(s):  
Nervous System ◽  
Differential Diagnosis ◽  
Clinical Features ◽  
Neurodevelopmental Disorder ◽  
Recurrent Mutation ◽  
Clinical Suspicion ◽  
Alexander Disease ◽  
Brain Anomalies ◽  
Progressive Encephalopathy ◽  
Core Features

Abstract PRUNE1-related disorders manifest as severe neurodevelopmental conditions associated with neurodegeneration, implying a differential diagnosis at birth with static encephalopathies, and later with those manifesting progressive brain damage with the involvement of both the central and the peripheral nervous system.Here we report on another patient with PRUNE1 (p.Asp106Asn) recurrent mutation, whose leukodystrophy, inferior olives hyperintensity, and macrocephaly led to the misleading clinical suspicion of Alexander disease. Clinical features, together with other recent descriptions, suggest avoiding the term “microcephaly” in defining this disorder that could be renamed “neurodevelopmental disorder with progressive encephalopathy, hypotonia, and variable brain anomalies” (NPEHBA).

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