scholarly journals Abnormal Cardiac Structure and Function in the Metabolic Syndrome: A Population-Based Study

2008 ◽  
Vol 83 (12) ◽  
pp. 1350-1357 ◽  
Author(s):  
Bilal Aijaz ◽  
Khawaja A. Ammar ◽  
Francisco Lopez-Jimenez ◽  
Margaret M. Redfield ◽  
Steven J. Jacobsen ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Population Based ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Population Based Study ◽  
The Metabolic Syndrome ◽  
Cardiac Structure And Function ◽  
And Function

Influence of metabolic syndrome on cardiac structure and function and arterial stiffness in healthy children

2009 ◽  
Vol 18 ◽  
pp. S254-S255
Author(s):  
Walter P. Abhayaratna ◽  
Satoru Sakuragi ◽  
Katrina Hayes ◽  
Christine Brown ◽  
Richard D. Telford
Keyword(s):  
Metabolic Syndrome ◽  
Arterial Stiffness ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Healthy Children ◽  
Cardiac Structure And Function ◽  
And Function

scholarly journals Association of Exercise Capacity, Cardiac Function, and Coronary Artery Calcification with Components for Metabolic Syndrome

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Hyun Jun Kim ◽  
Ji Hee Kim ◽  
Min Cheol Joo
Keyword(s):  
Metabolic Syndrome ◽  
Coronary Artery ◽  
Exercise Capacity ◽  
Structure And Function ◽  
The Other ◽  
Cardiac Structure ◽  
Group 3 ◽  
Cardiac Structure And Function ◽  
And Function ◽  
Group 1

Purpose. The purpose of this study was to investigate the association of exercise capacity, cardiac function, and coronary artery calcification (CAC) with components of metabolic syndrome in Korean adults. Method. Medical records of healthy adults who underwent exercise tolerance test (ETT), coronary CT angiography (CTA), and echocardiography of the heart for cardiac health check-up were retrospectively reviewed. Patients who had a history of severe cardiovascular disease or could not perform ETT due to other musculoskeletal problems were excluded. Subjects were classified into groups based on the number of components for metabolic syndrome: no component (Group 1, n=90), 1, 2 components (Group 2, n=321), and 3 or more components (Group 3, n=154). Exercise capacity was assessed using the symptom-limited ETT, and CAC score was obtained using the coronary CTA and Agatston score. Cardiac structure and function were assessed using echocardiography. Results. A total of 565 patients (mean (SD) age 59.5 (9.1), 340 men, 225 women) were selected. Exercise capacity was significantly lower in Group 3 than in the other groups (p<0.05). The CAC score was significantly higher in Group 3 than in the other groups (p<0.05). Compared to the other groups, echocardiography findings in Group 3 showed a greater hypertrophy of the left ventricle and reduction in the diastolic function (p<0.05). Exercise capacity, CAC score, cardiac structure, and function were different between the 3 groups, where a tendency to worsen was observed from Group 1 to Group 3. Conclusion. Metabolic syndrome decreases exercise capacity of the patient and contributes to CAC, thereby increasing the risk for cardiovascular diseases and deterioration in cardiac structure and function. Therefore, early detection of metabolic syndrome and subsequently the prevention and management of heart disease are necessary.

scholarly journals Cardiac structure and function with and without metabolic syndrome: the Echocardiographic Study of Latinos (Echo-SOL)

2018 ◽  
Vol 6 (1) ◽  
pp. e000484 ◽  
Author(s):  
Melissa Burroughs Peña ◽  
Katrina Swett ◽  
Neil Schneiderman ◽  
Daniel M Spevack ◽  
Sonia G Ponce ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Longitudinal Strain ◽  
Left Ventricular ◽  
Normal Weight ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Echocardiographic Study ◽  
Confounding Variables ◽  
Cardiac Structure And Function ◽  
And Function

ObjectiveWe assessed the hypothesis that metabolic syndrome is associated with adverse changes in cardiac structure and function in participants of the Echocardiographic Study of Latinos (Echo-SOL).MethodsNon-diabetic Echo-SOL participants were included in this cross-sectional analysis. Metabolic syndrome was defined according to the American Heart Association/National Heart, Lung, and Blood Institute 2009 Joint Scientific Statement. Survey multivariable linear regression analyses using sampling weights were used adjusting for multiple potential confounding variables. Additional analysis was stratified according to the presence/absence of obesity (body mass index (BMI) ≥25 kg/m2) and the presence/absence of metabolic syndrome.ResultsWithin Echo-SOL, 1260 individuals met inclusion criteria (59% female; mean age 55.2 years). Compared with individuals without metabolic syndrome, those with metabolic syndrome had lower medial and lateral E′ velocities (−0.4 cm/s, (SE 0.1), p=0.0002; −0.5 cm/s (0.2), p=0.02, respectively), greater E/E′ (0.5(0.2), p=0.01) and worse two-chamber left ventricular longitudinal strain (0.9%(0.3), p=0.009), after adjusting for potential confounding variables. Increased left ventricular mass index (9.8 g/m2 (1.9), p<0.0001 and 7.5 g/m2 (1.7), p<0.0001), left ventricular end-diastolic volume (11.1 mL (3.0), p=0.0003 and 13.3 mL (2.7), p<0.0001), left ventricular end-systolic volume (5.0 mL (1.4), p=0.0004 and 5.7 mL (1.3) p<0.0001) and left ventricular stroke volume (10.2 mL (1.8), p<0.0001 and 13.0 mL (2.0), p<0.0001) were observed in obese individuals with and without metabolic syndrome compared with individuals with normal weight without metabolic syndrome. In sensitivity analyses, individuals with normal weight (BMI <25 kg/m2) and metabolic syndrome had worse left ventricular global longitudinal strain (2.1%(0.7), p=0.002) and reduced left ventricular ejection fraction (−3.5%(1.4), p=0.007) compared with normal-weight individuals without metabolic syndrome.ConclusionsIn a sample of US Hispanics/Latinos metabolic syndrome was associated with worse left ventricular systolic and diastolic function. Adverse changes in left ventricular size and function were observed in obese individuals with and without metabolic syndrome but decreased left ventricular function was also present in normal-weight individuals with metabolic syndrome.

scholarly journals Impact of the severity of end-stage liver disease in cardiac structure and function

2013 ◽  
Vol 12 (1) ◽  
pp. 85-91 ◽  
Author(s):  
Odilson Marcos Silvestre ◽  
Fernando Bacal ◽  
Danusa de Souza Ramos ◽  
Jose L. Andrade ◽  
Meive Furtado ◽  
...  
Keyword(s):  
Liver Disease ◽  
Structure And Function ◽  
Cardiac Structure ◽  
End Stage Liver Disease ◽  
Cardiac Structure And Function ◽  
End Stage ◽  
And Function

scholarly journals Development of a semi-automated segmentation tool for high frequency ultrasound image analysis of mouse echocardiograms

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kristi Powers ◽  
Raymond Chang ◽  
Justin Torello ◽  
Rhonda Silva ◽  
Yannick Cadoret ◽  
...  
Keyword(s):  
Image Analysis ◽  
Automated Analysis ◽  
Structure And Function ◽  
Ultrasound Images ◽  
Cardiac Structure ◽  
Short Axis ◽  
Pixel Intensity ◽  
Cardiac Structure And Function ◽  
And Function

AbstractEchocardiography is a widely used and clinically translatable imaging modality for the evaluation of cardiac structure and function in preclinical drug discovery and development. Echocardiograms are among the first in vivo diagnostic tools utilized to evaluate the heart due to its relatively low cost, high throughput acquisition, and non-invasive nature; however lengthy manual image analysis, intra- and inter-operator variability, and subjective image analysis presents a challenge for reproducible data generation in preclinical research. To combat the image-processing bottleneck and address both variability and reproducibly challenges, we developed a semi-automated analysis algorithm workflow to analyze long- and short-axis murine left ventricle (LV) ultrasound images. The long-axis B-mode algorithm executes a script protocol that is trained using a reference library of 322 manually segmented LV ultrasound images. The short-axis script was engineered to analyze M-mode ultrasound images in a semi-automated fashion using a pixel intensity evaluation approach, allowing analysts to place two seed-points to triangulate the local maxima of LV wall boundary annotations. Blinded operator evaluation of the semi-automated analysis tool was performed and compared to the current manual segmentation methodology for testing inter- and intra-operator reproducibility at baseline and after a pharmacologic challenge. Comparisons between manual and semi-automatic derivation of LV ejection fraction resulted in a relative difference of 1% for long-axis (B-mode) images and 2.7% for short-axis (M-mode) images. Our semi-automatic workflow approach reduces image analysis time and subjective bias, as well as decreases inter- and intra-operator variability, thereby enhancing throughput and improving data quality for pre-clinical in vivo studies that incorporate cardiac structure and function endpoints.

scholarly journals The mitral regurgitation effects of cardiac structure and function in left ventricular noncompaction

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Qing Zou ◽  
Rong Xu ◽  
Xiao Li ◽  
Hua-yan Xu ◽  
Zhi-gang Yang ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Nyha Class ◽  
Left Ventricular ◽  
Structure And Function ◽  
Left Ventricular Geometry ◽  
Cardiac Structure ◽  
Left Ventricular Noncompaction ◽  
Ventricular Noncompaction ◽  
Cardiac Structure And Function ◽  
And Function

AbstractThis study evaluated the effects of mitral regurgitation (MR) on cardiac structure and function in left ventricular noncompaction (LVNC) patients. The clinical and cardiovascular magnetic resonance (CMR) data for 182 patients with noncompaction or hypertrabeculation from three institutes were retrospectively included. We analyzed the difference in left ventricular geometry, cardiac function between LVNC patients with and without MR. The results showed that patients with MR had a worse New York Heart Association (NYHA) class and a higher incidence of arrhythmia (P < 0.05). MR occurred in 48.2% of LVNC patients. Compared to LVNC patients without MR, the two-dimensional sphericity index, maximum/minimum end-diastolic ratio and longitudinal shortening in LVNC patients with MR were lower (P < 0.05), and the peak longitudinal strain (PLS) of the global and segmental myocardium were obviously reduced (P < 0.05). No significant difference was found in strain in LVNC patients with different degree of MR; end diastolic volume, end systolic volume, and global PLS were statistically associated with MR and NYHA class (P < 0.05), but the non-compacted to compacted myocardium ratio had no significant correlation with them. In conclusion, the presence of MR is common in LVNC patients. LVNC patients with MR feature more severe morphological and functional changes. Hypertrabeculation is not an important factor affecting structure and function at the heart failure stage.

Sign in / Sign up

Export Citation Format

Share Document