scholarly journals Association of Exercise Capacity, Cardiac Function, and Coronary Artery Calcification with Components for Metabolic Syndrome

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Hyun Jun Kim ◽  
Ji Hee Kim ◽  
Min Cheol Joo
Keyword(s):  
Metabolic Syndrome ◽  
Coronary Artery ◽  
Exercise Capacity ◽  
Structure And Function ◽  
The Other ◽  
Cardiac Structure ◽  
Group 3 ◽  
Cardiac Structure And Function ◽  
And Function ◽  
Group 1

Purpose. The purpose of this study was to investigate the association of exercise capacity, cardiac function, and coronary artery calcification (CAC) with components of metabolic syndrome in Korean adults. Method. Medical records of healthy adults who underwent exercise tolerance test (ETT), coronary CT angiography (CTA), and echocardiography of the heart for cardiac health check-up were retrospectively reviewed. Patients who had a history of severe cardiovascular disease or could not perform ETT due to other musculoskeletal problems were excluded. Subjects were classified into groups based on the number of components for metabolic syndrome: no component (Group 1, n=90), 1, 2 components (Group 2, n=321), and 3 or more components (Group 3, n=154). Exercise capacity was assessed using the symptom-limited ETT, and CAC score was obtained using the coronary CTA and Agatston score. Cardiac structure and function were assessed using echocardiography. Results. A total of 565 patients (mean (SD) age 59.5 (9.1), 340 men, 225 women) were selected. Exercise capacity was significantly lower in Group 3 than in the other groups (p<0.05). The CAC score was significantly higher in Group 3 than in the other groups (p<0.05). Compared to the other groups, echocardiography findings in Group 3 showed a greater hypertrophy of the left ventricle and reduction in the diastolic function (p<0.05). Exercise capacity, CAC score, cardiac structure, and function were different between the 3 groups, where a tendency to worsen was observed from Group 1 to Group 3. Conclusion. Metabolic syndrome decreases exercise capacity of the patient and contributes to CAC, thereby increasing the risk for cardiovascular diseases and deterioration in cardiac structure and function. Therefore, early detection of metabolic syndrome and subsequently the prevention and management of heart disease are necessary.

scholarly journals Postnatal undernutrition alters adult female mouse cardiac structure and function leading to limited exercise capacity

2019 ◽  
Vol 597 (7) ◽  
pp. 1855-1872 ◽  
Author(s):  
David P. Ferguson ◽  
Tanner O. Monroe ◽  
Celia Pena Heredia ◽  
Ryan Fleischmann ◽  
George G. Rodney ◽  
...  
Keyword(s):  
Exercise Capacity ◽  
Adult Female ◽  
Female Mouse ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Cardiac Structure And Function ◽  
And Function

Influence of metabolic syndrome on cardiac structure and function and arterial stiffness in healthy children

2009 ◽  
Vol 18 ◽  
pp. S254-S255
Author(s):  
Walter P. Abhayaratna ◽  
Satoru Sakuragi ◽  
Katrina Hayes ◽  
Christine Brown ◽  
Richard D. Telford
Keyword(s):  
Metabolic Syndrome ◽  
Arterial Stiffness ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Healthy Children ◽  
Cardiac Structure And Function ◽  
And Function

scholarly journals Abnormal Cardiac Structure and Function in the Metabolic Syndrome: A Population-Based Study

2008 ◽  
Vol 83 (12) ◽  
pp. 1350-1357 ◽  
Author(s):  
Bilal Aijaz ◽  
Khawaja A. Ammar ◽  
Francisco Lopez-Jimenez ◽  
Margaret M. Redfield ◽  
Steven J. Jacobsen ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Population Based ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Population Based Study ◽  
The Metabolic Syndrome ◽  
Cardiac Structure And Function ◽  
And Function

scholarly journals Cardiac structure and function with and without metabolic syndrome: the Echocardiographic Study of Latinos (Echo-SOL)

2018 ◽  
Vol 6 (1) ◽  
pp. e000484 ◽  
Author(s):  
Melissa Burroughs Peña ◽  
Katrina Swett ◽  
Neil Schneiderman ◽  
Daniel M Spevack ◽  
Sonia G Ponce ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Longitudinal Strain ◽  
Left Ventricular ◽  
Normal Weight ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Echocardiographic Study ◽  
Confounding Variables ◽  
Cardiac Structure And Function ◽  
And Function

ObjectiveWe assessed the hypothesis that metabolic syndrome is associated with adverse changes in cardiac structure and function in participants of the Echocardiographic Study of Latinos (Echo-SOL).MethodsNon-diabetic Echo-SOL participants were included in this cross-sectional analysis. Metabolic syndrome was defined according to the American Heart Association/National Heart, Lung, and Blood Institute 2009 Joint Scientific Statement. Survey multivariable linear regression analyses using sampling weights were used adjusting for multiple potential confounding variables. Additional analysis was stratified according to the presence/absence of obesity (body mass index (BMI) ≥25 kg/m2) and the presence/absence of metabolic syndrome.ResultsWithin Echo-SOL, 1260 individuals met inclusion criteria (59% female; mean age 55.2 years). Compared with individuals without metabolic syndrome, those with metabolic syndrome had lower medial and lateral E′ velocities (−0.4 cm/s, (SE 0.1), p=0.0002; −0.5 cm/s (0.2), p=0.02, respectively), greater E/E′ (0.5(0.2), p=0.01) and worse two-chamber left ventricular longitudinal strain (0.9%(0.3), p=0.009), after adjusting for potential confounding variables. Increased left ventricular mass index (9.8 g/m2 (1.9), p<0.0001 and 7.5 g/m2 (1.7), p<0.0001), left ventricular end-diastolic volume (11.1 mL (3.0), p=0.0003 and 13.3 mL (2.7), p<0.0001), left ventricular end-systolic volume (5.0 mL (1.4), p=0.0004 and 5.7 mL (1.3) p<0.0001) and left ventricular stroke volume (10.2 mL (1.8), p<0.0001 and 13.0 mL (2.0), p<0.0001) were observed in obese individuals with and without metabolic syndrome compared with individuals with normal weight without metabolic syndrome. In sensitivity analyses, individuals with normal weight (BMI <25 kg/m2) and metabolic syndrome had worse left ventricular global longitudinal strain (2.1%(0.7), p=0.002) and reduced left ventricular ejection fraction (−3.5%(1.4), p=0.007) compared with normal-weight individuals without metabolic syndrome.ConclusionsIn a sample of US Hispanics/Latinos metabolic syndrome was associated with worse left ventricular systolic and diastolic function. Adverse changes in left ventricular size and function were observed in obese individuals with and without metabolic syndrome but decreased left ventricular function was also present in normal-weight individuals with metabolic syndrome.

Sign in / Sign up

Export Citation Format

Share Document