scholarly journals Assessment of Health-Related Quality of Life: The Cinderella of Peritoneal Dialysis?

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Mercedes Moreiras-Plaza ◽  
Raquel Blanco-García ◽  
Cinthya Raquel Cossio-Aranibar ◽  
Gloria Rodriguez-Goyanes

The studies of quality of life (QoL) are becoming increasingly interesting in clinical setting because their findings have implications for making decisions on resource allocation and health policies. The assessment of health-related QoL is especially directed to patients with chronic illnesses that cause progressive deterioration and limitations, and consume the bulk of financial resources for health. Among these chronic kidney disease and, more specifically the renal replacement therapy, is an important condition. Due to the diagnostic and therapeutic advances, we see a gradual increase both in the number of the dialysis population and its age, which leads to a growing interest in the study of these patients' QoL, as evidenced by more than one thousand articles published on this subject.

Author(s):  
Jeehee Pyo ◽  
Ji-Hyun Lee ◽  
Mina Lee ◽  
Minsu Ock

Abstract Background: Disease burden created by periodontal disease has been recognized as a global challenge. The burden of medical expenses is expected to increase continuously, parallel to the growth of the elderly population. Periodontal disease causes tooth loss if not treated early, and advanced periodontitis can cause a decline in chewing ability and word pronunciation as well as aesthetic function. These results diminish the health-related quality of life (QOL) for various populations, particularly the elderly, adults, pregnant women, and workers. Thus, not only is early detection and management of the disease necessary, but also a systematic strategy for the prevention of periodontal diseaseMethods: Adults 19 years of age or older diagnosed with chronic gingivitis (K05.1) or chronic periodontitis (K05.3) under the ICD-10 codes were selected to participate in the study. Among the patients visiting the dental outpatient department, the study participants were chosen for our sample. A total of 20 participants were informed of the purpose of the study and gave consent to participate in in-depth interviews.Results: The analysis results were summarized into the four upper categories of ‘Interfering Element for Dental Care,’ ‘Declined Quality of Life caused by Dental Disease,’ ‘Satisfaction Elements after Treatment of Dental Disease,’ ‘Improvements for Voluntary Dental Care.’ The treatment of periodontal disease has improved the health-related quality of life and enabled the participants to have positive health behaviors for dental care. Furthermore, they recognized the severity of periodontal disease and the importance of dental examinations. It enabled them to be aware of the need of societal effort for dental care awareness.Conclusions: This study was an in-depth examination of the health-related QOL of periodontal patients through qualitative research methodology. The experiences of periodontal disease identified by this study can not only help to assess the adequacy of the current dental health-related QOL assessment tools but also recognize unmet needs regarding periodontal disease and, ultimately, to raise the awareness of periodontal disease among the general public. Based on this research, we expect that research on health-related QOL on periodontal disease would expand and revitalize the dental health system and practices.


2020 ◽  
Vol 54 (3) ◽  
pp. 164-172
Author(s):  
Joel Faronbi ◽  
Aishat Ajadi ◽  
Robbert Gobbens

Background: The increase in life expectancy has brought about a higher prevalence of chronic illnesses among older people.Objectives: To identify common chronic illnesses among older adults, to examine the influence of such conditions on their Health-Related Quality of Life (HRQoL), and to determine factors predicting their HRQoL.Method: A population-based cross-sectional study was conducted involving 377 individuals aged 60 years and above who were selected using multi-stage sampling techniques in Olorunda Local Government, Osun State, Nigeria. Data were collected using an interviewer-administered questionnaire comprising socio-demographic characteristics, chronic illnesses, and the World Health Organization quality of life instrument (WHOQOL-BREF) containing physical health, psychological, social relationships, and environmental domains.Results: About half (51.5%) of the respondents reported at least one chronic illness which has lasted for 1–5 years (43.3%). The prevalence of hypertension was 36.1%, diabetes 13.9% and arthritis 13.4%. Respondents with chronic illness had significantly lower HRQoL overall and in the physical health, social relationships and the environmental domains (all p<0.05) compared to those without a chronic illness. Factors that predicted HRQoL include age, marital status, level of education, the presence of chronic illness and prognosis of the condition.Conclusion: This study concluded that chronic illness is prevalent in Nigerian older people and significantly influence their HRQoL. Age, marital status, and level of education were associated with HRQoL in this group.Keywords: Chronic illness, Health-Related Quality of Life, Older adults, Socio-demographic factorsFunding: Postdoctoral fellowship from Consortium for Advanced Research Training in Afric


Nutrients ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 1144 ◽  
Author(s):  
Ken-ichi Ishibashi ◽  
Machiko Nishioka ◽  
Nobuteru Onaka ◽  
Madoka Takahashi ◽  
Daisuke Yamanaka ◽  
...  

Euglena gracilis EOD-1, a microalgal strain known for high yields of the β-1, 3-glucan paramylon, is suggested to function as a dietary fiber and enhance immunity. Here, we aimed to investigate the effects of E. gracilis EOD-1 biomass (EOD1BM) ingestion on immunoglobulin A (IgA) antibody titers in saliva, its reactivity, and the health-related quality of life (QOL) in humans. Reacting human immunoglobulin preparations and saliva with paramylon granules revealed the presence of anti-paramylon antibodies in the blood and saliva. We conducted a placebo-controlled, double-blind, crossover study involving 13 healthy subjects who ingested the placebo or EOD1BM for 4 weeks. Saliva was collected from each subject before and after ingestion, and IgA titers and E. gracilis EOD-1 paramylon (EOD1PM) reactivity were compared. In the EOD1BM Ingestion group, the anti-EOD1PM IgA content and titer increased after EOD1BM ingestion. No such change was observed in the Placebo group. Furthermore, the health-related QOL, especially mental health, increased in the EOD1BM Ingestion group. Thus, EOD1BM ingestion led to the production of paramylon (PM)-specific IgA antibody and increased salivary IgA antibody titers. We demonstrate that EOD1BM ingestion enhanced the immunity in the mucosal surface, evoked an antigen-specific response, and increased the health-related QOL, thereby contributing to health improvement.


2014 ◽  
Vol 28 (2) ◽  
pp. 113-126 ◽  
Author(s):  
Sun Ju Chang ◽  
Eun-Ok Im

The purpose of the study was to develop a situation-specific theory for explaining health-related quality of life (QOL) among older South Korean adults with type 2 diabetes. To develop a situation-specific theory, three sources were considered: (a) the conceptual model of health promotion and QOL for people with chronic and disabling conditions (an existing theory related to the QOL in patients with chronic diseases); (b) a literature review using multiple databases including Cumulative Index for Nursing and Allied Health Literature (CINAHL), PubMed, PsycINFO, and two Korean databases; and (c) findings from our structural equation modeling study on health-related QOL in older South Korean adults with type 2 diabetes. The proposed situation-specific theory is constructed with six major concepts including barriers, resources, perceptual factors, psychosocial factors, health-promoting behaviors, and health-related QOL. The theory also provides the interrelationships among concepts. Health care providers and nurses could incorporate the proposed situation-specific theory into development of diabetes education programs for improving health-related QOL in older South Korean adults with type 2 diabetes.


2020 ◽  
pp. 073346482096651
Author(s):  
Hye-Min Park ◽  
Jinsei Jung ◽  
Jong-Koo Kim ◽  
Yong-Jae Lee

This study investigated the relationship of tinnitus with mental health and health-related quality of life (QoL) in older people. Data source included 5,129 community-dwelling men and women ≥60 years old from the Korean National Health and Nutrition Examination Survey. Tinnitus was categorized into three groups: normal, tolerable tinnitus, and annoying tinnitus. Mental health and health-related QoL were assessed according to three dimensions (depressive mood, psychological distress, and suicidal ideation) and five domains (impaired mobility, impaired self-care, impaired usual activities, pain/discomfort, and anxiety/depression). The odds ratios (ORs) and 95% confidence intervals (CIs) of mental health and health-related QoL were calculated using multiple logistic regression analyses. Annoying tinnitus was positively and independently associated with deteriorated mental health and health-related QoL, suggesting comprehensive care is needed in older people with annoying tinnitus.


SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A143-A144
Author(s):  
Kelly Showen ◽  
Kathleen O’Hora ◽  
Beatriz Hernandez ◽  
Laura Lazzeroni ◽  
Jamie Zeitzer ◽  
...  

Abstract Introduction Insomnia affects 30–48% of older adults and impairs health-related quality of life (HRQoL). Numerous studies report Cognitive Behavioral Therapy (CBT-I) as an effective non-pharmacological treatment for insomnia symptoms, with few examining the impact of CBT-I on mental and physical aspects of HRQoL. While limited research suggests that CBT-I leads to improvements in HRQoL, the impact of the cognitive versus behavioral components of CBT-I on HRQoL is unknown. Methods 128 older adults with insomnia (mean age=69, 66% female, 19% minority) were randomized to receive cognitive therapy (CT), behavior therapy (BT), or CBT-I. The Short Form (36) Health Survey (SF-36) was collected at baseline, post-treatment and six-month follow-up. Split-plot linear mixed models with age and sex as covariates to assess within and between subject changes were used to test intervention, time, and interaction effects on the mental health and physical well-being domains of HRQoL. Significance for all effects was defined as p &lt; 0.05. The effect size (d) was calculated by dividing the difference between means by the root-mean-squared error of the mixed effects model. Results The mental health-related QoL improved over time independent of treatment (Main effect of time: F(2, 202) = 6.51, p &lt; 0.002). The interaction failed to reach significance (Interaction: F(4, 202) = 1.19, p = .31). Simple effects revealed significant improvements among CBT-I participants at six months (p = .02, d = .53) and CT participants at post-treatment (p = .00, d = .79) and six months (p = .03, d = .66), but not among BT participants for either time point (p = .32, d = .24; p = .16, d = .35). Treatment did not improve physical health-related QoL over time (F(2, 202) = 1.01, p = .37) nor was there a significant interaction (F(4, 202) = .46, p = .76). Conclusion These findings suggest that CBT-I, particularly the CT component, may be effective in improving mental health-related QoL outcomes for older adults with insomnia. In contrast, neither CBT-I nor its component treatments were effective in improving physical health-related QoL. Support (if any) NIMHR01MH101468-01; Mental Illness Research, Education, and Clinical Center (MIRECC) at the VAPAHCS


ESC CardioMed ◽  
2018 ◽  
pp. 1754-1758
Author(s):  
Anna Strömberg

The traditional objective and often physiologically or clinically focused outcome variables fail to capture the voice of the patient and their subjective experience of how heart failure and its treatment affect their life. Health-related quality of life is an established outcome measure for assessing the subjective impact that a disease with its symptoms and consequences has on the quality of life of the affected individual. There are a number of validated generic and disease-specific instruments for measuring health-related quality of life that are getting more and more commonly used in research, quality assessment, and clinical practice. Compared to other chronic illnesses, the impact of the heart failure condition on quality of life is more prominent. The families of patients with heart failure are also affected, with their quality of life also negatively influenced. Interventions that are improving health-related quality of life in patients with heart failure are pharmacological treatment, a structural follow-up, psychoeducational interventions to support self-care, and exercise training. The goal of all heart failure treatment and care is for the patient to both live longer and live better. Despite improved treatment the prognosis for many patients with heart failure is quite poor and many patients are highly symptomatic with decreased functional status and quality of life. Many patients attach more weight to quality of life over longevity, which further supports the belief that patients with heart failure are willing to trade time for an improvement in health status.


2020 ◽  
Author(s):  
Takashi Hatano ◽  
Yuki ohno ◽  
YU Imai ◽  
Jun Moritake ◽  
Katsuhisa Endo ◽  
...  

Abstract Background : Tuberous sclerosis complex (TSC) is a rare autosomal dominant disorder forming hamartomas throughout the body. Facial angiofibromas (FAs) occur in 75% of TSC patients, which are often enlarged, impairing the appearance of the face, and reducing the patient's quality of life (QOL). The aim of this study was to characterize the impact of topical sirolimus treatment on the health-related QOL in patients with FA associated with TSC. Methods : We investigated a total of 33 patients who received sirolimus gel treatment for FA associated with TSC and assessed the changes in the health-related QOL using the Medical Outcomes Study 36-Item Short Form (SF-36) Health Survey. SF-36 surveys were performed before and after three months of treatment. The conditions of the patients after using the sirolimus gel were categorized into the following three categories: "improved," "unchanged," and "aggravated." Adverse events were investigated using the CTCAE v5.0-JCOG. Results : After 3 months of sirolimus gel treatment, three scale scores of the SF-36, vitality (VT), social function (SF), and mental health (MH), were significantly improved compared to before the treatment. The VT and SF in patients who had improved FA were significantly better than those in the other patients. There were no significant differences in any scale scores between patients with and without adverse events at three months after the initiation of sirolimus gel treatment. Conclusions : This is the first report regarding improved health-related quality of life in patients treated with sirolimus gel for FA associated with TSC by using the SF-36. The three scale scores associated with mental health were significantly improved compared to before the treatment. The health-related QOL in patients receiving sirolimus gel treatment is more strongly affected by the treatment efficacy than adverse events.


2020 ◽  
Author(s):  
Takashi Hatano ◽  
Yuki ohno ◽  
YU Imai ◽  
Jun Moritake ◽  
Katsuhisa Endo ◽  
...  

Abstract Background: Tuberous sclerosis complex (TSC) is a rare autosomal dominant disorder forming hamartomas throughout the body. Facial angiofibromas (FAs) occur in 75% of TSC patients, which are often enlarged, impairing the appearance of the face, and reducing the patient's quality of life (QOL). The aim of this study was to characterize the impact of topical sirolimus treatment on the health-related QOL in patients with FA associated with TSC.Methods: We investigated a total of 33 patients who received sirolimus gel treatment for FA associated with TSC and assessed the changes in the health-related QOL using the Medical Outcomes Study 36-Item Short Form (SF-36) Health Survey. SF-36 surveys were performed before and after three months of treatment. The conditions of the patients after using the sirolimus gel were categorized into the following three categories: "improved," "unchanged," and "aggravated." Adverse events were investigated using the CTCAE v5.0-JCOG.Results: The median age of the patients was 25 (range 14-55) years. After 3 months of sirolimus gel treatment, three scale scores of the SF-36, vitality (VT), social function (SF), and mental health (MH), were significantly improved compared to before the treatment. The VT and SF in patients who had improved FA were significantly better than those in the other patients. There were no significant differences in any scale scores between patients with and without adverse events at three months after the initiation of sirolimus gel treatment.Conclusions: This is the first report regarding improved health-related quality of life in patients treated with sirolimus gel for FA associated with TSC by using the SF-36. The three scale scores associated with mental health were significantly improved compared to before the treatment. The health-related QOL in patients receiving sirolimus gel treatment is more strongly affected by the treatment efficacy than adverse events. Mini-abstractSirolimus gel treatment improves the health-related QOL in patients with FA associated with TSC.


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