scholarly journals The Role of Sphingosine-1-Phosphate Transporter Spns2 in Immune System Function

2012 ◽  
Vol 189 (1) ◽  
pp. 102-111 ◽  
Author(s):  
Anastasia Nijnik ◽  
Simon Clare ◽  
Christine Hale ◽  
Jing Chen ◽  
Claire Raisen ◽  
...  
Keyword(s):  
Immune System ◽  
Phosphate Transporter ◽  
System Function ◽  
Immune System Function ◽  
Sphingosine 1 Phosphate

scholarly journals The role of Lactic Acid Bacteria in Gut Microbiota and Mucosal Immune System

2021 ◽  
Vol 2 (3) ◽  
pp. 3818-3825
Author(s):  
Siyu Lu
Keyword(s):  
Immune System ◽  
Gut Microbiota ◽  
Dietary Supplementation ◽  
Fermented Food ◽  
Natural Food ◽  
System Function ◽  
Beneficial Effects ◽  
Immune System Function ◽  
Excessive Consumption

In recent years, nutritionists and microbiologists have paid more attention to the utilization of dietary supplementation produced by natural food resources, to improve the immune system function of the human and animals. People are more willing to obtain nature supplementations due to the growing awareness of food safety, and the side effects of excessive consumption of manufactured supplements. Fermented food are introduced to provide beneficial effects on health because of the characteristics of LAB, which are temporary integrative microorganisms in the intestinal microbiota. And they could not only balance the micro-ecosystem of the host by secreting microbiome, but also enhance the beneficial properties of autonomous microorganisms. This review aims to discuss the of LAB yogurt to the gut microbiota based on recent research.

scholarly journals Incomplete Inhibition of Sphingosine 1-Phosphate Lyase Modulates Immune System Function yet Prevents Early Lethality and Non-Lymphoid Lesions

PLoS ONE ◽  
2009 ◽  
Vol 4 (1) ◽  
pp. e4112 ◽  
Author(s):  
Peter Vogel ◽  
Michael S. Donoviel ◽  
Robert Read ◽  
Gwenn M. Hansen ◽  
Jill Hazlewood ◽  
...  
Keyword(s):  
Immune System ◽  
System Function ◽  
Immune System Function ◽  
Sphingosine 1 Phosphate ◽  
Early Lethality

scholarly journals The role of HIV-infection in the development risk factors of cardiovascular diseases in naive HIV-infected patients and HIV-infected patients on antiretroviral therapy

2014 ◽  
Vol 5 (2) ◽  
pp. 36-40
Author(s):  
I. I Chukayeva ◽  
I. V Komarova ◽  
A. V Kravchenko ◽  
T. E Kushakova
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Immune System ◽  
Cardiovascular Diseases ◽  
Modern World ◽  
System Function ◽  
High Cardiovascular Risk ◽  
Immune System Function ◽  
Development Risk

Cardiovascular diseases are one of the main reasons of death in the modern world. Risk factor conception is emphasized in theirs prophylaxis. Nowadays besides risk factors mark out so called «special» population groups in which prophylactic actions school be more aggressive because of high cardiovascular risk. One of such groups is HIV-infected patients. It well known that among them the prevalence of traditional and «new» risk factors is much higher. At the same time in spite of the fact that there are a lot of trials it is lack of evidence about cardiovascular risk factors in HIV-infected patients with the saved immune system function as in «naive», so in antiretroviral treated patients. The aim of our investigation was to evaluate range of express traditional and «new» risk factors in «naive» and antiretroviral treated HIV-infected patients with the saved immune system function.

scholarly journals Acetylation in Tumor Immune Evasion Regulation

2021 ◽  
Vol 12 ◽  
Author(s):  
Jun Lu ◽  
Xiang He ◽  
Lijuan Zhang ◽  
Ran Zhang ◽  
Wenzheng Li
Keyword(s):  
Immune System ◽  
Tumor Immunity ◽  
Immune Evasion ◽  
Tumor Suppressors ◽  
Pathological Process ◽  
System Function ◽  
Comprehensive Understanding ◽  
Tumor Immune Evasion ◽  
Immune System Function

Acetylation is considered as one of the most common types of epigenetic modifications, and aberrant histone acetylation modifications are associated with the pathological process of cancer through the regulation of oncogenes and tumor suppressors. Recent studies have shown that immune system function and tumor immunity can also be affected by acetylation modifications. A comprehensive understanding of the role of acetylation function in cancer is essential, which may help to develop new therapies to improve the prognosis of cancer patients. In this review, we mainly discussed the functions of acetylase and deacetylase in tumor, immune system and tumor immunity, and listed the information of drugs targeting these enzymes in tumor immunotherapy.

Modulatory Role of the Epinergic System in the Neuroendocrine-Immune System Function

2000 ◽  
Vol 8 (2) ◽  
pp. 98-106 ◽  
Author(s):  
Andrés Giovambattista ◽  
Andrea N. Chisari ◽  
Rolf C. Gaillard ◽  
Eduardo Spinedi
Keyword(s):  
Immune System ◽  
System Function ◽  
Immune System Function

scholarly journals Cytokine storm in aged people with CoV-2: possible role of vitamins as therapy or preventive strategy

2020 ◽  
Vol 32 (10) ◽  
pp. 2115-2131
Author(s):  
Sirio Fiorino ◽  
Claudio Gallo ◽  
Maddalena Zippi ◽  
Sergio Sabbatani ◽  
Roberto Manfredi ◽  
...  
Keyword(s):  
Immune System ◽  
Autoimmune Diseases ◽  
Elderly Subjects ◽  
Preventive Strategy ◽  
System Function ◽  
Proinflammatory Response ◽  
Aged People ◽  
Immune System Dysfunction ◽  
Immune System Function

Abstract Background In December 2019, a novel human-infecting coronavirus, SARS-CoV-2, had emerged. The WHO has classified the epidemic as a “public health emergency of international concern”. A dramatic situation has unfolded with thousands of deaths, occurring mainly in the aged and very ill people. Epidemiological studies suggest that immune system function is impaired in elderly individuals and these subjects often present a deficiency in fat-soluble and hydrosoluble vitamins. Methods We searched for reviews describing the characteristics of autoimmune diseases and the available therapeutic protocols for their treatment. We set them as a paradigm with the purpose to uncover common pathogenetic mechanisms between these pathological conditions and SARS-CoV-2 infection. Furthermore, we searched for studies describing the possible efficacy of vitamins A, D, E, and C in improving the immune system function. Results SARS-CoV-2 infection induces strong immune system dysfunction characterized by the development of an intense proinflammatory response in the host, and the development of a life-threatening condition defined as cytokine release syndrome (CRS). This leads to acute respiratory syndrome (ARDS), mainly in aged people. High mortality and lethality rates have been observed in elderly subjects with CoV-2-related infection. Conclusions Vitamins may shift the proinflammatory Th17-mediated immune response arising in autoimmune diseases towards a T-cell regulatory phenotype. This review discusses the possible activity of vitamins A, D, E, and C in restoring normal antiviral immune system function and the potential therapeutic role of these micronutrients as part of a therapeutic strategy against SARS-CoV-2 infection.

scholarly journals The role of Lactic Acid Bacteria in Gut Microbiota and Mucosal Immune System

2021 ◽  
Vol 271 ◽  
pp. 03075
Author(s):  
Siyu Lu
Keyword(s):  
Immune System ◽  
Gut Microbiota ◽  
Dietary Supplementation ◽  
Fermented Food ◽  
Natural Food ◽  
System Function ◽  
Beneficial Effects ◽  
Immune System Function ◽  
Excessive Consumption

In recent years, nutritionists and microbiologists have paid more attention to the utilization of dietary supplementation produced by natural food resources, to improve the immune system function of the human and animals. People are more willing to obtain nature supplementations due to the growing awareness of food safety, and the side effects of excessive consumption of manufactured supplements. Fermented food are introduced to provide beneficial effects on health because of the characteristics of LAB, which are temporary integrative microorganisms in the intestinal microbiota. And they could not only balance the micro-ecosystem of the host by secreting microbiome, but also enhance the beneficial properties of autonomous microorganisms. This review aims to discuss the of LAB yogurt to the gut microbiota based on recent research.

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