scholarly journals The role of HIV-infection in the development risk factors of cardiovascular diseases in naive HIV-infected patients and HIV-infected patients on antiretroviral therapy

2014 ◽  
Vol 5 (2) ◽  
pp. 36-40
Author(s):  
I. I Chukayeva ◽  
I. V Komarova ◽  
A. V Kravchenko ◽  
T. E Kushakova

Cardiovascular diseases are one of the main reasons of death in the modern world. Risk factor conception is emphasized in theirs prophylaxis. Nowadays besides risk factors mark out so called «special» population groups in which prophylactic actions school be more aggressive because of high cardiovascular risk. One of such groups is HIV-infected patients. It well known that among them the prevalence of traditional and «new» risk factors is much higher. At the same time in spite of the fact that there are a lot of trials it is lack of evidence about cardiovascular risk factors in HIV-infected patients with the saved immune system function as in «naive», so in antiretroviral treated patients. The aim of our investigation was to evaluate range of express traditional and «new» risk factors in «naive» and antiretroviral treated HIV-infected patients with the saved immune system function.

2021 ◽  
Vol 2 (3) ◽  
pp. 3818-3825
Author(s):  
Siyu Lu

In recent years, nutritionists and microbiologists have paid more attention to the utilization of dietary supplementation produced by natural food resources, to improve the immune system function of the human and animals. People are more willing to obtain nature supplementations due to the growing awareness of food safety, and the side effects of excessive consumption of manufactured supplements. Fermented food are introduced to provide beneficial effects on health because of the characteristics of LAB, which are temporary integrative microorganisms in the intestinal microbiota. And they could not only balance the micro-ecosystem of the host by secreting microbiome, but also enhance the beneficial properties of autonomous microorganisms. This review aims to discuss the of LAB yogurt to the gut microbiota based on recent research.


Author(s):  
Lucas Z. Randimbinirina ◽  
Fanomezantsoa H. Randrianandrianina ◽  
Tsirimalala Rajaobelison ◽  
Jean Claude A. Rakotoarisoa ◽  
Agnes M. L. Ravalisoa

Background: Cardiovascular disease (CVD) is the primary cause of morbidity and premature mortality in chronic kidney disease (CKD). The aim of this study was to assess the frequency of cardiovascular disease and cardiovascular risk in haemodialysis population for chronic kidney disease.Methods: This was a retrospective and descriptive study for a period of 4 years from January 2016 to December 2019, performed at hemodialysis unit in Soavinandriana Hospital Center Antananarivo, including all patients, following regular hemodialysis for chronic renal failure. Demographic data, cardiovascular disease, cardiovascular risk factors, aetiology of nephropathy, haemoglobin <11 g/dl, phosphocalcic metabolism disorders and uricemia were analyzed.Results: Seventy-six patients were recorded, including 46 males (60.52%) and were women (39.47%). The average age was 59.98 years old. The risk factors of cardiovascular disease were smoking (22.36%), diabetes mellitus (46.05%), high blood pressure (71.05%), dyslipidemia (47.36%) and obesity (11.84%). Fifty-eight patients (76.31%) had a high cardiovascular risk factor. Seventy patients (22.36%) had had a history of cardiovascular diseases. Fifty-nine patients had a haemoglobin concentration under 11 g/dl (77.63%). There were 23 cases of hypocalcemia (30.26%), 22 cases of hyperphosphatemia (28.94%) and 37 cases of hyperuricemia (48.68%).Conclusions: There was a high cardiovascular risk factor in this study population. Early detection of cardiovascular diseases should be done in patients who have a high-risk factor of cardiovascular disease to decrease the mortality rate in chronic kidney diseases population. The appropriate management of modifiable risk factors is important to improve the survival of this study patients.


2021 ◽  
Vol 6 (1) ◽  
pp. 50-53
Author(s):  
Anatolii O. Rubanenko ◽  
Olesya A. Rubanenko ◽  
Vladislav A. Dyachkov ◽  
Yurii V. Shchukin ◽  
Konstantin M. Ivanov

Objectives to evaluate the occurrence of the main cardiovascular risk factors in medical students. Material and methods. The MMM-18 registry included 177 students of Samara State Medical University with mean age of 21.0 years. All the students filled in a survey form anonymously, where they stated their age, gender, height and weight, smoking status (yes or no), alcohol consumption (never, once a week, regularly) and also known cardiovascular diseases (coronary heart disease, stroke) and diabetes mellitus. Results and Discussion. The study confirmed the important role of conventional cardiovascular risk factors such as smoking, high body mass index, elevated blood pressure. These findings support the necessity of periodical screening of medical students in order to timely detect and correct the above-mentioned risk factors.


2021 ◽  
Vol 93 (1) ◽  
pp. 79-83
Author(s):  
Natalia B. Lebedeva ◽  
Vladimir V. Hoffman

The literature review presents novel data on the prevalence of age-related hypogonadism and its relationship with aging, its impact on the circulatory system and cardiovascular diseases. This review summarizes the methods for diagnosing age-related hypogonadism, its association with traditional cardiovascular risk factors such as dyslipidemia, insulin resistance and diabetes mellitus, obesity, arterial hypertension. The mechanisms of the possible direct effect of testosterone on endothelium and vascular tone, the role of hormone replacement therapy as a way of preventing cardiovascular diseases are discussed.


2012 ◽  
Vol 189 (1) ◽  
pp. 102-111 ◽  
Author(s):  
Anastasia Nijnik ◽  
Simon Clare ◽  
Christine Hale ◽  
Jing Chen ◽  
Claire Raisen ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Jun Lu ◽  
Xiang He ◽  
Lijuan Zhang ◽  
Ran Zhang ◽  
Wenzheng Li

Acetylation is considered as one of the most common types of epigenetic modifications, and aberrant histone acetylation modifications are associated with the pathological process of cancer through the regulation of oncogenes and tumor suppressors. Recent studies have shown that immune system function and tumor immunity can also be affected by acetylation modifications. A comprehensive understanding of the role of acetylation function in cancer is essential, which may help to develop new therapies to improve the prognosis of cancer patients. In this review, we mainly discussed the functions of acetylase and deacetylase in tumor, immune system and tumor immunity, and listed the information of drugs targeting these enzymes in tumor immunotherapy.


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