scholarly journals Diagnostic Value of Transbronchial Lung Biopsy: Including Diagnostic Yield According to Tumor-bronchus Relationship

2000 ◽  
Vol 48 (4) ◽  
pp. 438
Author(s):  
Tae Kyong Kang ◽  
Seung Lck Cha ◽  
Jae Yong Park ◽  
Sang Chul Chae ◽  
Chang Ho Kim ◽  
...  
Keyword(s):  
Lung Biopsy ◽  
Diagnostic Yield ◽  
Diagnostic Value ◽  
Transbronchial Lung Biopsy

scholarly journals Factors associated with the diagnostic yield of computed tomography-guided transbronchial lung biopsy

2017 ◽  
Vol 8 (3) ◽  
pp. 153-158 ◽  
Author(s):  
Seon Cheol Park ◽  
Cheong Ju Kim ◽  
Chang Hoon Han ◽  
Sun Min Lee
Keyword(s):  
Computed Tomography ◽  
Lung Biopsy ◽  
Diagnostic Yield ◽  
Transbronchial Lung Biopsy ◽  
Factors Associated

Efficacy of 67Ga-Scintigraphy in Predicting the Diagnostic Yield of Transbronchial Lung Biopsy in Pulmonary Sarcoidosis

CHEST Journal ◽  
1982 ◽  
Vol 82 (1) ◽  
pp. 7-9 ◽  
Author(s):  
Richard S. Ackart ◽  
Thomas L. Munzel ◽  
James J. Rodriguez ◽  
Charles J. Donlan ◽  
Ronald J. Klayton ◽  
...  
Keyword(s):  
Lung Biopsy ◽  
Diagnostic Yield ◽  
Pulmonary Sarcoidosis ◽  
Transbronchial Lung Biopsy ◽  
67Ga Scintigraphy

scholarly journals Integration of transbronchial cryobiopsy into multidisciplinary board decision: a single center analysis of one hundred consecutive patients with interstitial lung disease

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Katrin E. Hostettler ◽  
Michael Tamm ◽  
Lukas Bubendorf ◽  
Peter Grendelmeier ◽  
Kathleen Jahn ◽  
...  
Keyword(s):  
Clinical Data ◽  
Lung Biopsy ◽  
Lung Diseases ◽  
Diagnostic Yield ◽  
Usual Interstitial Pneumonia ◽  
Diagnostic Value ◽  
Interstitial Lung Diseases ◽  
Histological Findings ◽  
Forceps Biopsy ◽  
Consensus Diagnosis

Abstract Background Transbronchial cryobiopsy in the evaluation of patients with interstitial lung diseases (ILD) is expected to reduce the need for surgical lung biopsy (SLB). Objective To evaluate the diagnostic value of cryobiopsy in combination with bronchoalveolar lavage (BAL), radiologic and clinical data in patients with ILD. Methods Between 08/15 and 01/20 patients with ILD underwent cryobiopsy if they: did not have (i) an usual interstitial pneumonia (UIP)-pattern on CT, (ii) predominant ground-glass opacities suggesting alveolitis, (iii) findings suggestive of sarcoidosis on CT, or if they had (i) a CT showing UIP-pattern, but had findings suggesting alternative diagnosis than idiopathic pulmonary fibrosis (IPF), or (ii) had previous non-diagnostic conventional transbronchial forceps biopsy. Histological findings were integrated into the multidisciplinary team discussion (MDTD) and a diagnostic consensus was sought. Results One hundred patients underwent cryobiopsy. In 88/100 patients, cryobiopsy was representative with diagnostic findings in 45/88 and non-specific histological findings in 43/88 patients. In 25/43 with non-specific findings, a consensus diagnosis was reached after MDTD integrating BAL, radiologic and clinical data; eight of the remaining 18 patients with non-specific findings were referred to SLB. In 12/100 patients cryobiopsy was not representative and three of these patients were also referred to SLB. In 7/11 patients (64%) SLB was diagnostic. Complications of cryobiopsy included pneumothorax (14%) and locally controlled bleeding (24%). Conclusions The diagnostic yield of cryobiopsy was 70%:45% of cryobiopsies were diagnostic based on histology alone and an additional 25% provided non-specific, but valuable findings allowing a consensus diagnosis after MDTD. Our data demonstrate that the diagnostic value of cryobiopsy is high if combined with BAL, radiologic and clinical data.

scholarly journals The value of transbronchial lung biopsy in the diagnosis of lymphangioleiomyomatosis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wenshuai Xu ◽  
Han Cui ◽  
Hongrui Liu ◽  
Ruie Feng ◽  
Xinlun Tian ◽  
...  
Keyword(s):  
Lung Biopsy ◽  
Diagnostic Value ◽  
Transbronchial Lung Biopsy ◽  
Safe Procedure ◽  
Telephone Interviews ◽  
Positive Rate ◽  
Grade Ii ◽  
The Difference ◽  
Diffuse Lung ◽  
Probable Diagnosis

Abstract Background Transbronchial lung biopsy (TBLB) in the diagnosis of lymphangioleiomyomatosis (LAM) is not a common approach, although TBLB is often performed in diffuse lung diseases. We aimed to examine the diagnostic value and safety of TBLB in LAM patients based on the data collected in our center. Methods We reviewed LAM patients registered in our LAM Clinic from December 8, 2006, to December 31, 2019. All patients with definite or probable diagnosis of LAM who had been examined using TBLB were included. All available pathology slides were reviewed by an experienced LAM pathologist. All complications were reviewed by the medical records and confirmed using telephone interviews. Results The pathology results of 86 patients (including 74 definite LAM and 12 probable LAM) were available. The positive rate of TBLB in LAM patients was 49/86 (57.0%). The positive rates of SMA, HMB-45, ER, and PR in LAM patients were 97.6%, 93%, 84.6%, and 78.4% respectively. The positive rate of TBLB was 40%, 60% and 60.8% in patients with CT Grade I, Grade II, and Grade III respectively, and the difference was not significant. Patients who had 3–4 or 5–6 biopsied specimens had a higher rate of diagnosis than those with 1–2 biopsied specimens. Four patients (5.6%) reported pneumothorax. No major hemoptysis was reported. Conclusions TBLB is a feasible and safe procedure for obtaining a pathological diagnosis of LAM. Taking more than 2 samples during the biopsy procedure increased the rate of diagnosis.

scholarly journals Diagnostic Value of Virtual Bronchoscopic Navigation Combined With Endobronchial Ultrasound Guided Transbronchial Lung Biopsy for Peripheral Pulmonary Lesions

2021 ◽  
Vol 20 ◽  
pp. 153303382198999
Author(s):  
Chunhua Xu ◽  
Yan Wang ◽  
Li Li ◽  
Qi Yuan ◽  
Yuchao Wang ◽  
...  
Keyword(s):  
Lung Biopsy ◽  
Diagnostic Yield ◽  
Operation Time ◽  
Transbronchial Lung Biopsy ◽  
Endobronchial Ultrasound ◽  
Ultrasound Guided ◽  
Pulmonary Lesions ◽  
X Ray ◽  
Significant Difference ◽  
Peripheral Pulmonary Lesions

Objective: X-ray guided transbronchial ultrasound-guided transbronchial lung biopsy (EBUS-TBLB) can improve the diagnostic yield of peripheral pulmonary lesions (PPLs), but it needs special requirements. The purpose of this study was to investigate the clinical value of virtual bronchoscopy navigation (VBN) combined with EBUS-TBLB in the diagnosis of PPLs without X-ray guidance. Methods: The 105 patients with PPLs underwent EBUS-TBLB with or without VBN randomly. The diagnostic yield, the operation time and complications were evaluated in the 2 groups. Results: No significant difference was found between the VBN+EBUS group and the EBUS group (76.0% vs. 65.5%, P = 0.287). The operation time of VBN+EBUS group was significantly shorter than that of EBUS group (20.6 ± 12.8 min vs. 28.6 ± 14.3 min, P = 0.023). No severe procedure related complications occurred. Conclusions: VBN can shorten the operation time. The combination of VBN and EBUS-TBLB is a safe and effective diagnosis technique for PPLs.

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