The Determination of Sex and Polymorphism in Microevolution

1964 ◽  
Vol 96 (1-2) ◽  
pp. 418-428 ◽  
Author(s):  
G. Stehr
Keyword(s):  
Natural Selection ◽  
Larval Development ◽  
Selection Pressure ◽  
The Other ◽  
Quantitative Character ◽  
Short Term ◽  
Balance System ◽  
Wing Colour ◽  
Adult Wing

AbstractEnvironmental instabilities may be grouped into three broad categories each with different conseqences for the organism which has to survive the stress of these instabilities. On one side are irreversible changes of the environment which will lead to complete adaptive compliance or conformity of the population, brought about by natural selection. On the other side are short-term recurrent instabilities, fluctuations, or oscillations; if their cycle is short enough so that all phases are experienced by all individuals of each generation, natural selection will promote the ability of each individual to withstand the whole range of environmental recurrent fluctuations. Between these extremes are recurrent instabilities that are not experienced by all individuals, or by each generation; here natural selection will evolve mechanisms that prevent the population from conforming with any temporary selection pressure. Polymorphism is such a mechanism, specifically polymorphism based on a gene potency balance system modelled on the same principles as the system that determines sex, the most common example of polymorphism. Instances of such polymorphism in a genus of tortricid moths include haemolymph pigment, adult wing colour, and rate of larval development. The latter exemplifies polymorphism of a quantitative character.

scholarly journals Clinical implications of glucocorticoid receptor studies in childhood acute lymphoblastic leukemia

Blood ◽  
1980 ◽  
Vol 56 (6) ◽  
pp. 1036-1040 ◽  
Author(s):  
R Mastrangelo ◽  
R Malandrino ◽  
R Riccardi ◽  
P Longo ◽  
FO Ranelletti ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Glucocorticoid Receptor ◽  
Glucocorticoid Receptors ◽  
Lymphoblastic Leukemia ◽  
Poor Response ◽  
The Other ◽  
Clinical Implications ◽  
Short Term

Abstract We have performed in parallel, in 19 children with acute lymphoblastic leukemia, a quantitative determination of glucocorticoid levels, in vitro steroid induced inhibition of nucleic acid precursors, and a short-term clinical trial of corticosteroids alone, before the treatment was given, which included corticosteroids and other drugs. From our results it appears that high glucocorticoid receptor levels in acute lymphoblastic leukemia of children do not guarantee a clinical response to corticosteroids. On the other hand, glucocorticoid receptors may turn out to be of value in predicting a poor response to corticosteroids only if their levels are considerably low.

scholarly journals Clinical implications of glucocorticoid receptor studies in childhood acute lymphoblastic leukemia

Blood ◽  
1980 ◽  
Vol 56 (6) ◽  
pp. 1036-1040 ◽  
Author(s):  
R Mastrangelo ◽  
R Malandrino ◽  
R Riccardi ◽  
P Longo ◽  
FO Ranelletti ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Glucocorticoid Receptor ◽  
Glucocorticoid Receptors ◽  
Lymphoblastic Leukemia ◽  
Poor Response ◽  
The Other ◽  
Clinical Implications ◽  
Short Term

We have performed in parallel, in 19 children with acute lymphoblastic leukemia, a quantitative determination of glucocorticoid levels, in vitro steroid induced inhibition of nucleic acid precursors, and a short-term clinical trial of corticosteroids alone, before the treatment was given, which included corticosteroids and other drugs. From our results it appears that high glucocorticoid receptor levels in acute lymphoblastic leukemia of children do not guarantee a clinical response to corticosteroids. On the other hand, glucocorticoid receptors may turn out to be of value in predicting a poor response to corticosteroids only if their levels are considerably low.

Determination of Bismuth in Body Tissues and Fluids After Administration of Controlled Doses

1972 ◽  
Vol 55 (3) ◽  
pp. 639-642
Author(s):  
Robert J Hall ◽  
Theodore Farber
Keyword(s):  
Water Soluble ◽  
The Other ◽  
Ammonium Citrate ◽  
Acid Digestion ◽  
Short Term ◽  
Body Tissues ◽  
Short Term Exposure ◽  
Soluble Compound ◽  
Bismuth Salts

Abstract Controlled amounts of water-soluble and water-insoluble bismuth salts were administered to dogs. Body tissues and fluids were examined for resultant bismuth residues by an acid digestion-atomic absorption procedure. The method was shown to recover bismuth added to body tissues and fluids; the acid digestion released the bismuth residues almost completely. the highest levels of bismuth were found in the kidneys: about 10 ppm bismuth resulted from the administration of the waterinsoluble compound, bismuth subcarbonale, and about 60 ppm from the soluble compound, bismuth ammonium citrate . The levels of bismuth found in the urine were higher than those found in the other body tissues and the blood serum, but were still relatively low. No pathological manifestations were observed after short-term exposure to bismuth.

Coattail Voting in Recent Presidential Elections

1983 ◽  
Vol 77 (2) ◽  
pp. 407-419 ◽  
Author(s):  
Randall L. Calvert ◽  
John A. Ferejohn
Keyword(s):  
Survey Data ◽  
Presidential Election ◽  
Presidential Elections ◽  
The Other ◽  
Short Term ◽  
Presidential Candidates ◽  
Other Hand ◽  
Congressional Representation

This article presents a method for analyzing the extent and strength of coattail voting in presidential elections. This method allows the authors to estimate the magnitude of coattail voting and then to decompose this estimate into more “basic” elements. Estimates are given for presidential elections beginning with 1956.The determination of the coattail vote and its decomposition depend on the theory of the voting decision that is assumed. In this article we present a model of vote determination that is similar in most respects to the traditional SRC model; the vote for congressional representation in a presidential election year is determined jointly by partisan affiliation, attitudes toward the presidential candidates, and local forces unique to the congressional race (such as may be captured by an incumbency variable). This model permits the separate estimation of the strength of short-term forces and of the efficiency of the presidential coattails.Application of the model to survey data since 1956 indicates that efficiency of presidential coattails has declined during this period. Furthermore, the 1980 election does not appear to be an exception to this trend. On the other hand there has not been any particular trend in the strength of short-term forces during this period; instead events peculiar to the context of a specific election generate short-term forces at the level of the presidential election, but the degree to which these forces are carried over to local races seems to have declined.

Determination of the lattice translation across {110} APBs in GaAs

1988 ◽  
Vol 46 ◽  
pp. 600-601
Author(s):  
D.R. Rasmussen ◽  
N.-H. Cho ◽  
C.B. Carter
Keyword(s):  
Grain Boundaries ◽  
Lower Energy ◽  
Antiphase Boundary ◽  
The Other ◽  
Boundary Structure ◽  
Interface Plane ◽  
Inversion Symmetry ◽  
High Angle ◽  
Equilibrium Distance

Domains in GaAs can exist which are related to one another by the inversion symmetry, i.e., the sites of gallium and arsenic in one domain are interchanged in the other domain. The boundary between these two different domains is known as an antiphase boundary [1], In the terminology used to describe grain boundaries, the grains on either side of this boundary can be regarded as being Σ=1-related. For the {110} interface plane, in particular, there are equal numbers of GaGa and As-As anti-site bonds across the interface. The equilibrium distance between two atoms of the same kind crossing the boundary is expected to be different from the length of normal GaAs bonds in the bulk. Therefore, the relative position of each grain on either side of an APB may be translated such that the boundary can have a lower energy situation. This translation does not affect the perfect Σ=1 coincidence site relationship. Such a lattice translation is expected for all high-angle grain boundaries as a way of relaxation of the boundary structure.

Determination of the Burgers vector of a dislocation in a Fe-Mn alloy by weak-beam image in HVEM

1978 ◽  
Vol 36 (1) ◽  
pp. 330-331
Author(s):  
Y. Ishida ◽  
H. Ishida ◽  
K. Kohra ◽  
H. Ichinose
Keyword(s):  
High Order ◽  
Simulation Technique ◽  
The Other ◽  
Image Simulation ◽  
Diffraction Vector ◽  
Burgers Vector ◽  
Weak Beam ◽  
Beam Image ◽  
Edge Component

IntroductionA simple and accurate technique to determine the Burgers vector of a dislocation has become feasible with the advent of HVEM. The conventional image vanishing technique(1) using Bragg conditions with the diffraction vector perpendicular to the Burgers vector suffers from various drawbacks; The dislocation image appears even when the g.b = 0 criterion is satisfied, if the edge component of the dislocation is large. On the other hand, the image disappears for certain high order diffractions even when g.b ≠ 0. Furthermore, the determination of the magnitude of the Burgers vector is not easy with the criterion. Recent image simulation technique is free from the ambiguities but require too many parameters for the computation. The weak-beam “fringe counting” technique investigated in the present study is immune from the problems. Even the magnitude of the Burgers vector is determined from the number of the terminating thickness fringes at the exit of the dislocation in wedge shaped foil surfaces.

A Bird in the Hand Isn’t Good for Long

2018 ◽  
Vol 65 (1) ◽  
pp. 23-31 ◽  
Author(s):  
Stefan Scherbaum ◽  
Simon Frisch ◽  
Maja Dshemuchadse
Keyword(s):  
Decision Making ◽  
Cognitive Control ◽  
The Other ◽  
Decision Task ◽  
Short Term ◽  
Additional Time ◽  
Control Processes ◽  
Folk Wisdom ◽  
Study Participants ◽  
Insight Into

Abstract. Folk wisdom tells us that additional time to make a decision helps us to refrain from the first impulse to take the bird in the hand. However, the question why the time to decide plays an important role is still unanswered. Here we distinguish two explanations, one based on a bias in value accumulation that has to be overcome with time, the other based on cognitive control processes that need time to set in. In an intertemporal decision task, we use mouse tracking to study participants’ responses to options’ values and delays which were presented sequentially. We find that the information about options’ delays does indeed lead to an immediate bias that is controlled afterwards, matching the prediction of control processes needed to counter initial impulses. Hence, by using a dynamic measure, we provide insight into the processes underlying short-term oriented choices in intertemporal decision making.

Procedures for the Quantitative Determination of Autoprothrombin C

1962 ◽  
Vol 08 (03) ◽  
pp. 434-441 ◽  
Author(s):  
Edmond R Cole ◽  
Ewa Marciniak ◽  
Walter H Seegers
Keyword(s):  
Quantitative Determination ◽  
Plasma Sample ◽  
Quantitative Measure ◽  
The Other ◽  
Clotting Time ◽  
Bovine Plasma ◽  
Autoprothrombin C

SummaryTwo quantitative procedures for autoprothrombin C are described. In one of these purified prothrombin is used as a substrate, and the activity of autoprothrombin C can be measured even if thrombin is in the preparation. In this procedure a reaction mixture is used wherein the thrombin titer which develops in 20 minutes is proportional to the autoprothrombin C in the reaction mixture. A unit is defined as the amount which will generate 70 units of thrombin in the standardized reaction mixture. In the other method thrombin interferes with the result, because a standard bovine plasma sample is recalcified and the clotting time is noted. Autoprothrombin C shortens the clotting time, and the extent of this is a quantitative measure of autoprothrombin C activity.

Determination of Factor XIII Activity and of Factor XIII Inhibitors Using an Ammonium-Sensitive Electrode

1983 ◽  
Vol 50 (02) ◽  
pp. 563-566 ◽  
Author(s):  
P Hellstern ◽  
K Schilz ◽  
G von Blohn ◽  
E Wenzel
Keyword(s):  
Factor Xiii ◽  
Normal Subjects ◽  
The Other ◽  
Activity Measurement ◽  
Factor Xiii Deficiency ◽  
Assay Procedure ◽  
Stabilization Factor ◽  
Release Method ◽  
Sensitive Electrode

SummaryAn assay for rapid factor XIII activity measurement has been developed based on the determination of the ammonium released during fibrin stabilization. Factor XIII was activated by thrombin and calcium. Ammonium was measured by an ammonium-sensitive electrode. It was demonstrated that the assay procedure yields accurate and precise results and that factor XIII-catalyzed fibrin stabilization can be measured kinetically. The amount of ammonium released during the first 90 min of fibrin stabilization was found to be 7.8 ± 0.5 moles per mole fibrinogen, which is in agreement with the findings of other authors. In 15 normal subjects and in 15 patients suffering from diseases with suspected factor XIII deficiency there was a satisfactory correlation between the results obtained by the “ammonium-release-method”, Bohn’s method, and the immunological assay (r1 = 0.65; r2= 0.70; p<0.01). In 3 of 5 patients with paraproteinemias the values of factor XIII activity determined by the ammonium-release method were markedly lower than those estimated by the other methods. It could be shown that inhibitor mechanisms were responsible for these discrepancies.

Hidden “holes” in the capital of banks and the supply of credit to the real sector of economy

2018 ◽  
pp. 49-68 ◽  
Author(s):  
M. E. Mamonov
Keyword(s):  
Credit Risk ◽  
The Other ◽  
Real Sector ◽  
Capital Management ◽  
Loan Loss ◽  
Short Term ◽  
The Real ◽  
Ex Post ◽  
The One

Our analysis documents that the existence of hidden “holes” in the capital of not yet failed banks - while creating intertemporal pressure on the actual level of capital - leads to changing of maturity of loans supplied rather than to contracting of their volume. Long-term loans decrease, whereas short-term loans rise - and, what is most remarkably, by approximately the same amounts. Standardly, the higher the maturity of loans the higher the credit risk and, thus, the more loan loss reserves (LLP) banks are forced to create, increasing the pressure on capital. Banks that already hide “holes” in the capital, but have not yet faced with license withdrawal, must possess strong incentives to shorten the maturity of supplied loans. On the one hand, it raises the turnovers of LLP and facilitates the flexibility of capital management; on the other hand, it allows increasing the speed of shifting of attracted deposits to loans to related parties in domestic or foreign jurisdictions. This enlarges the potential size of ex post revealed “hole” in the capital and, therefore, allows us to assume that not every loan might be viewed as a good for the economy: excessive short-term and insufficient long-term loans can produce the source for future losses.

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