scholarly journals Serum Soluble Interleukin-2 Receptor is Increased in Malnourished and Immunosuppressed Patients With Gastric and Colorectal Cancer: Possible Influence of Myeloid-Derived Suppressor Cells

2012 ◽  
Author(s):  
Gonda
Keyword(s):  
Colorectal Cancer ◽  
Interleukin 2 ◽  
Suppressor Cells ◽  
Myeloid Derived Suppressor Cells ◽  
Interleukin 2 Receptor ◽  
Immunosuppressed Patients ◽  
Soluble Interleukin 2 Receptor

Serum Soluble Interleukin-2 Receptor in Colorectal Cancer

1994 ◽  
Vol 33 (1) ◽  
pp. 19-21 ◽  
Author(s):  
Saburo Murakami ◽  
Akira Satomi ◽  
Kiyoshi Ishida ◽  
Hideaki Murai ◽  
Yuima Okamura
Keyword(s):  
Colorectal Cancer ◽  
Interleukin 2 ◽  
Interleukin 2 Receptor ◽  
Soluble Interleukin 2 Receptor

Interleukin 2 and soluble interleukin 2-receptor secretion defect in vitro in newly diagnosed type I diabetic patients

Diabetes ◽  
1989 ◽  
Vol 38 (3) ◽  
pp. 310-315 ◽  
Author(s):  
C. Giordano ◽  
F. Panto ◽  
C. Caruso ◽  
M. A. Modica ◽  
A. M. Zambito ◽  
...  
Keyword(s):  
Interleukin 2 ◽  
Diabetic Patients ◽  
Type I ◽  
Newly Diagnosed ◽  
Interleukin 2 Receptor ◽  
Soluble Interleukin 2 Receptor

Soluble Interleukin-2 Receptor Levels in Patients With Dilated Cardiomyopathy

Circulation ◽  
1995 ◽  
Vol 91 (3) ◽  
pp. 631-634 ◽  
Author(s):  
Constantinos J. Limas ◽  
Irvin F. Goldenberg ◽  
Catherine Limas
Keyword(s):  
Dilated Cardiomyopathy ◽  
Interleukin 2 ◽  
Interleukin 2 Receptor ◽  
Soluble Interleukin 2 Receptor

Soluble Interleukin 2 Receptor in Dialyzed Patients

1998 ◽  
Vol 22 (2) ◽  
pp. 142-144 ◽  
Author(s):  
Kuo‐Hsiung Shu ◽  
Yuan‐San Lu ◽  
Chi‐Hung Cheng ◽  
Jong‐Da Lian
Keyword(s):  
Interleukin 2 ◽  
Interleukin 2 Receptor ◽  
Soluble Interleukin 2 Receptor

scholarly journals Immunomodulation by Inflammation during Liver and Gastrointestinal Tumorigenesis and Aging

2021 ◽  
Vol 22 (5) ◽  
pp. 2238
Author(s):  
Nao Nagai ◽  
Yotaro Kudo ◽  
Daisuke Aki ◽  
Hayato Nakagawa ◽  
Koji Taniguchi
Keyword(s):  
Colorectal Cancer ◽  
Chronic Inflammation ◽  
Antitumor Immunity ◽  
Suppressor Cells ◽  
Treg Cells ◽  
Cytotoxic T Cell ◽  
Myeloid Derived Suppressor Cells ◽  
Age Related ◽  
Immunosuppressive Tumor Microenvironment ◽  
Pro Inflammatory Cytokines

Chronic inflammation is thought to promote tumorigenesis and metastasis by several mechanisms, such as affecting tumor cells directly, establishing a tumor-supporting microenvironment, enhancing tumor angiogenesis, and suppressing antitumor immunity. In this review, we discuss the recent advances in our understanding of how inflammation induces the immunosuppressive tumor microenvironment, such as increasing the level of pro-inflammatory cytokines, chemokines, and immunosuppressive molecules, inducing immune checkpoint molecules and cytotoxic T-cell exhaustion, and accumulating regulatory T (Treg) cells and myeloid-derived suppressor cells (MDSCs). The suppression of antitumor immunity by inflammation is especially examined in the liver and colorectal cancer. In addition, chronic inflammation is induced during aging and causes age-related diseases, including cancer, by affecting immunity. Therefore, we also discuss the age-related diseases regulated by inflammation, especially in the liver and colon.

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