scholarly journals Exercise Training Prevents Endometrial Hyperplasia and Biomarkers for Endometrial Cancer in Rat Model of Type 1 Diabetes

2010 ◽  
Author(s):  
Muhammed Al-Jarrah
Keyword(s):  
Type 1 Diabetes ◽  
Endometrial Cancer ◽  
Exercise Training ◽  
Rat Model ◽  
Endometrial Hyperplasia

CARDIOPROTECTIVE EFFECTS OF DIALLYL TRISULFIDE IN A RAT MODEL OF TYPE-1 DIABETES MELLITUS

2018 ◽  
Vol 25 (3) ◽  
pp. 217
Author(s):  
Jovana Jeremic ◽  
Ivan Srejovic ◽  
Vladimir Zivkovic ◽  
Tamara Nikolic Turnic ◽  
Isidora Milosavljevic ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Rat Model ◽  
Diallyl Trisulfide ◽  
Cardioprotective Effects

scholarly journals The effects of exercise training versus intensive insulin treatment on skeletal muscle fibre content in type 1 diabetes mellitus rodents

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
David P. McBey ◽  
Michelle Dotzert ◽  
C. W. J. Melling
Keyword(s):  
Diabetes Mellitus ◽  
Skeletal Muscle ◽  
Type 1 Diabetes ◽  
Exercise Training ◽  
Muscle Fibre ◽  
Lipid Content ◽  
Fibre Type ◽  
Insulin Treatment ◽  
Type I

Abstract Background Intensive-insulin treatment (IIT) strategy for patients with type 1 diabetes mellitus (T1DM) has been associated with sedentary behaviour and the development of insulin resistance. Exercising patients with T1DM often utilize a conventional insulin treatment (CIT) strategy leading to increased insulin sensitivity through improved intramyocellular lipid (IMCL) content. It is unclear how these exercise-related metabolic adaptations in response to exercise training relate to individual fibre-type transitions, and whether these alterations are evident between different insulin strategies (CIT vs. IIT). Purpose: This study examined glycogen and fat content in skeletal muscle fibres of diabetic rats following exercise-training. Methods Male Sprague-Dawley rats were divided into four groups: Control-Sedentary, CIT- and IIT-treated diabetic sedentary, and CIT-exercised trained (aerobic/resistance; DARE). After 12 weeks, muscle-fibre lipids and glycogen were compared through immunohistochemical analysis. Results The primary findings were that both IIT and DARE led to significant increases in type I fibres when compared to CIT, while DARE led to significantly increased lipid content in type I fibres compared to IIT. Conclusions These findings indicate that alterations in lipid content with insulin treatment and DARE are primarily evident in type I fibres, suggesting that muscle lipotoxicity in type 1 diabetes is muscle fibre-type dependant.

scholarly journals Exercise Training Lowers Plasma Visfatin Concentrations in Patients with Type 1 Diabetes

2006 ◽  
Vol 91 (11) ◽  
pp. 4702-4704 ◽  
Author(s):  
Dominik G. Haider ◽  
Johannes Pleiner ◽  
Mario Francesconi ◽  
Günther F. Wiesinger ◽  
Markus Müller ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Exercise Training

scholarly journals Metabolic effects of duodenojejunal bypass surgery in a rat model of type 1 diabetes

2020 ◽  
Author(s):  
Roman Vangoitsenhoven ◽  
Rickesha Wilson ◽  
Gautam Sharma ◽  
Suriya Punchai ◽  
Ricard Corcelles ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Rat Model ◽  
Bypass Surgery ◽  
Metabolic Effects ◽  
Duodenojejunal Bypass

scholarly journals Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared With Type 1 Diabetes

Diabetes ◽  
2020 ◽  
Vol 69 (4) ◽  
pp. 624-633 ◽  
Author(s):  
Anne Jörns ◽  
Dirk Wedekind ◽  
Joachim Jähne ◽  
Sigurd Lenzen
Keyword(s):  
Type 1 Diabetes ◽  
Rat Model ◽  
Autoimmune Diabetes ◽  
Latent Autoimmune Diabetes
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