Telemonitoring System of Neurological Signs in a Health Telematique Network

2010 ◽  
Vol 1 (4) ◽  
pp. 14-34 ◽  
Author(s):  
Silviu Folea ◽  
Camelia Avram ◽  
Sorin Vidican ◽  
Adina Astilean

The paper presents a new, experimental, wireless tremor telemonitoring system composed of an optional variable number of portable devices integrating three-axis acceleration mini-sensors which are connected to very small dimensions acquisition systems with Wi-Fi transmission capabilities. The main advantages of the design system consist of the possibilities to monitor simultaneously many body parts of one or multiple subjects on local or more extended areas both for scheduled assessments and in an everyday life environment. Possible applications of the presented experimental system, considered as a part of a health telematic network, consist of delivering supplementary, consistent sets of data to clinicians in order to reliably assess patients’ state in home and community settings, over longer periods of time. This system consists of delivering new data necessary for differential diagnosis of different types of tremors, or to precise different stages of illness in a health telematic network. The multiple simultaneous measuring capabilities and the extended observation time period could cover eventually neglected aspects related to occasional, temporary, or an intermittent tremor. The Wi-Fi DAQ proposed system’s novelty, in contrast with existing Wi-Fi solutions, is its ultra low power Wi-Fi capability, which makes it suitable for sensing applications where battery power management is critical.

Author(s):  
Silviu Folea ◽  
Camelia Avram ◽  
Sorin Vidican ◽  
Adina Astilean

The paper presents a new, experimental, wireless tremor telemonitoring system composed of an optional variable number of portable devices integrating three-axis acceleration mini-sensors which are connected to very small dimensions acquisition systems with Wi-Fi transmission capabilities. The main advantages of the design system consist of the possibilities to monitor simultaneously many body parts of one or multiple subjects on local or more extended areas both for scheduled assessments and in an everyday life environment. Possible applications of the presented experimental system, considered as a part of a health telematic network, consist of delivering supplementary, consistent sets of data to clinicians in order to reliably assess patients’ state in home and community settings, over longer periods of time. This system consists of delivering new data necessary for differential diagnosis of different types of tremors, or to precise different stages of illness in a health telematic network. The multiple simultaneous measuring capabilities and the extended observation time period could cover eventually neglected aspects related to occasional, temporary, or an intermittent tremor. The Wi-Fi DAQ proposed system’s novelty, in contrast with existing Wi-Fi solutions, is its ultra low power Wi-Fi capability, which makes it suitable for sensing applications where battery power management is critical.


2020 ◽  
Author(s):  
Anirban Sinha ◽  
René Lutter ◽  
Tamara Dekker ◽  
Barbara Dierdorp ◽  
Peter J. Sterk ◽  
...  

AbstractAccurate detection of human respiratory viral infections is highly topical. We investigated how strongly inflammatory biomarkers (FeNO, eosinophils, neutrophils, and cytokines in nasal lavage fluid) and lung function parameters change upon rhinovirus-16 infection, in order to explore their potential use for infection detection. To this end, within a longitudinal cohort study, healthy and mildly asthmatic volunteers were experimentally inoculated with rhinovirus-16 and time series of these parameters/biomarkers were systematically recorded and compared between the pre- and post-infection phases of the study, which lasted 2 and 1 month/s, respectively. We found that the parameters’/biomarkers’ ability to discriminate between the infected and the uninfected state varied over the observation time period. Consistently over time, the concentration of cytokines in nasal lavage fluid showed moderate to very good discrimination performance, thereby qualifying for disease progression monitoring. On the other hand, lung function and FeNO, while quickly and non-invasively measurable using cheap portable devices (e.g., at airports), performed poorly.


1989 ◽  
Vol 26 (04) ◽  
pp. 289-302
Author(s):  
A. H. B. Duffy ◽  
K. J. MacCallum

In the early stages of ship design a considerable amount of experience and knowledge is used to build and evaluate empirical models with known design relationships. However, computer-based systems which aim to assist this stage have tended to concentrate on the analytical aspects of the process and have not been successful in integrating with this expertise and benefitting from it. This paper presents some of the results of a program of research into methods and representing knowledge of empirical numerical relationships used in these early stages of the design process. The work is based on an experimental system, DESIGNER, described in earlier papers. The DESIGNER system is used to carry out a series of evaluations of design sessions, using a warship design model. By examining the progress toward a set of design goals and the classes of interactions used, an improved understanding of the requirements of an interactive numerical design system is developed. As a consequence, methods have been developed to handle approximate values and relationships, to include design margins, and to represent explicitly in the system the definition and use of goals, or design requirements. Using a design model representing a bulk carrier, the paper then presents a worked example to illustrate the use of the new numerical knowledge techniques. It is concluded that the techniques could make a useful contribution to any interactive numerical design system which aims to provide improved use of expertise.


2009 ◽  
Author(s):  
Soon-Ik Cho ◽  
Yun-Jeong Kim ◽  
Jong-Ho Lee ◽  
Kwang-Hyun Baek ◽  
Suki Kim

2020 ◽  
Vol 7 (9) ◽  
pp. 200111
Author(s):  
Pietro Morasso

This study proposes a generalization of the ankle and hip postural strategies to be applied to the large class of skills that share the same basic challenge of defeating the destabilizing effect of gravity on the basis of the same neuromotor control organization, adapted and specialized to a variable number of degrees of freedom, different body parts, different muscles and different sensory feedback channels. In all the cases, we can identify two crucial elements (the CoP, centre of pressure and the CoM, centre of mass) and the central point of the paper is that most balancing skills can be framed in the CoP–CoM interplay and can be modelled as a combination/alternation of two basic stabilization strategies: the standard well-investigated COPS (or CoP stabilization strategy, the default option), where the CoM is the controlled variable and the CoP is the control variable, and the less investigated COMS (or CoM stabilization strategy), where CoP and CoM must exchange their role because the range of motion of the CoP is strongly constrained by environmental conditions. The paper focuses on the tightrope balancing skill where sway control in the sagittal plane is modelled in terms of the COPS while the more challenging sway in the coronal plane is modelled in terms of the COMS, with the support of a suitable balance pole. Both stabilization strategies are implemented as state-space intermittent, delayed feedback controllers, independent of each other. Extensive simulations support the degree of plausibility, generality and robustness of the proposed approach.


Viruses ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 1175
Author(s):  
Anirban Sinha ◽  
René Lutter ◽  
Tamara Dekker ◽  
Barbara Dierdorp ◽  
Peter J. Sterk ◽  
...  

Accurate detection of human respiratory viral infections is highly topical. We investigated how strongly inflammatory biomarkers (FeNO, eosinophils, neutrophils, and cytokines in nasal lavage fluid) and lung function parameters change upon rhinovirus 16 infection, in order to explore their potential use for infection detection. To this end, within a longitudinal cohort study, healthy and mildly asthmatic volunteers were experimentally inoculated with rhinovirus 16, and time series of these parameters/biomarkers were systematically recorded and compared between the pre- and post-infection phases of the study, which lasted two months and one month, respectively. We found that the parameters’/biomarkers’ ability to discriminate between the infected and the uninfected state varied over the observation time period. Consistently over time, the concentration of cytokines, in nasal lavage fluid, showed moderate to very good discrimination performance, thereby qualifying for disease progression monitoring, whereas lung function and FeNO, while quickly and non-invasively measurable using cheap portable devices (e.g., at airports), performed poorly.


2011 ◽  
Vol 201-203 ◽  
pp. 1147-1150
Author(s):  
Teng Wen Chang ◽  
Sei Wo Winger Tseng

Generative design system is a complex system that often focus on the technical and complex details thus away from building a system from the product designer’s thinking patterns. In addition, by focusing on the mechanism, the system is hard to construct and difficult to use for practical situation. Horizontal/vertical design thinking patterns are often used in product design practice, thus how designers make decision affect the generation reasoning. With the cognitive design researches on design thinking patterns, two research stages (experiment and implementation) are conducted and policy/generation rules are discovered during the experiment with 30 5-year design experts as focus group. An experimental system called thinking pattern-based generation system, a.l.a. ThinkGen is developed for testing the hypothesis.


2016 ◽  
Vol 31 (4) ◽  
pp. 356-360 ◽  
Author(s):  
Tom Adams ◽  
Shripad Revankar ◽  
Peter Cabauy ◽  
Bret Elkind ◽  
Darrell Cheu

Longevity of sensors and portable devices is severely limited by temperature, chemical instability, and electrolyte leakage issues associated with conventional electrochemical batteries. Betavoltaics, which operate similar to photo voltaics, can operate in a wide temperature range safely without permanent degradation. Though not a new concept, which began in the 1950's and peaked in the mid 1970's, research has been minimal and sporadic until recent advancements in ultra-low power electronics and materialization of low power applications. The technology is rapidly maturing, generating research, and development in increasing the beta emitting source and semiconductor efficiencies. This study presents an update on betavoltaic technology, results from temperature evaluation on commercially available General Licensed betavoltaic cells, development of a hybrid system for latent and burst power, modeling and simulation techniques and results, and current and proposed research and development. Betavoltaic performance was successfully demonstrated for a wide temperature range (-30?C to 70?C). Short circuit current and open circuit voltage were used to compare electrical performance. Results indicate that the open-circuit voltage and maximum power decreased as temperature increased due to increases in the semiconductor's intrinsic carrier concentration.


Growing demand for portable devices and fast increases in complexity of chip cause power dissipation is an important parameter. Power consumption and dissipation or generations of more heat possess a restriction in the direction of the integration of more transistors. Several methods have been proposed to reduce power dissipation from system level to device level. Subthreshold circuits are widely used in more advanced applications due to ultra low-power consumption. The present work targets on construction of linear feedback shift registers (LFSR) in weak inversion region and their performance observed in terms of parameters like power delay product (PDP). In CMOS circuits subthreshold region of operation allows a low-power for ample utilizations but this advantage get with the penalty of flat speed. For the entrenched and high speed applications, improving the speed of subthreshold designs is essential. To enhance this, operate the devices at maximum current over capacitance. LFSR architectures build with various types of D flip flop and XOR gate circuits are analyzed. Circuit level Simulation is carried out using 130 nm technologies.


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