scholarly journals The bone-healing effect of a xenograft in a rat calvarial defect model

2009 ◽  
Vol 28 (4) ◽  
pp. 396-400 ◽  
Author(s):  
Hakan DEVELIOGLU ◽  
Serpil UNVER SARAYDIN ◽  
Unal KARTAL
Keyword(s):  
Bone Healing ◽  
Calvarial Defect ◽  
Defect Model ◽  
Healing Effect ◽  
Rat Calvarial Defect

scholarly journals Cell-loaded injectable gelatin/alginate/LAPONITE® nanocomposite hydrogel promotes bone healing in a critical-size rat calvarial defect model

RSC Advances ◽  
2020 ◽  
Vol 10 (43) ◽  
pp. 25652-25661
Author(s):  
Bin Liu ◽  
Junqin Li ◽  
Xing Lei ◽  
Sheng Miao ◽  
Shuaishuai Zhang ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Bone Healing ◽  
Critical Size ◽  
Nanocomposite Hydrogel ◽  
Calvarial Defect ◽  
Defect Model ◽  
Promote Cell Proliferation ◽  
Calvarial Defects ◽  
Rat Calvarial Defect

An injectable cell-laden nanocomposite hydrogel simulate natural ECM, promote cell proliferation, and accelerate bone healing of critical-size rat calvarial defects.

Efficacy and safety of a novel hemostatic material, BoneStat, compared with Ostene and Bone Wax in a rat calvarial defect model

2021 ◽  
pp. 039139882110214
Author(s):  
Seon Young Choi ◽  
Jiheon Rhim ◽  
Seon A Heo ◽  
Woo-Jung Han ◽  
Myung Hee Kim ◽  
...  
Keyword(s):  
Bone Healing ◽  
Water Solubility ◽  
Water Soluble ◽  
Calvarial Defect ◽  
Defect Model ◽  
Inflammatory Reactions ◽  
Alkylene Oxide ◽  
Rat Calvarial Defect ◽  
Inflammation Reaction ◽  
Consequent Increase

Hemostasis has critical significance during surgical procedures. Bone Wax has traditionally been commonly used for bone hemostasis despite well-documented undesirable side effects: hindering osteogenesis and induction of inflammatory reactions with consequent increase in infection rates. A later developed formulation, Ostene, offers an alternative to Bone Wax with lesser undesired effects. In this study, BoneStat, a newly developed bone hemostatic formulation comprising water-soluble alkylene oxide co-polymers, was evaluated for water solubility, hemostatic efficacy, ease of handling, bone healing efficacy, and inflammatory reactions compared with Bone Wax and Ostene in a rat calvarial defect model. More than 95% of BoneStat was dissolved in water within 48 h, as was Ostene, but not Bone Wax. The time to hemostasis using BoneStat was significantly faster than with Ostene or Bone Wax. BoneStat also improved ease of handling compared to Ostene or BoneWax. BoneStat- and Ostene-treated groups constantly showed better bone healing than with Bone Wax. The BoneStat and Ostene groups presented no evidence of chronic inflammation reaction contrary to Bone Wax. These results suggest improved hemostasis, ease of handling, non-hindering bone healing, and unnoticeable chronic inflammatory reactions with BoneStat. Thus, Bonestat is a useful and reliable formulation for mechanical hemostasis.

Melatonin decorated 3D-printed beta-tricalcium phosphate scaffolds promoting bone regeneration in a rat calvarial defect model

2019 ◽  
Vol 7 (20) ◽  
pp. 3250-3259 ◽  
Author(s):  
Yali Miao ◽  
Yunhua Chen ◽  
Xiao Liu ◽  
Jingjing Diao ◽  
Naru Zhao ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Calvarial Defect ◽  
Defect Model ◽  
Beta Tricalcium Phosphate ◽  
3D Printed ◽  
Rat Calvarial Defect

3D-printed β-TCP scaffolds decorated with melatonin via dopamine mussel-inspired chemistry enhance the osteogenesis and in vivo bone regeneration.

Calcification during bone healing in a standardised rat calvarial defect assessed by micro‐ CT and SEM ‐ EDX

Oral Diseases ◽  
2014 ◽  
Vol 21 (1) ◽  
pp. 74-82 ◽  
Author(s):  
H Okata ◽  
M Nakamura ◽  
A Henmi ◽  
S Yamaguchi ◽  
Y Mikami ◽  
...  
Keyword(s):  
Bone Healing ◽  
Calvarial Defect ◽  
Micro Ct ◽  
Rat Calvarial Defect
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