scholarly journals The process of magnesium ion modification of titanium surface and the sustained-release of magnesium ions from its surface

2020 ◽  
Vol 39 (3) ◽  
pp. 509-516
Author(s):  
Hanako SAKATSUME ◽  
Masatoshi TAKAHASHI ◽  
Mary Wambui KANYI ◽  
Yoshinaka SHIMIZU ◽  
Yukyo TAKADA
Keyword(s):  
Sustained Release ◽  
Titanium Surface ◽  
Magnesium Ion ◽  
Magnesium Ions ◽  
Modification Of Titanium

Initial MC3T3-E1 cell response on magnesium ion implanted titanium surface

Bone ◽  
2010 ◽  
Vol 47 ◽  
pp. S125
Author(s):  
H. Lee ◽  
L.-R. Cho ◽  
C.-J. Park ◽  
H. Shin
Keyword(s):  
Cell Response ◽  
Titanium Surface ◽  
Magnesium Ion ◽  
Ion Implanted

A Study on the Influence of Cysteine and Magnesium Ions on Brain Dementia

2014 ◽  
Vol 487 ◽  
pp. 161-164
Author(s):  
Lu Yin ◽  
Shuang Yue Zhu
Keyword(s):  
Vascular Dementia ◽  
Plasma Homocysteine ◽  
Diagnosis And Treatment ◽  
Magnesium Ion ◽  
Disease Development ◽  
Mechanism Analysis ◽  
Magnesium Ions ◽  
Patients Âgés ◽  
Dementia Patients ◽  
Relationship Of

As the population ages, dementia disease is increasingly becoming the most concerned social problems. According to the cause of dementia, it can be divided into many kinds class, among them with Alzheimer's Disease (Alzheimers diseases, AD) and Vascular Dementia (Vascular Dementia, VD) are common. Data shows it accounts for nearly 60% of total AD dementia patients, VD (20%), but only 2% of patients could get timely diagnosis and treatment, make its cognitive damage to a certain extent suppress and improve. for untimely diagnosis and treatment, most patients makes the disease development worse. In recent years, studies have shown that plasma Homocysteine,Hcy levels associated with AD. And studies show that from the power of the risk factors to the mechanism analysis, dementia disease level correlation with magnesium ions. On this basis, this study of plasma homocysteine in patients with AD,VD and magnesium ion detection results were analyzed retrospectively. Discuss their levels between the distributio relationship of patients ages in AD and VD.

scholarly journals A Novel Antibacterial Titanium Modification with a Sustained Release of Pac-525

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3306
Author(s):  
Yuzhu He ◽  
Yuanyuan Li ◽  
Enjun Zuo ◽  
Songling Chai ◽  
Xiang Ren ◽  
...  
Keyword(s):  
Sustained Release ◽  
Titanium Surface ◽  
Pure Titanium ◽  
Gram Negative Bacteria ◽  
Biomimetic Mineralization ◽  
Flat Rate ◽  
Bioactive Coating ◽  
Gram Positive Bacteria ◽  
Release Assay

For the benefit of antibacterial Ti on orthopedic and dental implants, a bioactive coating (Pac@PLGA MS/HA coated Ti) was deposited on the surface of pure titanium (Ti), which included two layers: an acid–alkali heat pretreated biomimetic mineralization layer and an electrosprayed Poly (D,L-lactide-co- glycolic acid) (PLGA) microsphere layer as a sustained-release system. Hydroxyapatite (HA) in mineralization layer was primarily prepared on the Ti followed by the antibacterial coating of Pac-525 loaded by PLGA microspheres. After observing the antimicrobial peptides distributed uniformly on the titanium surface, the release assay showed that the release of Pac-525 from Pac@PLGA MS/HA coated Ti provided a large initial burst followed by a slow release at a flat rate. Pac@PLGA MS/HA coated Ti exhibited a strong cytotoxicity to both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). In addition, Pac@PLGA MS/HA coated Ti did not affect the growth and adhesion of the osteoblast-like cell line, MC3T3-E1. These data suggested that a bionic mineralized composite coating with long-term antimicrobial activity was successfully prepared.

scholarly journals Activation of brain hexokinase by magnesium ions and by magnesium ion–adenosine triphosphate complex

1972 ◽  
Vol 130 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Daniel L. Purich ◽  
Herbert J. Fromm
Keyword(s):  
Simple Model ◽  
Complex Formation ◽  
Kinetic Data ◽  
Alternative Explanation ◽  
Metal Substrate ◽  
Magnesium Ion ◽  
Magnesium Ions ◽  
Substrate Complex ◽  
The Brain ◽  
Hill Plots

1. An alternative explanation for the kinetic data obtained by Bachelard (1971) for the brain hexokinase reaction is presented. 2. Apparently sigmoidal saturation curves for MgATP2− based upon Bachelard's (1971) studies can be corrected to hyperbolic curves by use of a stability constant for MgATP2− complex formation. 3. A number of other effects related to the concentration-dependent stability of the MgATP2− complex and to the presence of the inhibitory free uncomplexed ATP4− concentration are also explained in terms of a non-allosteric role for either Mg2+ or MgATP2− fully consistent with a number of previous reports on this enzyme. 4. A brief discussion of the validity of Hill plots in studies of multisubstrate co-operative enzymes is presented. 5. A simple model is presented that demonstrates how enzymes obeying Michaelis–Menten kinetics can demonstrate sigmoidal velocity responses if the true substrate of the reaction is the metal–substrate complex.

scholarly journals Improvement in Ti-porcelain bonding by SiO2 modification of titanium surface through cast method

2013 ◽  
Vol 32 (4) ◽  
pp. 564-571 ◽  
Author(s):  
Yanhua WEI ◽  
Zutai ZHANG ◽  
Ning DING ◽  
Dongxiang ZHENG ◽  
Hui LI ◽  
...  
Keyword(s):  
Titanium Surface ◽  
Modification Of Titanium

Surface Modification of Titanium by Hydrothermal Treatment

2007 ◽  
Vol 361-363 ◽  
pp. 609-612 ◽  
Author(s):  
Akiko Obata ◽  
Toshihiro Kasuga
Keyword(s):  
Mechanical Properties ◽  
Surface Modification ◽  
Hydrothermal Treatment ◽  
Alkaline Solution ◽  
Bone Substitute ◽  
Titanium Surface ◽  
Anatase Phase ◽  
Axis Orientation ◽  
Mouse Osteoblast ◽  
Modification Of Titanium

Titanium is well known as an implant material having excellent biocompatibility and mechanical properties for use in bone substitute. In the present study, to enhance the biocompatibility of titanium, its surface was modified by hydrothermal treatment using dilute alkaline solution. After hydrothermal treatment, anatase predominantly formed on a titanium surface. The anatase phase showed high crystallinity and c-axis orientation. The anatase layers with leaf-like and pyramid-like forms were observed on titanium autoclaved at 120 °C and 240 °C, respectively. The anatase formation and its morphology were significantly related to the autoclaving temperature. To estimate the cellular compatibility of the autoclaved titanium, mouse osteoblast-like cells (MC3T3-E1 cells) were cultured on the autoclaved titanium surface. After 7- days culturing, the number of the cells harvested from the autoclaved titanium was higher than that from untreated titanium. The surface modification of titanium by hydrothermal treatment involved the proliferation of the cells on its surface.

Sign in / Sign up

Export Citation Format

Share Document