scholarly journals Antibacterial efficacy of triple-layered poly(lactic-co-glycolic acid)/nanoapatite/lauric acid guided bone regeneration membrane on periodontal bacteria

2017 ◽  
Vol 36 (3) ◽  
pp. 260-265 ◽  
Author(s):  
Nur Najiha SAARANI ◽  
Kalitheerta JAMUNA-THEVI ◽  
Neelam SHAHAB ◽  
Hendra HERMAWAN ◽  
Syafiqah SAIDIN
Keyword(s):  
Bone Regeneration ◽  
Lauric Acid ◽  
Glycolic Acid ◽  
Guided Bone Regeneration ◽  
Antibacterial Efficacy ◽  
Periodontal Bacteria

Antibacterial Properties of Guided Bone Regeneration Membrane for Periodontal Applications

2014 ◽  
Vol 606 ◽  
pp. 47-50
Author(s):  
Nur Najiha Saarani ◽  
K. Jamuna-Thevi ◽  
Ida Idayu Muhammad ◽  
Hendra Hermawan
Keyword(s):  
Staphylococcus Aureus ◽  
Bone Regeneration ◽  
Composite Membrane ◽  
Lauric Acid ◽  
Antibacterial Properties ◽  
Guided Bone Regeneration ◽  
Significant Inhibition ◽  
Thermally Induced ◽  
Zones Of Inhibition ◽  
Gbr Membrane

Guided Bone Regeneration (GBR) membrane is used as a barrier to prevent soft tissue ingrowth and to encourage bone regeneration through cellular exclusion. This study aims to assess antibacterial properties of recently developed three-layered poly(lactic-co-glycolic acid) (PLGA) /lauric acid (LA) composite membrane towards Staphylococcus aureus. One of the outmost layers of three-layered membrane was incorporated with 1-3 wt% of LA. The composite membrane was developed using thermally induced phase separation/solvent leaching technique. SEM results shows formation of PLGA matrix with smaller pores by the addition of 1 wt% LA compared with pure PLGA membrane. Samples of 1.7 cm diameter disk containing 1, 2 and 3 wt% of lauric acid were tested and pure membrane without lauric acid was used as a control. Results showed that the zones of inhibition were 2.3 cm and 2.5 cm for the 2 wt% and 3 wt% LA-containing membranes, respectively. However, 1 wt% LA-containing membrane observed to have no inhibition at all, indicating that increasing concentration of LA has significant inhibition against Staphylococcus aureus. The 3 wt% LA composition will be used in the mechanically optimized membranes for degradation studies in future works.

Influence of calcium phosphates incorporation into poly(lactic-co-glycolic acid) electrospun membranes for guided bone regeneration

2020 ◽  
Vol 179 ◽  
pp. 109253
Author(s):  
Vivian Inês dos Santos ◽  
Claudia Merlini ◽  
Águedo Aragones ◽  
Karina Cesca ◽  
Márcio Celso Fredel
Keyword(s):  
Bone Regeneration ◽  
Glycolic Acid ◽  
Calcium Phosphates ◽  
Guided Bone Regeneration ◽  
Electrospun Membranes

scholarly journals Examination of Optimal Concentrations of Poly (Lactic-co-glycolic Acid) in Hexafluoroisopropyl Alcohol for Guided Bone Regeneration Membrane Prepared by Electrospinning

2020 ◽  
Vol 18 (3-4) ◽  
pp. 239-247
Author(s):  
Daisuke Isaji ◽  
Takehiro Watanabe ◽  
Takahiro Takahashi ◽  
Hiroki Sato ◽  
Hiroshi Nakada ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Glycolic Acid ◽  
Guided Bone Regeneration

Guided bone regeneration by poly(lactic-co-glycolic acid) grafted hyaluronic acid bi-layer films for periodontal barrier applications

2009 ◽  
Vol 5 (9) ◽  
pp. 3394-3403 ◽  
Author(s):  
Jung Kyu Park ◽  
Junseok Yeom ◽  
Eun Ju Oh ◽  
Mallikarjuna Reddy ◽  
Jong Young Kim ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Bone Regeneration ◽  
Glycolic Acid ◽  
Guided Bone Regeneration

scholarly journals Bilayer Poly(Lactic-co-glycolic acid)/Nano-Hydroxyapatite Membrane with Barrier Function and Osteogenesis Promotion for Guided Bone Regeneration

Materials ◽  
2017 ◽  
Vol 10 (3) ◽  
pp. 257 ◽  
Author(s):  
Li Fu ◽  
Zhanfeng Wang ◽  
Shujun Dong ◽  
Yan Cai ◽  
Yuxin Ni ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Barrier Function ◽  
Glycolic Acid ◽  
Guided Bone Regeneration

Importance of Poly(lactic-co-glycolic acid) in Scaffolds for Guided Bone Regeneration: A Focused Review

2015 ◽  
Vol 41 (4) ◽  
pp. e152-e157 ◽  
Author(s):  
Gabriel Castillo-Dalí ◽  
Rocío Velázquez-Cayón ◽  
M. Angeles Serrera-Figallo ◽  
Agustín Rodríguez-González-Elipe ◽  
José-Luis Gutierrez-Pérez ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Regeneration ◽  
Bone Tissue ◽  
Bone Repair ◽  
Glycolic Acid ◽  
Guided Bone Regeneration ◽  
Future Research ◽  
Loss Of Function ◽  
Important Health

Total or partial tissue damage and loss of function in an organ are two of the most serious and costly issues in human health. Initially, these problems were approached through organ and allogenic tissue transplantation, but this option is limited by the scarce availability of donors. In this manner, new bone for restoring or replacing lost and damaged bone tissue is an important health and socioeconomic necessity. Tissue engineering has been used as a strategy during the 21st century for mitigating this need through the development of guided bone regeneration scaffold and composites. In this manner, compared with other traditional methods, bone tissue engineering offers a new and interesting approach to bone repair. The poly-α-hydroxy acids, which include the copolymers of lactic acid and glycolic acid, have been used commonly in the fabrication of these scaffolds. The objective of our article was to review the characteristics and functions of scaffold with biomedical applications, with special interest in scaffold construction using poly(lactic-co-glycolic acid) polymers, in order to update the current methods used for fabrication and to improve the quality of these scaffolds, integrating this information into the context of advancements made in tissue engineering based on these structures. In the future, research into bone regeneration should be oriented toward a fruitful exchange between disciplines involved in tissue engineering, which is coming very close to filling the gaps in our ability to provide implants and restoration of functionality in bone tissue. Overcoming this challenge will provide benefits to a major portion of the population and facilitate substantial improvements to quality of life.

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