scholarly journals Use of a gelatin hydrogel membrane containing β-tricalcium phosphate for guided bone regeneration enhances rapid bone formation

2014 ◽  
Vol 33 (5) ◽  
pp. 674-680 ◽  
Author(s):  
Kanako NORITAKE ◽  
Shinji KURODA ◽  
Myat NYAN ◽  
Yuji ATSUZAWA ◽  
Motohiro UO ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Guided Bone Regeneration ◽  
Gelatin Hydrogel ◽  
Hydrogel Membrane

scholarly journals Digital Customized Titanium Mesh for Bone Regeneration of Vertical, Horizontal and Combined Defects: A Case Series

Medicina ◽  
2021 ◽  
Vol 57 (1) ◽  
pp. 60
Author(s):  
Daniele De Santis ◽  
Federico Gelpi ◽  
Giuseppe Verlato ◽  
Umberto Luciano ◽  
Lorena Torroni ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Regeneration ◽  
Case Series ◽  
Guided Bone Regeneration ◽  
Point Of View ◽  
Significant Gain ◽  
Titanium Mesh ◽  
New Bone Formation ◽  
Correct Method ◽  
Combined Defects

Background and Objective: Guided bone regeneration allows new bone formation in anatomical sites showing defects preventing implant rehabilitation. Material and Methods: The present case series reported the outcomes of five patients treated with customized titanium meshes manufactured with a digital workflow for achieving bone regeneration at future implant sites. A significant gain in both width and thickness was achieved for all patients. Results: From a radiographic point of view (CBTC), satisfactory results were reached both in horizontal and vertical defects. An average horizontal gain of 3.6 ± 0.8 mm and a vertical gain of 5.2 ± 1.1 mm. Conclusions: The findings from this study suggest that customized titanium meshes represent a valid method to pursue guided bone regeneration in horizontal, vertical or combined defects. Particular attention must be paid by the surgeon in the packaging of the flap according to a correct method called the “poncho” technique in order to reduce the most frequent complication that is the exposure of the mesh even if a partial exposure of one mesh does not compromise the final outcome of both the reconstruction and the healing of the implants.

In vitro evaluation of bilayer membranes of PLGA/hydroxyapatite/β-tricalcium phosphate for guided bone regeneration

2020 ◽  
Vol 112 ◽  
pp. 110849 ◽  
Author(s):  
Vivian Inês dos Santos ◽  
Claudia Merlini ◽  
Águedo Aragones ◽  
Karina Cesca ◽  
Márcio Celso Fredel
Keyword(s):  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Guided Bone Regeneration ◽  
Bilayer Membranes ◽  
In Vitro Evaluation

Effect of Silicate Incorporation in Alpha-Tricalcium Phosphate on Behaviors of Osteoblast-Like Cells

2016 ◽  
Vol 720 ◽  
pp. 90-94
Author(s):  
Masanobu Kamitakahara ◽  
Takashi Shirato ◽  
Taishi Yokoi ◽  
Hideaki Matsubara ◽  
Yasuaki Shibata ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Proliferation And Differentiation ◽  
Porous Silicate

Silicate-containing alpha-tricalcium phosphate (α-TCP) ceramics are expected to be useful scaffolds for bone regeneration because α-TCP shows high biodegradability and silicate ions are expected to promote the bone formation. We previously revealed that the porous silicate-containing α-TCP granules provided earlier bone formation and showed lower biodegradability than the porous silicate-free α-TCP granules in vivo. In order to reveal the mechanism of the bone formation promoted by silicate incorporation, the proliferation and differentiation of osteoblast-like cells on the silicate-containing and silicate-free α-TCP ceramics were examined in vitro. The silicate incorporation in α-TCP promoted the differentiation of osteoblast-like cells, and it might be one of the factors to promote bone formation In Vivo.

A composite polymer/tricalcium phosphate membrane for guided bone regeneration in maxillofacial surgery

2001 ◽  
Vol 58 (5) ◽  
pp. 564-569 ◽  
Author(s):  
Anita A. Ignatius ◽  
Michael Ohnmacht ◽  
Lutz E. Claes ◽  
Joachim Kreidler ◽  
Frank Palm
Keyword(s):  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Maxillofacial Surgery ◽  
Guided Bone Regeneration ◽  
Composite Polymer

scholarly journals Fabrication and evaluation of poly(lactic acid), chitosan, and tricalcium phosphate biocomposites for guided bone regeneration

2018 ◽  
Vol 135 (39) ◽  
pp. 46692 ◽  
Author(s):  
Srikanthan Ramesh ◽  
Lisa Lungaro ◽  
Dimitrios Tsikritsis ◽  
Eric Weflen ◽  
Iris V. Rivero ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Guided Bone Regeneration ◽  
Poly Lactic Acid

scholarly journals Porcine Collagen–Bone Composite Induced Osteoblast Differentiation and Bone Regeneration In Vitro and In Vivo

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 93 ◽  
Author(s):  
Eisner Salamanca ◽  
Chia Chen Hsu ◽  
Wan Ling Yao ◽  
Cheuk Sing Choy ◽  
Yu Hwa Pan ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Regeneration ◽  
Osteoblast Differentiation ◽  
Critical Size ◽  
Guided Bone Regeneration ◽  
Autogenous Bone ◽  
Critical Size Defects ◽  
Bone Formation Markers

Due to autogenous bone limitations, some substitute bone grafts were developed. Collagenated porcine graft (CPG) is able to regenerate new bone, although the number of studies is insufficient, highlighting the need for future studies to better understand the biomaterial. In order to understand better CPG′s possible dental guided bone regeneration indications, the aim of this work was to determine CPG′s biological capacity to induce osteoblast differentiation in vitro and guided bone regeneration in vivo, whilst being compared with commercial hydroxyapatite and beta tricalcium phosphate (HA/β-TCP) and porcine graft alone. Cell cytotoxicity (WST-1), alkaline phosphatase activity (ALP), and real-time polymerase chain reaction (qPCR) were assessed in vitro. Critical size defects of New Zealand white rabbits were used for the in vivo part, with critical size defect closures and histological analyses. WST-1 and ALP indicated that CPG directly stimulated a greater proliferation and confluency of cells with osteoblastic differentiation in vitro. Gene sequencing indicated stable bone formation markers, decreased resorption makers, and bone remodeling coupling factors, making the transition from osteoclast to osteoblast expression at the end of seven days. CPG resulted in the highest new bone regeneration by osteoconduction in critical size defects of rabbit calvaria at eight weeks. Nonetheless, all biomaterials achieved nearly complete calvaria defect closure. CPG was found to be osteoconductive, like porcine graft and HA/β-TCP, but with higher new bone formation in critical size defects of rabbit calvaria at eight weeks. CPG can be used for different dental guided bone regeneration procedures; however, further studies are necessary.

Evaluation of a new tricalcium phosphate for guided bone regeneration: an experimental study in the beagle dog

Odontology ◽  
2018 ◽  
Vol 107 (2) ◽  
pp. 209-218 ◽  
Author(s):  
Mario Pérez-Sayáns ◽  
Alejandro I. Lorenzo-Pouso ◽  
Pablo Galindo-Moreno ◽  
Fernando Muñoz-Guzón ◽  
Antonio González-Cantalapiedra ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Guided Bone Regeneration ◽  
Beagle Dog
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