scholarly journals Reduction of oxidative stress and CRP levels in hemodialysis patients by hydrogen gas inhalation

2021 ◽  
Vol 54 (9) ◽  
pp. 433-439
Author(s):  
Shohei Sokawa ◽  
Asuka Matsuura ◽  
Yuki Suga ◽  
Yui Sokawa ◽  
Tamao Kojima ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Hemodialysis Patients ◽  
Hydrogen Gas ◽  
Gas Inhalation ◽  
Hydrogen Gas Inhalation

scholarly journals Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome

2020 ◽  
Vol 67 (2) ◽  
pp. 214-221 ◽  
Author(s):  
Tomoyoshi Tamura ◽  
Masaru Suzuki ◽  
Kei Hayashida ◽  
Yosuke Kobayashi ◽  
Joe Yoshizawa ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cardiac Arrest ◽  
Hydrogen Gas ◽  
Gas Inhalation ◽  
Post Cardiac Arrest Syndrome ◽  
Hydrogen Gas Inhalation

Hydrogen Gas Inhalation Alleviates Radiation-Induced Bone Marrow Damage in Cancer Patients

2019 ◽  
Author(s):  
Shin-ichi Hirano ◽  
Yukimasa Aoki ◽  
Ryosuke Kurokawa ◽  
Xiao-Kang Li ◽  
Naotsugu Ichimaru ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cancer Patients ◽  
Hydrogen Gas ◽  
Bone Marrow Damage ◽  
Radiation Induced ◽  
Gas Inhalation ◽  
Hydrogen Gas Inhalation

Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model

2019 ◽  
Vol 74 ◽  
pp. 105646 ◽  
Author(s):  
Peikai Huang ◽  
Shushan Wei ◽  
Weihua Huang ◽  
Penghui Wu ◽  
Shuyu Chen ◽  
...  
Keyword(s):  
Alveolar Macrophage ◽  
Hydrogen Gas ◽  
Asthma Model ◽  
Macrophage Phagocytosis ◽  
Gas Inhalation ◽  
Hydrogen Gas Inhalation

scholarly journals Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice

2018 ◽  
Vol 10 (6) ◽  
pp. 3232-3243 ◽  
Author(s):  
Wenju Lu ◽  
Defu Li ◽  
Jieying Hu ◽  
Huijun Mei ◽  
Jiaze Shu ◽  
...  
Keyword(s):  
Cigarette Smoke ◽  
Hydrogen Gas ◽  
Gas Inhalation ◽  
Hydrogen Gas Inhalation

Effects of Hydrogen Gas Inhalation on Endometriosis in Rats

2016 ◽  
Vol 24 (2) ◽  
pp. 324-331 ◽  
Author(s):  
Y. He ◽  
J. Z. Shi ◽  
R. J. Zhang ◽  
D. X. Zhai ◽  
D. Zhang ◽  
...  
Keyword(s):  
Hydrogen Gas ◽  
Gas Inhalation ◽  
Hydrogen Gas Inhalation

scholarly journals A Comparison of the Antioxidant Effects Between Hydrogen Gas Inhalation and Vitamin C Supplementation in Response to a 60-Min Treadmill Exercise in Rat Gastrocnemius Muscle

2021 ◽  
Vol 12 ◽  
Author(s):  
Li Chaoqun ◽  
Zhao Yuqi ◽  
Zhou Shi ◽  
Yu Zhenghui ◽  
Wen Li
Keyword(s):  
Vitamin C ◽  
Signaling Pathways ◽  
Mitochondrial Biogenesis ◽  
Treadmill Exercise ◽  
Hydrogen Gas ◽  
Complex Iv ◽  
Vitamin C Supplementation ◽  
Gas Inhalation ◽  
Antioxidant Effects ◽  
Hydrogen Gas Inhalation

The reactive oxygen species (ROS) produced during exercise act as a double-edged sword because they may cause oxidative damage but also play a role in the signaling pathways. A supplementation of exogenous antioxidants can reduce the total amount of ROS during exercise while it may also affect the ROS’ role in the signaling pathways of mitochondrial biogenesis. It has been suggested that hydrogen gas, as an antioxidant, can selectively scavenge hydroxyl radicals but does not affect superoxide anion’s signal transduction. The aim of this study was to compare the effects of 1-h hydrogen gas inhalation 30min prior to a treadmill exercise on the key biomarkers of mitochondrial biogenesis and related signaling pathways, and the activities of endogenous antioxidant enzymes, with those of vitamin C, in the rat skeletal muscle. Eighty-one 8-week-old male Sprague–Dawley (SD) rats were randomly assigned to three interventions (exercise-only, exercise+4%H2, and exercise+vitamin C at 500mg/kg weight, with 27 rats under each intervention), and sampled at pre-, immediately post and 4h post a 60-min treadmill exercise at speed of 27m/min and flat inclination, with nine rats in each sub-group. Expression of mitochondrial biogenetic markers and related signaling molecules in gastrocnemius muscle, and concentrations of oxidative stress markers in serum were measured. Two-way ANOVA or Kruskal–Wallis analyses showed that both hydrogen inhalation and vitamin C supplementation significantly reduced serum levels of MDA immediately after exercise and AGEs 4h after exercise. The pre-exercise supplement of vitamin C significantly reduced mitochondrial complex IV concentrations and PGC-1α, NRF-1, TFAM gene expression levels compared to the pre-exercise group, but the hydrogen gas intervention did not result in a reduction in these measurements. Unlike vitamin C, hydrogen inhalation did not blunt post-exercise mitochondrial biogenetic signals, but resulted in an increase in complex IV concentration, activation of PGC-1α, and TFAM and NRF-2 gene transcription, and up-regulation of PGC-1α protein expression. The findings indicated that hydrogen gas inhalation could play the role as an effective antioxidant in response to the exercise, whilst it did not significantly affect mitochondrial biogenesis. The dose–response relationship and antioxidant effects in different types of exercise for hydrogen inhalation require further investigation.

1.2% Hydrogen gas inhalation protects the endothelial glycocalyx during hemorrhagic shock: a prospective laboratory study in rats

2020 ◽  
Vol 34 (2) ◽  
pp. 268-275
Author(s):  
Tsunehisa Sato ◽  
Soichiro Mimuro ◽  
Takasumi Katoh ◽  
Tadayoshi Kurita ◽  
Sang Kien Truong ◽  
...  
Keyword(s):  
Hemorrhagic Shock ◽  
Laboratory Study ◽  
Hydrogen Gas ◽  
Endothelial Glycocalyx ◽  
Gas Inhalation ◽  
Hydrogen Gas Inhalation
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