scholarly journals Deep white matter lesions and silent ischemic stroke detected by magnetic resonance imaging in community dwelling elderly subjects

Nosotchu ◽  
2002 ◽  
Vol 24 (3) ◽  
pp. 335-339
Author(s):  
Hiroshi Yao ◽  
Takefumi Yuzuriha
Keyword(s):  
Magnetic Resonance Imaging ◽  
Ischemic Stroke ◽  
White Matter ◽  
Magnetic Resonance ◽  
White Matter Lesions ◽  
Community Dwelling ◽  
Elderly Subjects ◽  
Resonance Imaging ◽  
Deep White Matter

A Magnetic Resonance Imaging Study of White Matter Lesions in Depression and Alzheimer's Disease

1996 ◽  
Vol 168 (4) ◽  
pp. 477-485 ◽  
Author(s):  
John O'brien ◽  
Patricia Desmond ◽  
David Ames ◽  
Isaac Schweitzer ◽  
Susan Harrigan ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
White Matter ◽  
Magnetic Resonance ◽  
Imaging Study ◽  
White Matter Lesions ◽  
Elderly Subjects ◽  
Resonance Imaging ◽  
Mri Scans

BackgroundWhite matter changes, as revealed by magnetic resonance imaging (MRI), may occur in depression and Alzheimer's disease.MethodT2-weighted MRI scans were performed in 39 control subjects, 61 subjects with NINCDS/ADRDA Alzheimer's disease and 60 subjects with DSM–III–R major depression. Deep white matter lesions (DWML) and periventricular lesions (PVL) were rated on a standard 0–3 scale by two radiologists blind to clinical diagnosis.ResultsAfter controlling for differences in vascular risk factors and current blood pressure, DWML were significantly more common in depressed subjects and PVL in Alzheimer's disease subjects compared to controls. DWML were most common in those presenting in late life with their first ever depression and 50% of such subjects had severe (grade 3) DWML.ConclusionAn association between DWML and depression and PVL and Alzheimer's disease is supported. The increase with DWML that occurs with ageing may predispose some elderly subjects to depression.

scholarly journals Magnetic resonance imaging abnormalities in young euthymic patients with bipolar affective disorder

2006 ◽  
Vol 189 (1) ◽  
pp. 81-82 ◽  
Author(s):  
Selim M. El-Badri ◽  
David A. Cousins ◽  
Sean Parker ◽  
Heather C. Ashton ◽  
Victor L. McAllister ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Bipolar Disorder ◽  
White Matter ◽  
Magnetic Resonance ◽  
Temporal Lobe ◽  
Bipolar Affective Disorder ◽  
White Matter Lesions ◽  
Resonance Imaging ◽  
Deep White Matter ◽  
Mri Scans

SummaryTemporal lobe and limbic structures may be abnormal in bipolar disorder. T2-weighted magnetic resonance imaging (MRI) scans frequently show deep white matter lesions. MRI was performed on 50 young (19–39 years) euthymic patients with bipolar disorder and 26 controls. Mean temporal lobe volumes were reduced in patients (right, 9.42 cm3; left, 6.33 cm3) but this could not be ascribed to a specific structure. Deep white matter lesions were present in 5 patients but no controls raising questions of their aetiological significance.

A 10-year longitudinal study of deep white matter lesions on magnetic resonance imaging

2021 ◽  
Author(s):  
Aiko Tamura ◽  
Nagato Kuriyama ◽  
Kentaro Akazawa ◽  
Etsuko Ozaki ◽  
Isao Watanabe ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Longitudinal Study ◽  
White Matter ◽  
Magnetic Resonance ◽  
White Matter Lesions ◽  
Resonance Imaging ◽  
Deep White Matter

scholarly journals Combined Brain-Heart Magnetic Resonance Imaging in Autoimmune Rheumatic Disease Patients with Cardiac Symptoms: Hypothesis Generating Insights from a Cross-Sectional Study

2020 ◽  
Vol 9 (2) ◽  
pp. 447 ◽  
Author(s):  
George Markousis-Mavrogenis ◽  
Dimos D. Mitsikostas ◽  
Loukia Koutsogeorgopoulou ◽  
Theodoros Dimitroulas ◽  
Gikas Katsifis ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Logistic Regression ◽  
White Matter ◽  
Magnetic Resonance ◽  
Odds Ratio ◽  
White Matter Lesions ◽  
Brain Lesions ◽  
Resonance Imaging ◽  
Deep White Matter ◽  
Cardiac Symptoms

Background: Autoimmune rheumatic diseases (ARDs) may affect both the heart and the brain. However, little is known about the interaction between these organs in ARD patients. We asked whether brain lesions are more frequent in ARD patients with cardiac symptoms compared with non-ARD patients with cardiovascular disease (CVD). Methods: 57 ARD patients with mean age of 48 ± 13 years presenting with shortness of breath, chest pain, and/or palpitations, and 30 age-matched disease-controls with non-autoimmune CVD, were evaluated using combined brain–heart magnetic resonance imaging (MRI) in a 1.5T system. Results: 52 (91%) ARD patients and 16 (53%) controls had white matter hyperintensities (p < 0.001) in at least one brain area (subcortical/deep/periventricular white matter, basal ganglia, pons, brainstem, or mesial temporal lobe). Only the frequency and number of subcortical and deep white matter lesions were significantly greater in ARD patients (p < 0.001 and 0.014, respectively). ARD vs. control status was the only independent predictor of having any brain lesion. Specifically for deep white matter lesions, each increase in ECV independently predicted a higher number of lesions [odds ratio (95% confidence interval): 1.16 (1.01–1.33), p = 0.031] in ordered logistic regression. Penalized logistic regression selected only ARD vs. control status as the most important feature for predicting whether brain lesions were present on brain MRI (odds ratio: 5.46, marginal false discovery rate = 0.011). Conclusions: Subclinical brain involvement was highly prevalent in this cohort of ARD patients and was mostly independent of the severity of cardiac involvement. However, further research is required to determine the clinical relevance of these findings.

Magnetic resonance imaging cinecisternography in patients with white matter lesions

1992 ◽  
Vol 2 (4) ◽  
pp. 213-215
Author(s):  
Yasuo Fukuuchi ◽  
Takahiro Amano ◽  
Hayao Shiga ◽  
Makoto Ichijo ◽  
Yoshiaki Itoh ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
White Matter Lesions ◽  
Resonance Imaging
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