Total Synthesis of Decahydrobenzo[d]xanthene Sesquiterpenoids Aureol, Strongylin A, and Stachyflin: Development of a New Strategy for the Construction of a Common Tetracyclic Core Structure

Heterocycles ◽  
2013 ◽  
Vol 87 (11) ◽  
pp. 2199 ◽  
Author(s):  
Tadashi Katoh
Keyword(s):  
Total Synthesis ◽  
Core Structure ◽  
New Strategy ◽  
Tetracyclic Core

A New Strategy toward the Total Synthesis of Stachyflin, A Potent Anti-Influenza A Virus Agent:  Concise Route to the Tetracyclic Core Structure

2002 ◽  
Vol 4 (25) ◽  
pp. 4483-4486 ◽  
Author(s):  
Mari Nakatani ◽  
Masahiko Nakamura ◽  
Akiyuki Suzuki ◽  
Munenori Inoue ◽  
Tadashi Katoh
Keyword(s):  
Total Synthesis ◽  
Influenza A Virus ◽  
Influenza A ◽  
Core Structure ◽  
New Strategy ◽  
Tetracyclic Core

A New Strategy Toward the Total Synthesis of Stachyflin (I), a Potent Antiinfluenza A Virus Agent: Concise Route to the Tetracyclic Core Structure (II).

ChemInform ◽  
2003 ◽  
Vol 34 (17) ◽  
Author(s):  
Mari Nakatani ◽  
Masahiko Nakamura ◽  
Akiyuki Suzuki ◽  
Munenori Inoue ◽  
Tadashi Katoh
Keyword(s):  
Total Synthesis ◽  
Core Structure ◽  
New Strategy ◽  
Tetracyclic Core

Total synthesis study of rauvomines A and B: construction of the pentacyclic core structure

2020 ◽  
Vol 7 (13) ◽  
pp. 1685-1689
Author(s):  
Binglu Wu ◽  
Zhi-Jiang Jiang ◽  
Jianbo Tang ◽  
Zhanghua Gao ◽  
Hongze Liang ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Aldol Reaction ◽  
Core Structure ◽  
Mukaiyama Aldol Reaction ◽  
New Strategy ◽  
Mukaiyama Aldol ◽  
Pentacyclic Core

The fifth ring of rauvomines can be annulated via a Mukaiyama-Aldol reaction as a new strategy for sarpagine scaffold construction.

Asymmetric Total Synthesis of (+)-Minfiensine by an Asymmetric Cascade Cyclization Strategy

Synlett ◽  
2017 ◽  
Vol 28 (17) ◽  
pp. 2199-2204 ◽  
Author(s):  
Lei Jiao ◽  
Ze-Xin Zhang ◽  
Si-Cong Chen
Keyword(s):  
Total Synthesis ◽  
Common Core ◽  
Core Structure ◽  
Asymmetric Total Synthesis ◽  
Cascade Cyclization ◽  
New Strategy ◽  
Efficient Construction ◽  
Synthesis Routes

The Strychnos alkaloid minfiensine and a series of akuammiline alkaloids, such as vincorine, aspidophylline A, and picrinine, possess a common core skeleton, a 4a,9a-heterocycle-fused tetrahydrocarbazole. Efficient construction of this core structure in a highly enantioselective manner would facilitate the total synthesis of these alkaloids. In this article, we briefly summarize the established strategies for obtaining this core structure, together with the corresponding total-synthesis routes, and we describe our own effort on the development of a new strategy, the asymmetric cascade dearomative cyclization, for the efficient total synthesis of (+)-minfiensine.

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