Synthesis and the First Structure–Activity Relationship Study of Imidazole Alkaloid from Red Ascidian as Aldose Reductase Inhibitors

Ryota Saito; Kenta Morikawa; Sota Uno; Shoko Higashi; Masaru Goto

doi:10.3987/com-19-14128

Synthesis and the First Structure–Activity Relationship Study of Imidazole Alkaloid from Red Ascidian as Aldose Reductase Inhibitors

Heterocycles ◽

10.3987/com-19-14128 ◽

2019 ◽

Vol 98 (8) ◽

pp. 1130

Author(s):

Ryota Saito ◽

Kenta Morikawa ◽

Sota Uno ◽

Shoko Higashi ◽

Masaru Goto

Keyword(s):

Aldose Reductase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Study

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Structure-Activity Relationship Study Reveals Benzazepine Derivatives of Luteolin as New Aldose Reductase Inhibitors for Diabetic Cataract

Current Drug Discovery Technologies ◽

10.2174/1570163813666160701023100 ◽

2016 ◽

Vol 13 (3) ◽

pp. 152-163 ◽

Cited By ~ 2

Author(s):

Jomon Sebastian

Keyword(s):

Aldose Reductase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Diabetic Cataract ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Study ◽

Derivatives Of

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Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship

General Physiology and Biophysics ◽

10.4149/gpb_2011_04_342 ◽

2012 ◽

Vol 30 (04) ◽

pp. 342-349 ◽

Cited By ~ 3

Author(s):

Maria Juskova ◽

Magdalena Majekova ◽

Vassilis Demopoulos ◽

 Milan Stefek

Keyword(s):

Acetic Acid ◽

Aldose Reductase ◽

Indole Acetic Acid ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Activity Structure ◽

Derivatives Of

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Quantitative structure–activity relationship of spirosuccinimide type aldose reductase inhibitors diminishing sorbitol accumulation in vivo

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2005.12.019 ◽

2006 ◽

Vol 14 (9) ◽

pp. 3090-3097 ◽

Cited By ~ 6

Author(s):

Kwangseok Ko ◽

Hoshik Won ◽

Youngdo Won

Keyword(s):

Aldose Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Of

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Synthesis and Structure-Activity Relationship Studies of Quinoxaline Derivatives as Aldose Reductase Inhibitors

ChemMedChem ◽

10.1002/cmdc.201300324 ◽

2013 ◽

Vol 8 (12) ◽

pp. 1913-1917 ◽

Cited By ~ 16

Author(s):

Bobin Wu ◽

Yanchun Yang ◽

Xiangyu Qin ◽

Shuzhen Zhang ◽

Chaojun Jing ◽

...

Keyword(s):

Aldose Reductase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quinoxaline Derivatives

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Racemic Descriptors for Quantitative Structure Activity Relationship of Spirosuccinimide Type Aldose Reductase Inhibitors

Bulletin of the Korean Chemical Society ◽

10.5012/bkcs.2004.25.12.1874 ◽

2004 ◽

Vol 25 (12) ◽

pp. 1874-1876 ◽

Cited By ~ 3

Keyword(s):

Aldose Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Of

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Synthesis and structure–activity relationship studies of phenolic hydroxyl derivatives based on quinoxalinone as aldose reductase inhibitors with antioxidant activity

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2017.01.006 ◽

2017 ◽

Vol 27 (4) ◽

pp. 887-892 ◽

Cited By ~ 9

Author(s):

Xin Hao ◽

Zhongfei Han ◽

Yang Li ◽

Chenying Li ◽

Xing Wang ◽

...

Keyword(s):

Antioxidant Activity ◽

Aldose Reductase ◽

Structure Activity Relationship ◽

Phenolic Hydroxyl ◽

Activity Relationship ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity

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Artificial neural networks applied to the quantitative structure—activity relationship study of dihydropteridine reductase inhibitors

Chemometrics and Intelligent Laboratory Systems ◽

10.1016/0169-7439(93)80086-w ◽

1993 ◽

Vol 19 (1) ◽

pp. 101-109 ◽

Cited By ~ 20

Author(s):

Xin-Hua Song ◽

Ru-Qin Yu

Keyword(s):

Neural Networks ◽

Artificial Neural Networks ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Dihydropteridine Reductase ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Study

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Discovery and quantitative structure-activity relationship study of lepidopteran HMG-CoA reductase inhibitors as selective insecticides

Pest Management Science ◽

10.1002/ps.4561 ◽

2017 ◽

Vol 73 (9) ◽

pp. 1944-1952 ◽

Cited By ~ 6

Author(s):

Yang-yang Zang ◽

Yuan-mei Li ◽

Yue Yin ◽

Shan-shan Chen ◽

Zhen-peng Kai

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Hmg Coa Reductase Inhibitors ◽

Relationship Study ◽

Coa Reductase ◽

Selective Insecticides

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A quantitative structure-activity relationship study of 3-hydroxy-3methylglutaryl-coenzyme A reductase inhibitors.

Journal of Pharmacobio-Dynamics ◽

10.1248/bpb1978.11.591 ◽

1988 ◽

Vol 11 (9) ◽

pp. 591-599 ◽

Cited By ~ 1

Author(s):

Dolly AGGARWAL ◽

Ranendra N. SAHA ◽

Jitendra K. GUPTA ◽

Satya P. GUPTA

Keyword(s):

Coenzyme A ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Study ◽

Coenzyme A Reductase

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Quantitative Structure-Activity Relationship Study on Some Dihydropteridine Reductase Inhibitors

Journal of Enzyme Inhibition ◽

10.3109/14756368909088476 ◽

1989 ◽

Vol 2 (4) ◽

pp. 231-237

Author(s):

R. Babbar ◽

J. K. Gupta ◽

S. P. Gupta

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Dihydropteridine Reductase ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Study

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Synthesis and the First Structure–Activity Relationship Study of Imidazole Alkaloid from Red Ascidian as Aldose Reductase Inhibitors

Structure-Activity Relationship Study Reveals Benzazepine Derivatives of Luteolin as New Aldose Reductase Inhibitors for Diabetic Cataract

Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship

Quantitative structure–activity relationship of spirosuccinimide type aldose reductase inhibitors diminishing sorbitol accumulation in vivo

Synthesis and Structure-Activity Relationship Studies of Quinoxaline Derivatives as Aldose Reductase Inhibitors

Racemic Descriptors for Quantitative Structure Activity Relationship of Spirosuccinimide Type Aldose Reductase Inhibitors

Synthesis and structure–activity relationship studies of phenolic hydroxyl derivatives based on quinoxalinone as aldose reductase inhibitors with antioxidant activity

Artificial neural networks applied to the quantitative structure—activity relationship study of dihydropteridine reductase inhibitors

Discovery and quantitative structure-activity relationship study of lepidopteran HMG-CoA reductase inhibitors as selective insecticides

A quantitative structure-activity relationship study of 3-hydroxy-3methylglutaryl-coenzyme A reductase inhibitors.

Quantitative Structure-Activity Relationship Study on Some Dihydropteridine Reductase Inhibitors

Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship