Synthesis and Structure-Activity Relationship Studies of Quinoxaline Derivatives as Aldose Reductase Inhibitors

Bobin Wu; Yanchun Yang; Xiangyu Qin; Shuzhen Zhang; Chaojun Jing; Changjin Zhu; Bing Ma

doi:10.1002/cmdc.201300324

Synthesis and Structure-Activity Relationship Studies of Quinoxaline Derivatives as Aldose Reductase Inhibitors

ChemMedChem ◽

10.1002/cmdc.201300324 ◽

2013 ◽

Vol 8 (12) ◽

pp. 1913-1917 ◽

Cited By ~ 16

Author(s):

Bobin Wu ◽

Yanchun Yang ◽

Xiangyu Qin ◽

Shuzhen Zhang ◽

Chaojun Jing ◽

...

Keyword(s):

Aldose Reductase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quinoxaline Derivatives

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Synthesis and the First Structure–Activity Relationship Study of Imidazole Alkaloid from Red Ascidian as Aldose Reductase Inhibitors

Heterocycles ◽

10.3987/com-19-14128 ◽

2019 ◽

Vol 98 (8) ◽

pp. 1130

Author(s):

Ryota Saito ◽

Kenta Morikawa ◽

Sota Uno ◽

Shoko Higashi ◽

Masaru Goto

Keyword(s):

Aldose Reductase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Study

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Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship

General Physiology and Biophysics ◽

10.4149/gpb_2011_04_342 ◽

2012 ◽

Vol 30 (04) ◽

pp. 342-349 ◽

Cited By ~ 3

Author(s):

Maria Juskova ◽

Magdalena Majekova ◽

Vassilis Demopoulos ◽

 Milan Stefek

Keyword(s):

Acetic Acid ◽

Aldose Reductase ◽

Indole Acetic Acid ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Activity Structure ◽

Derivatives Of

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Quantitative structure–activity relationship of spirosuccinimide type aldose reductase inhibitors diminishing sorbitol accumulation in vivo

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2005.12.019 ◽

2006 ◽

Vol 14 (9) ◽

pp. 3090-3097 ◽

Cited By ~ 6

Author(s):

Kwangseok Ko ◽

Hoshik Won ◽

Youngdo Won

Keyword(s):

Aldose Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Of

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Structure-Activity Relationship Study Reveals Benzazepine Derivatives of Luteolin as New Aldose Reductase Inhibitors for Diabetic Cataract

Current Drug Discovery Technologies ◽

10.2174/1570163813666160701023100 ◽

2016 ◽

Vol 13 (3) ◽

pp. 152-163 ◽

Cited By ~ 2

Author(s):

Jomon Sebastian

Keyword(s):

Aldose Reductase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Diabetic Cataract ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Study ◽

Derivatives Of

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Racemic Descriptors for Quantitative Structure Activity Relationship of Spirosuccinimide Type Aldose Reductase Inhibitors

Bulletin of the Korean Chemical Society ◽

10.5012/bkcs.2004.25.12.1874 ◽

2004 ◽

Vol 25 (12) ◽

pp. 1874-1876 ◽

Cited By ~ 3

Keyword(s):

Aldose Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Of

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Synthesis and structure–activity relationship studies of phenolic hydroxyl derivatives based on quinoxalinone as aldose reductase inhibitors with antioxidant activity

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2017.01.006 ◽

2017 ◽

Vol 27 (4) ◽

pp. 887-892 ◽

Cited By ~ 9

Author(s):

Xin Hao ◽

Zhongfei Han ◽

Yang Li ◽

Chenying Li ◽

Xing Wang ◽

...

Keyword(s):

Antioxidant Activity ◽

Aldose Reductase ◽

Structure Activity Relationship ◽

Phenolic Hydroxyl ◽

Activity Relationship ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity

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Structure–activity relationships studies of quinoxalinone derivatives as aldose reductase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.04.047 ◽

2014 ◽

Vol 80 ◽

pp. 383-392 ◽

Cited By ~ 49

Author(s):

Saghir Hussain ◽

Shagufta Parveen ◽

Xin Hao ◽

Shuzhen Zhang ◽

Wei Wang ◽

...

Keyword(s):

Aldose Reductase ◽

Structure Activity Relationships ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quinoxalinone Derivatives

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Design, synthesis and structure–activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2013.07.049 ◽

2013 ◽

Vol 69 ◽

pp. 115-124 ◽

Cited By ~ 21

Author(s):

Shadia A. Galal ◽

Ahmed S. Abdelsamie ◽

Salwa M. Soliman ◽

Jeremie Mortier ◽

Gerhard Wolber ◽

...

Keyword(s):

Tyrosine Kinase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Tyrosine Kinase Receptor ◽

Design Synthesis ◽

Chemopreventive Agent ◽

Structure Activity ◽

Quinoxaline Derivatives ◽

Relationship Of

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Perturbing pro-survival proteins using quinoxaline derivatives: A structure–activity relationship study

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2012.02.022 ◽

2012 ◽

Vol 20 (7) ◽

pp. 2227-2234 ◽

Cited By ~ 29

Author(s):

Rajkumar Rajule ◽

Vashti C. Bryant ◽

Hernando Lopez ◽

Xu Luo ◽

Amarnath Natarajan

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Quinoxaline Derivatives ◽

Relationship Study ◽

Survival Proteins

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Synergetic Effect and Structure−Activity Relationship of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors from Crataegus pinnatifida Bge.

Journal of Agricultural and Food Chemistry ◽

10.1021/jf903337f ◽

2010 ◽

Vol 58 (5) ◽

pp. 3132-3138 ◽

Cited By ~ 18

Author(s):

Xiao-Li Ye ◽

Wen-wen Huang ◽

Zhu Chen ◽

Xue-Gang Li ◽

Ping Li ◽

...

Keyword(s):

Coenzyme A ◽

Synergetic Effect ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Reductase Inhibitors ◽

Crataegus Pinnatifida ◽

Structure Activity ◽

Relationship Of ◽

Coenzyme A Reductase

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Synthesis and Structure-Activity Relationship Studies of Quinoxaline Derivatives as Aldose Reductase Inhibitors

Synthesis and the First Structure–Activity Relationship Study of Imidazole Alkaloid from Red Ascidian as Aldose Reductase Inhibitors

Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship

Quantitative structure–activity relationship of spirosuccinimide type aldose reductase inhibitors diminishing sorbitol accumulation in vivo

Structure-Activity Relationship Study Reveals Benzazepine Derivatives of Luteolin as New Aldose Reductase Inhibitors for Diabetic Cataract

Racemic Descriptors for Quantitative Structure Activity Relationship of Spirosuccinimide Type Aldose Reductase Inhibitors

Synthesis and structure–activity relationship studies of phenolic hydroxyl derivatives based on quinoxalinone as aldose reductase inhibitors with antioxidant activity

Structure–activity relationships studies of quinoxalinone derivatives as aldose reductase inhibitors

Design, synthesis and structure–activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor

Perturbing pro-survival proteins using quinoxaline derivatives: A structure–activity relationship study

Synergetic Effect and Structure−Activity Relationship of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors from Crataegus pinnatifida Bge.

Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship