scholarly journals Global dynamics of a vaccination model for infectious diseases with asymptomatic carriers

2016 ◽  
Vol 13 (4) ◽  
pp. 813-840 ◽  
Author(s):  
Martin Luther Mann Manyombe ◽  
Joseph Mbang ◽  
Jean Lubuma ◽  
Berge Tsanou
2018 ◽  
Vol 2018 ◽  
pp. 1-21 ◽  
Author(s):  
Rodrigue Yves M’pika Massoukou ◽  
Suares Clovis Oukouomi Noutchie ◽  
Richard Guiem

Vaccine-induced protection is substantial to control, prevent, and reduce the spread of infectious diseases and to get rid of infectious diseases. In this paper, we propose an SVEIR epidemic model with age-dependent vaccination, latency, and infection. The model also considers that the waning vaccine-induced immunity depends on vaccination age and the vaccinated individuals fall back to the susceptible class after losing immunity. The model is a coupled system of (hyperbolic) partial differential equations with ordinary differential equations. The global dynamics of the model is established through construction of appropriate Lyapunov functionals and application of Lasalle’s invariance principle. As a result, the global stability of the infection-free equilibrium and endemic equilibrium is obtained and is fully determined by the basic reproduction number R0.


2012 ◽  
Vol 72 (1) ◽  
pp. 261-279 ◽  
Author(s):  
Hongbin Guo ◽  
Michael Y. Li ◽  
Zhisheng Shuai

Author(s):  
Nelson Aguirre-Duarte

AbstractAsymptomatic but infectious people have been reported in many infectious diseases. Asymptomatic and pre-symptomatic carriers would be a hidden reservoir of COVID-19.AimThis review identifies primary empirical evidence about the ability of asymptomatic carriers to infect others with COVID-19 pandemic and reflects on the implications for control measures.MethodsA systematic review is followed by a narrative report and commentary inclusion criteria were: studies reporting primary data on asymptomatic or pre-symptomatic patients, who were considered to have passed on COVID-19 infection; and published in indexed journals or in peer review between January 1 and March 31, 2020.ResultsNine articles reported on 83 asymptomatic or pre-symptomatic persons.ConclusionsThe evidence confirms COVID-19 transmission from people who were asymptomatic at the time. A series of implications for health service response are laid out.


Author(s):  
Juan Zhou ◽  
Yingzheng Tan ◽  
Llingli Hu ◽  
Dan Li ◽  
Xiaojin He ◽  
...  

Abstract In view of the influence of ABO blood group antigens on infectious diseases, we explore the effect of ABO blood types on SARS-COV-2 infection. In this report, demographic data of 80 COVID-19 patients and 26 SARS-COV-2 asymptomatic carriers were collected based on electronic medical records. The results indicated that the distribution of ABO blood group in the confirmed patients was significantly different from asymptomatic carriers; importantly, antigen A carrier have significantly higher risk of developing into severe or critically cases than other types. These data present further evidence for the association of the blood groups to susceptibility to SARS-COV-2 infection.


2020 ◽  
pp. paper48-1-paper48-12
Author(s):  
Eugene Eremchenko ◽  
Vladimir Tikunov ◽  
Sergey Vylegzhanin ◽  
Alexander Fetishev

The article is a brief overview of the results of the current stage of study of the dynamics of infectious processes in the modern urban environment in Protvino (Russia) with the help of 3D-model of the town, made in the paradigm of the Digital Earth. Data for the period 2011-2016 (38791 events) were used. Spatial and temporal resolution “building-day” was achieved. It is demonstrated that infectious diseases rates even in neighboring buildings can vary significantly from one to another. The presence of buildings with both significantly higher and significantly lower rates of infectious diseases is shown. Such significant discrepancies between rates are difficult to explain by local ecological factors like air and water pollutions because of the generalized nature of their impact on such a small area. The example of the global dynamics of COVID-19 demonstrates the need to study both specific and non-specific factors for the local epidemic process. Prospectives of the future researches are discussed briefly.


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