scholarly journals Studies on the Time of Detection of Newcastle Disease Virus in the Brain in Relation to Other Organs

2010 ◽  
Vol 9 (5) ◽  
pp. 946-948 ◽  
Author(s):  
E.C. Okwor ◽  
J.O.A. Okoye ◽  
D.C. Eze
1966 ◽  
Vol 10 (1) ◽  
pp. 122
Author(s):  
S. Vadlamudi ◽  
R. P. Hanson

Pathogens ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 539
Author(s):  
Congriev Kumar Kabiraj ◽  
Tanjin Tamanna Mumu ◽  
Emdadul Haque Chowdhury ◽  
Mohammad Rafiqul Islam ◽  
Mohammed Nooruzzaman

The sequential pathology of a genotype XIII Bangladeshi strain of Newcastle disease virus (NDV) was studied in 5-weeks old chickens. Layer chickens of ISA Brown breed were inoculated through the intranasal and intraocular routes with the BD-C161/2010 strain of NDV and examined at different times post-infection (pi). NDV-infected chickens showed depression at 3 days pi (dpi) followed by dropped wings, paralysis and death starting at 4 dpi. Lungs of infected chickens showed hemorrhagic lesions starting at 24 hours pi (hpi) that was followed by pallor and slight contraction by 2 to 3 dpi and subsequently developed into severe hemorrhagic pneumonia with mononuclear cell infiltration. Hemorrhagic and necrotizing lesions were found in different visceral organs including proventriculus, intestine, gut-associated lymphoid tissues, liver and kidneys starting at 3 dpi that progressed rapidly. Severe lymphoid depletion was observed in the thymus, spleen and bursa of Fabricius starting at 1–3 dpi followed by hemorrhages, necrosis, inflammation and atrophy at 4–5 dpi. In the brain, mild neuronal lesions such as focal to diffuse encephalitis with encephalomalacia was observed at 2–3 dpi and moderate and diffuse meningoencephalitis with encephalomalacia at advanced stages. In conclusion, the BD-C161/2010 strain of NDV produced lesions typical of velogenic viscerotropic pathotype of NDV.


2016 ◽  
Vol 21 (1) ◽  
pp. 235-248
Author(s):  
Amani Saleh ◽  
Rola Ali ◽  
Mohamed Fawzy ◽  
Mokhtar Eltarabily

1978 ◽  
Vol 28 (1) ◽  
pp. 324-336 ◽  
Author(s):  
P L Collins ◽  
L E Hightower ◽  
L A Ball

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