The Beneficial Effects of Green Tea Extract and its Main Derivatives in Repairing Skin Burns of Rabbit

2011 ◽  
Vol 5 (2) ◽  
pp. 103-115 ◽  
Author(s):  
A.Y. Obaid ◽  
O.A. Abu-Zinada ◽  
H.K. Hussein
Keyword(s):  
Green Tea ◽  
Green Tea Extract ◽  
Beneficial Effects ◽  
Tea Extract

scholarly journals Beneficial Effects of Fermented Green Tea Extract in a Rat Model of Non-alcoholic Steatohepatitis

2009 ◽  
Vol 44 (3) ◽  
pp. 239-246 ◽  
Author(s):  
Kazuo Nakamoto ◽  
Fusako Takayama ◽  
Mitsumasa Mankura ◽  
Yuki Hidaka ◽  
Toru Egashira ◽  
...  
Keyword(s):  
Green Tea ◽  
Rat Model ◽  
Green Tea Extract ◽  
Beneficial Effects ◽  
Alcoholic Steatohepatitis ◽  
Tea Extract

scholarly journals Beneficial Effects of Gosha-jinki-gan and Green Tea Extract in Rats With Chemical Cystitis

2013 ◽  
Vol 122 (4) ◽  
pp. 270-277
Author(s):  
Sweety Nasrin ◽  
Ayaka Osano ◽  
Yoshihiko Ito ◽  
Shizuo Yamada
Keyword(s):  
Green Tea ◽  
Green Tea Extract ◽  
Beneficial Effects ◽  
Tea Extract

scholarly journals Beneficial Effects of Green Tea Extract in Gentamicin-Induced Acute Renal Failure in Rats / Povoljni efekti ekstrakta zelenog čaja na akutnu bubrežnu insuficijenciju uzrokovanu gentamicinom kod pacova

2015 ◽  
Vol 32 (1) ◽  
pp. 51-58 ◽  
Author(s):  
Milica Veljković ◽  
Sonja Ilić ◽  
Nenad Stojiljković ◽  
Ljubinka Velicković ◽  
Dragana Pavlović ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Renal Failure ◽  
Acute Renal Failure ◽  
Green Tea ◽  
Plasma Lipid ◽  
Green Tea Extract ◽  
Beneficial Effects ◽  
Tea Extract ◽  
Inflammatory Infiltrates ◽  
Plasma Lipid Peroxidation

Summary The aim of this study was to investigate whether green tea extract has beneficial effect on gentamicin-induced acute renal failure. The investigation was conducted on thirty-two Wistar rats divided into four groups of 8 animals each. Control (C) group received normal saline. GT group received green tea extract orally, 300mg/kg. GM group received gentamicin intraperitoneally, 100mg/kg and GT+GM group received both gentamicin and green tea extract. Histological sections of kidney in GM group revealed necrosis of proximal tubules, vacuolization of cytoplasm and massive mononuclear inflammatory infiltrates in interstitium. Coadministration of green tea with gentamicin had renoprotective effect and showed only mild infiltrations, normal glomeruli and alleviated tubular degeneration. Analysis of biochemical parameters showed significantly higher urea and creatinine serum concentrations in GM group in comparison with C group and GT+GM group (p<0.001). Plasma lipid peroxidation biomarker MDA was significantly higher in GM group than those in C group (p<0.001), whereas the values for GT+GM group were significantly lower than MDA recorded for GM group (p<0.001). Beneficial effects of green tea on gentamicin-induced nephrotoxicity is explained through decrease of oxidative stress and lipid peroxidation.Our results indicate that green tea administration has nephroprotective effect on oxidative stress and acute renal failure caused by gentamicin.

Epigallocatechin-3-Gallate-Rich Green Tea Extract Ameliorates Fatty Liver and Weight Gain in Mice Fed a High Fat Diet by Activating the Sirtuin 1 and AMP Activating Protein Kinase Pathway

2018 ◽  
Vol 46 (03) ◽  
pp. 617-632 ◽  
Author(s):  
Ui-Jin Bae ◽  
John Park ◽  
Il Woon Park ◽  
Byung Min Chae ◽  
Mi-Ra Oh ◽  
...  
Keyword(s):  
Weight Gain ◽  
Protein Kinase ◽  
Green Tea ◽  
High Fat Diet ◽  
Epigallocatechin Gallate ◽  
Green Tea Extract ◽  
Sirtuin 1 ◽  
High Fat ◽  
Beneficial Effects ◽  
Tea Extract

The prevalence of metabolic diseases has risen globally in parallel with the obesity epidemic over the past few decades. Green tea has been reported to have metabolically beneficial effects on obesity; however, the mechanism by which green tea regulates lipid metabolism is not clearly understood. Male c57BL/6 mice were fed a normal chow diet, a high-fat diet (HFD), or an HFD supplemented with various doses of epigallocatechin gallate-rich green tea extract (GTE) for 12 weeks. GTE supplementation reduced body weight gain, prevented hepatic fat accumulation, decreased hypertriglyceridemia, and improved hyperglycemia and insulin resistance in HFD-fed mice. The underlying mechanisms of these beneficial effects of GTE might involve the upregulation of sirtuin 1 and AMP activated protein kinase (AMPK) and the downregulation of enzymes related to de novo lipogenesis. Consistent with the in vivo findings, GTE increased the expression and activity of sirtuin 1, enhanced the binding of sirtuin 1 to liver kinase B1 (LKB1) and subsequent deacetylation of LKB1, and reduced triglyceride accumulation in HepG2 cells. These results suggest the possible therapeutic potential of dietary epigallocatechin gallate-rich GTE supplementation for preventing the development and progression of hepatic steatosis and obesity.

scholarly journals Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans.

2013 ◽  
Vol 60 (3) ◽  
Author(s):  
Jarosław Walkowiak ◽  
Joanna Bajerska ◽  
Angelika Kargulewicz ◽  
Aleksandra Lisowska ◽  
Gwidon Siedlerski ◽  
...  
Keyword(s):  
Single Dose ◽  
Green Tea ◽  
Test Meal ◽  
Exocrine Pancreatic Function ◽  
Green Tea Extract ◽  
Lipid Digestion ◽  
Cumulative Percentage ◽  
Beneficial Effects ◽  
Tea Extract

Green tea is known worldwide for its high content of polyphenolic compounds and multifactorial beneficial effects on human health. The role of green tea as an inhibitor of lipid hydrolysis is widely discussed. The aim of the study was to assess the influence of green tea extract on lipid digestion and absorption. The study comprised 32 healthy volunteers aged 23 to 30 years with normal exocrine pancreatic function. In all subjects (13)C-labelled mixed triglyceride breath test was performed twice with and without green tea extract ingestion. Cumulative percentage dose recovery was considered to reflect digestion and absorption of lipids. Values are expressed as medians and 1st-3rd quartile distribution. In all subjects, cumulative percentage dose recovery values were normal in a placebo test (36.8% ). These results were significantly higher (p=0.021) than those obtained in green tea extract test (28.8% ). Results of six tests with GTE were abnormal. Single dose of green tea extract taken with a test meal decreases lipid digestion and absorption in humans.

scholarly journals Prophylactic Catechin-Rich Green Tea Extract Treatment Ameliorates Pathogenic Enterotoxic Escherichia coli-Induced Colitis

Pathogens ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1573
Author(s):  
Jeong-Won Kim ◽  
Chang-Yeop Kim ◽  
Jin-Hwa Kim ◽  
Ji-Soo Jeong ◽  
Je-Oh Lim ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Green Tea ◽  
Green Tea Extract ◽  
Intestinal Damage ◽  
Ki 67 ◽  
E Coli ◽  
Beneficial Effects ◽  
Tea Extract

In this study, we explored the potential beneficial effects of green tea extract (GTE) in a pathogenic Escherichia coli (F18:LT:STa:Stx2e)-induced colitis model. The GTE was standardized with catechin and epigallocatechin-3-gallate content using chromatography analysis. Ten consecutive days of GTE (500 and 1000 mg/kg) oral administration was followed by 3 days of a pathogenic E. coli challenge (1 × 109 CFU/mL). In vitro antibacterial analysis showed that GTE successfully inhibited the growth of pathogenic E. coli, demonstrating over a 3-fold reduction under time- and concentration-dependent conditions. The in vivo antibacterial effect of GTE was confirmed, with an inhibition rate of approximately 90% when compared to that of the E. coli alone group. GTE treatment improved pathogenic E. coli-induced intestinal injury with well-preserved epithelial linings and villi. In addition, the increased expression of annexin A1 in GTE-treated jejunum tissue was detected, which was accompanied by suppressed inflammation-related signal expression, including TNFA, COX-2, and iNOS. Moreover, proliferation-related signals such as PCNA, CD44, and Ki-67 were enhanced in the GTE group compared to those in the E. coli alone group. Taken together, these results indicate that GTE has an antibacterial activity against pathogenic E. coli and ameliorates pathogenic E. coli-induced intestinal damage by modulating inflammation and epithelial cell proliferation.

Green Tea Extract Exposure Pattern Differenzially Affects Acetaminophen-Induced Hepatotoxicity

Planta Medica ◽  
2011 ◽  
Vol 77 (05) ◽  
Author(s):  
A Ali ◽  
X Yang ◽  
Q Shi ◽  
J Greenhaw ◽  
WF Salminen
Keyword(s):  
Green Tea ◽  
Green Tea Extract ◽  
Exposure Pattern ◽  
Tea Extract
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