scholarly journals Protective Role of Neuronal PAS Domain Protein 3 NPAS3 Gene in the Survival of Human Brain Stem Cell

2018 ◽  
Vol 11 (2) ◽  
pp. 76-82
Author(s):  
Xinyu Hu ◽  
Deepak Kamnasaran ◽  
Hao Yang Wang
Keyword(s):  
Stem Cell ◽  
Human Brain ◽  
Brain Stem ◽  
Protective Role ◽  
Pas Domain ◽  
Domain Protein

scholarly journals Examining the Protective Role of ErbB2 Modulation in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

2014 ◽  
Vol 141 (2) ◽  
pp. 547-559 ◽  
Author(s):  
Sandy Eldridge ◽  
Liang Guo ◽  
Jodie Mussio ◽  
Mike Furniss ◽  
John Hamre ◽  
...  
Keyword(s):  
Stem Cell ◽  
Pluripotent Stem Cell ◽  
Induced Pluripotent Stem Cell ◽  
Protective Role ◽  
Induced Pluripotent

scholarly journals Regulatory role of local tissue signal Del-1 in cancer and inflammation: a review

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Meng Li ◽  
Di Zhong ◽  
Guozhong Li
Keyword(s):  
Multiple Sclerosis ◽  
Bone Marrow ◽  
Protective Role ◽  
Regulatory Role ◽  
Cancer Microenvironment ◽  
Local Tissue ◽  
Domain Protein ◽  
And Migration ◽  
Cancer And Inflammation

AbstractDevelopmental endothelial locus-1 (Del-1) is a secretory, multifunctional domain protein. It can bind to integrins and phosphatidylserine. As a local tissue signal, it plays a regulatory role in the cancer microenvironment and inflammation. Del-1 has destructive effects in most cancers and is associated with the progression and invasion of some cancers. In contrast, Del-1 also plays a protective role in inflammation. Del-1 regulates inflammation by regulating the generation of neutrophils in bone marrow, inhibiting the recruitment and migration of neutrophils and accelerating the clearance of neutrophils by macrophages. Del-1 and IL-17 are reciprocally regulated, and their balance maintains immune system homeostasis. Del-1 is expected to become a new therapeutic target for inflammatory disorders such as multiple sclerosis.

scholarly journals Protective Role of R-spondin1, an Intestinal Stem Cell Growth Factor, against Radiation-Induced Gastrointestinal Syndrome in Mice

PLoS ONE ◽  
2009 ◽  
Vol 4 (11) ◽  
pp. e8014 ◽  
Author(s):  
Payel Bhanja ◽  
Subhrajit Saha ◽  
Rafi Kabarriti ◽  
Laibin Liu ◽  
Namita Roy-Chowdhury ◽  
...  
Keyword(s):  
Stem Cell ◽  
Growth Factor ◽  
Cell Growth ◽  
Protective Role ◽  
Intestinal Stem Cell ◽  
Radiation Induced ◽  
Stem Cell Growth Factor
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