scholarly journals Myopia Control with Orthokeratology Contact Lenses in Spain (MCOS): Study Design and General Baseline Characteristics

2009 ◽  
Vol 2 (4) ◽  
pp. 215-222 ◽  
Author(s):  
Jacinto Santodomingo-Rubido ◽  
César Villa-Collar ◽  
Bernard Gilmartin ◽  
Ramón Gutiérrez-Ortega
Keyword(s):  
Study Design ◽  
Contact Lenses ◽  
Baseline Characteristics ◽  
Myopia Control

scholarly journals The Influence of Genetics in Myopia Control: A Pilot Study

2021 ◽  
Vol 10 (4) ◽  
pp. 808
Author(s):  
Cristina Alvarez-Peregrina ◽  
Miguel Ángel Sánchez-Tena ◽  
Clara Martinez-Perez ◽  
Catalina Santiago-Dorrego ◽  
Thomas Yvert ◽  
...  
Keyword(s):  
Pilot Study ◽  
Treatment Response ◽  
Axial Length ◽  
Contact Lenses ◽  
Control Method ◽  
Saliva Sample ◽  
Experimental Studies ◽  
Strong Linkage Disequilibrium ◽  
Student’S T ◽  
Myopia Control

Background: Many epidemiological and experimental studies have established that myopia is caused by a complex interaction between common genetic and environmental factors. The objective of this study was to describe and compare the allelic and genotypic frequencies of the rs524952 (GJD2), rs8000973 (ZIC2), rs1881492 (CHRNG), rs1656404 (PRSS56), rs235770 (BMP2), and rs7744813 (KCNQ5) SNPs (single-nucleotide polymorphism) between responder and nonresponder patients who had undergone a two-year treatment with lenses for myopia control. Method: Twenty-eight participants from the MiSight Assessment Study Spain (MASS), who had received treatment for myopia control for two years with MiSight contact lenses, were examined. The criteria for better/worse treatment response was the change in the axial length (< / ≥ 0.22 mm two years after the treatment). The clinical procedure consisted of the extraction of a saliva sample, and the participants also underwent an optometric examination. Genetic data were analyzed using SNPStats software (Catalan Institute of Oncology, Barcelona, Spain), and statistical analysis was performed using SPSS v.25 (SPSS Inc., Chicago, IL, USA). Demographic variables were analyzed using the Student’s t-test. Results: The T allele, the one with the lowest frequency, of the “rs235770” SNP was associated with a better treatment response [AL/CR (axial length/corneal radius): OR = 3.37; CI = 1.079–10.886; SE (spherical equivalent): OR = 1.26; CI: = 0.519–57.169; p = 0.019). By performing haplotype analysis, significant differences were found between the rs235770…rs1881492 and rs235770–rs1656404 polymorphisms. The latter presented a strong linkage disequilibrium with each other (r2 ≥ 0.54). Conclusion: The result of lens therapies for myopia control could vary depending on genetic variants. Studies with a larger sample are needed to confirm the results presented in this pilot study.

scholarly journals Myopia Control with Combination Low-Dose Atropine and Peripheral Defocus Soft Contact Lenses: A Case Series

2021 ◽  
pp. 548-554
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Yair Morad
Keyword(s):  
Low Dose ◽  
Contact Lenses ◽  
Case Series ◽  
Concentric Circle ◽  
Retrospective Case ◽  
Soft Contact ◽  
Myopia Progression ◽  
Soft Contact Lenses ◽  
Center Distance ◽  
Myopia Control

The goal of this retrospective case series is to demonstrate the effectivity of combination low-dose atropine therapy with peripheral defocus, double concentric circle design with a center distance soft contact lenses at controlling myopia progression over 1 year of treatment. Included in this series are 3 female children aged 8–10 years with progressing myopia averaging −4.37 ± 0.88 D at the beginning of treatment. Their average annual myopic progression during the 3 years prior to therapy was 1.12 ± 0.75 D. They had not attempted any myopia control treatments prior to this therapy. The children were treated with a combination of 0.01% atropine therapy with spherical peripheral defocus daily replacement soft lenses MiSight<sup>®</sup> 1 day (Cooper Vision, Phoenix, AZ, USA). They underwent cycloplegic refraction, and a slit-lamp evaluation every 6 months which confirmed no adverse reactions or staining was present. Each of the 3 children exhibited an average of 0.25 ± 0.25 D of myopia progression at the end of 1 year of treatment. To the best of the authors’ knowledge, this is the first published study exhibiting that combining low-dose atropine and peripheral defocus soft contact lenses is effective at controlling children’s moderate to severe myopia progression during 1 year of therapy.

The role of bifocal and contact lenses in myopia control

2009 ◽  
Vol 66 (S185) ◽  
pp. 162-166 ◽  
Author(s):  
T. Grosvenor ◽  
D. A. Goss
Keyword(s):  
Contact Lenses ◽  
Myopia Control

Results of a two-year clinical study of myopia control with bifocal defocus-inducing soft contact lenses

2021 ◽  
Vol 137 (3) ◽  
pp. 5
Author(s):  
S.E. Avetisov ◽  
A.V. Myagkov ◽  
A.V. Egorova ◽  
Z.N. Poskrebysheva ◽  
O.A. Zhabina
Keyword(s):  
Clinical Study ◽  
Contact Lenses ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Myopia Control

scholarly journals The Progression of the Stargardt Disease Type 4 (ProgStar-4) Study: Design and Baseline Characteristics (ProgStar-4 Report No. 1)

2018 ◽  
Vol 60 (3) ◽  
pp. 185-194 ◽  
Author(s):  
Rupert W. Strauss ◽  
Beatriz Muñoz ◽  
Mohamed I. Ahmed ◽  
Millena Bittencourt ◽  
Etienne M. Schönbach ◽  
...  
Keyword(s):  
Study Design ◽  
Disease Type ◽  
Stargardt Disease ◽  
Baseline Characteristics

The SURCOUF study: Design and baseline characteristics of a prospective population-based cohort on diabetes care in France

2019 ◽  
Vol 80 (2) ◽  
pp. 136-137
Author(s):  
Emeric Scharbarg ◽  
Matthieu Wargny ◽  
Brice Leclère ◽  
Patrick Plunian ◽  
Maja Velkovski-Rouyer ◽  
...  
Keyword(s):  
Study Design ◽  
Diabetes Care ◽  
Population Based ◽  
Baseline Characteristics
Sign in / Sign up

Export Citation Format

Share Document