Postprandial hormone response after endurance or resistance exercise in obese women

2017 ◽  
Vol 13 (4) ◽  
pp. 227-235
Author(s):  
P.M. Davitt ◽  
G.C. Henderson ◽  
A.J. Walker ◽  
S.M. Arent
Keyword(s):  
Area Under The Curve ◽  
Exercise Bout ◽  
Fat Free Mass ◽  
Hormonal Changes ◽  
Obese Women ◽  
Post Exercise ◽  
Postprandial Period ◽  
Single Bout ◽  
Main Effect ◽  
Total Body

Physiological changes with endurance exercise (EE) and resistance training (RT) are likely influenced by the metabolic and hormonal response to each exercise bout, but may be blunted in obese individuals. To compare acute effects of EE, RT, and a control upon hormonal changes in obese women, sedentary, obese women (n=12) participated in a randomised crossover-design study on 3 occasions. EE consisted of treadmill walking (65% VO2max for 1 h). A total-body RT workout consisted of 3 sets of 10 repetitions, 90 s rest for 8 exercises at 90-100% of 10RM. Blood samples were taken 30 min before exercise (0 min), 30 min post-exercise (120 min), and again at 200, 280, and 520 min to assess changes in growth hormone (GH), cortisol, and insulin throughout the postprandial period. A 20 kcal/kg fat-free mass (FFM) meal was given after post-exercise blood sample. There was a main effect of condition for GH ΔAUC (change in area under the curve), with both RT and EE significantly different from the control (RT = 463.0±138.2; EE = 243.2±131.6; Control = -90.4±157.6 ng/ml * 400 min, P<0.02, Control vs EE, effect size (ES) = 2.3; Control vs RT, ES=3.7; EE vs RT, ES=1.6). There were no condition effects for cortisol or insulin ΔAUC. There were no significant time-by-condition interactions for any variables. In obese women, circulating GH concentration is enhanced in the postprandial state following a single bout of either EE or RT, with the GH response being more robust than cortisol or insulin. As circulating GH has shown to be reduced in obesity, the present observations could be considered beneficial, particularly alongside the absence of enhanced cortisol level after exercise.

Effect of a single bout of exercise and chronic exercise training on insulin sensitivity in racing sled dogs

2014 ◽  
Vol 10 (3) ◽  
pp. 167-172 ◽  
Author(s):  
S.E. Pratt-Phillips ◽  
R.J. Geor ◽  
M. Buser ◽  
A. Zirkle ◽  
A. Moore ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Exercise Training ◽  
Exercise Bout ◽  
Post Exercise ◽  
Exercise Challenge ◽  
Sled Dogs ◽  
Significant Difference ◽  
Single Bout ◽  
Three Stages

Two experiments were designed to investigate the role of exercise on insulin sensitivity (IS) in Alaskan racing sled dogs. In both experiments, IS was quantified with an isoglycemic-hyperinsulinemic clamp (IHC), whereby IS was defined as the glucose infusion rate (GIR) divided by the mean insulin concentration during the clamp. In Experiment 1, IS was quantified in 12 racing sled dogs during three stages of exercise training: unexercised for 4 months over the summer (deconditioned), and after two and four months of exercise conditioning. At each stage IS was assessed in unexercised dogs (n=6) and 60 h following a standard exercise challenge (n=6) consisting of a 35.4 km run completed in 2.5 h. In Experiment 2, IS was assessed in deconditioned dogs (n=6) and in well-conditioned dogs that had either completed a 708 km race 5-days prior (n=3) or were unraced for the previous month (n=3). In Experiment 1, there were no significant differences (Pã0.05) in GIR or IS between the three levels of conditioning, nor were there any effects of the exercise bout 60 h prior to the IHC. In Experiment 2 there was no significant difference in IS between well-conditioned dogs and untrained dogs (Pã0.05). However, dogs that completed a 708 km race 5-days prior to the IHC had a significantly higher IS than dogs that were deconditioned and those that were conditioned but unraced. These results suggest that the workload of an exercise challenge is a factor in post-exercise changes in IS but that exercise conditioning has little impact on IS in Alaskan sled dogs.

scholarly journals Consistency in compensatory eating responses following acute exercise in inactive, overweight and obese women

2015 ◽  
Vol 113 (7) ◽  
pp. 1170-1177 ◽  
Author(s):  
Jessica L. Unick ◽  
Kevin C. O'Leary ◽  
Leah Dorfman ◽  
J. Graham Thomas ◽  
Kelley Strohacker ◽  
...  
Keyword(s):  
Acute Exercise ◽  
Intraclass Correlation ◽  
Exercise Bout ◽  
Moderate Intensity ◽  
Exercise Session ◽  
Obese Women ◽  
Post Exercise ◽  
Overweight Women ◽  
Increase Energy Intake ◽  
The Difference

It is often assumed that some individuals reliably increase energy intake (EI) post-exercise (‘compensators’) and some do not (‘non-compensators’), leading researchers to examine the characteristics that distinguish these two groups. However, it is unclear whether EI post-exercise is stable over time. The present study examined whether compensatory eating responses to a single exercise bout are consistent within individuals across three pairs of trials. Physically inactive, overweight/obese women (n28, BMI 30·3 (sd2·9) kg/m2) participated in three pairs of testing sessions, with each pair consisting of an exercise (30 min of moderate-intensity walking) and resting testing day. EI was measured using a buffet meal 1 h post-exercise/rest. For each pair, the difference in EI (EIdiff= EIex− EIrest) was calculated, where EIexis the EI of the exercise session and EIrestis the EI of the resting session, and women were classified as a ‘compensator’ (EIex>EIrest) or ‘non-compensator’ (EIex≤ EIrest). The average EI on exercise days (3328·0 (sd1686·2) kJ) was similar to those on resting days (3269·4 (sd1582·4) kJ) (P= 0·67). Although EI was reliable within individuals across the three resting days (intraclass correlation coefficient (ICC) 0·75, 95 % CI 0·60, 0·87;P< 0·001) and three exercise days (ICC 0·83, 95 % CI 0·70, 0·91;P< 0·001), the ICC for EIdiffacross the three pairs of trials was low (ICC 0·20, 95 % CI − 0·02, 0·45;P= 0·04), suggesting that compensatory eating post-exercise is not a stable construct. Moreover, the classification of ‘compensators’/‘non-compensators’ was not reliable (κ =− 0·048;P= 0·66). The results were unaltered when ‘relative’ EI was used, which considers the energy expenditure of the exercise/resting sessions. Acute compensatory EI following an exercise bout is not reliable in overweight women. Seeking to understand what distinguishes ‘compensators’ from ‘non-compensators’ based on a single eating episode post-exercise is not justified.

scholarly journals GH Responsiveness to Combined GH-Releasing Hormone and Arginine Administration in Obese Patients with Fibromyalgia Syndrome

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Antonello E. Rigamonti ◽  
Graziano Grugni ◽  
Marco Arreghini ◽  
Paolo Capodaglio ◽  
Alessandra De Col ◽  
...  
Keyword(s):  
Area Under The Curve ◽  
Tender Point ◽  
Fat Free Mass ◽  
Obese Women ◽  
Arginine Test ◽  
High Prevalence ◽  
Stimulation Tests ◽  
Severely Obese ◽  
Prevalence Of Obesity ◽  
Ghrh Plus Arginine Test

Reportedly, fibromyalgia (FM) is frequently associated with reduced IGF-1 levels and GH hyporesponsiveness to different GH stimulation tests. Since there is a high prevalence of obesity in FM, and obesity itself is characterized by hyposomatotropism, the aim of this study was to assess IGF-1 levels and GH responsiveness in sixteen severely obese women suffering from FM, who, subdivided into two subgroups on the basis of their age-dependent IGF-1 values (> or <−2 SDS), underwent the combined GHRH plus arginine test. Four out of 16 obese women with FM (25%) had low IGF-1 SDS values, 2 cases of this subgroup (12.5%) failing also to normally respond to the test. Among patients with normal GH responses, 4 showed a delayed GH peak. The subgroup with low IGF-1 SDS values had higher BMI than that with normal IGF-1 SDS. GH peak and area under the curve were not correlated with CRP, ESR, or tender point score, while significant correlations were found with fat-free mass and fat mass. In conclusion, this study shows the existence of a high prevalence of GH-IGF-1 dysfunction in patients with both FM and obesity, presumably as a consequence of the obese rather than fibromyalgic condition.

scholarly journals Exercise shifts hypothetical food choices towards greater amounts and more immediate consumption

2020 ◽  
Author(s):  
Karsten Koehler ◽  
Safiya E Beckford ◽  
Elise Thayer ◽  
Alexandra R Martin ◽  
Julie B Boron ◽  
...  
Keyword(s):  
Food Intake ◽  
Aerobic Exercise ◽  
Acute Exercise ◽  
Food Preferences ◽  
Exercise Bout ◽  
Food Choices ◽  
Post Exercise ◽  
Single Bout ◽  
Electronic Questionnaires ◽  
The Impact

Although exercise modulates appetite regulation and food intake, it remains poorly understood how exercise impacts decision making about food. The purpose of the present study was to assess the impact of an acute exercise bout on hypothetical choices related to the amount and timing of food intake. Forty-one healthy participants (22.0 ± 2.6 years; 23.7 ± 2.5 kg/m2, 56% female) completed 45 minutes of aerobic exercise and a resting control condition in randomized order. Food amount preferences and intertemporal food preferences (preference for immediate vs. delayed consumption) were assessed using electronic questionnaires with visual food. Compared to rest, exercise resulted in a greater increase in the food amount selected, both immediately post exercise (+25.8 ± 11.0 vs. +7.8 ± 11.0 kcal/item, p = 0.02) and 30 min post exercise (+47.3 ± 12.4 vs. +21.3 ± 12.4 kcal/item, p = 0.005). Exercise further resulted in a greater increase in the preference for immediate consumption immediately post exercise (+0.23 ± 0.10 vs. +0.06 ± 0.10; p = 0.03) and 30 min post exercise (+0.30 ± 0.12 vs. +0.08 ± 0.12; p = 0.01). Our findings demonstrate that a single bout of aerobic exercise shifts hypothetical food choices towards greater amounts and more immediate consumption, highlighting the importance of the timing of food choices made in the exercise context.

Influence of muscular development, obesity, and age on the fat-free mass of adults

1976 ◽  
Vol 41 (2) ◽  
pp. 223-229 ◽  
Author(s):  
J. Womersley ◽  
J. V. Durnin ◽  
K. Boddy ◽  
M. Mahaffy
Keyword(s):  
Body Fat ◽  
The Body ◽  
Fat Free Mass ◽  
Potassium Content ◽  
Whole Body ◽  
Obese Women ◽  
Men And Women ◽  
Muscular Development ◽  
Total Body ◽  
Water Measurement

Body fat and the fat-free mass (FFM) were estimated in 36 men and 43 women deliberately chosen to represent a variety of physical types; these were 1) young sedentary, 2) “muscular,” 3) younger obese, 4) older obese, and 5) older nonobese individuals of both sexes. The body fat and the FFM were estimated from measurements of body density (by total immersion in water, measurement being made of the residual volume of air present in the lungs at immersion) and from measurements of total body potassium (using a whole-body monitor to assess the natural 40K isotope present in the body). The muscular men and women and the younger obese men and women had a considerably greater FFM and thus had greater quantities of potassium than the corresponding sedentary groups. There were significantly different estimates of the FFM calculated from density and from total body K in three groups, the sedentary young men, the muscular, and the younger obese women. The density and the potassium content of the FFM appear to decline with obesity and aging. Muscular development is associated with a decrease in the density but an increase in the potassium content of the FFM.

Time-course of changes in cardiac function during recovery after acute exercise

2007 ◽  
Vol 32 (6) ◽  
pp. 1164-1169 ◽  
Author(s):  
Karen Y. Wonders ◽  
David S. Hydock ◽  
Reid Hayward
Keyword(s):  
Lipid Peroxidation ◽  
Cardiac Function ◽  
Time Course ◽  
Acute Exercise ◽  
Exercise Bout ◽  
Left Ventricular ◽  
Antioxidant Potential ◽  
Exhaustive Exercise ◽  
Post Exercise ◽  
Single Bout

Exercise-induced cardiac dysfunction (EICD) has been observed immediately following exhaustive exercise in trained individuals, but limited and conflicting data are available regarding EICD in a previously untrained population days after an exhaustive exercise bout. The purpose of this study was to examine the effects of a single bout of acute exercise on cardiac function during the 72 h after exercise and identify potential contributing mechanisms. After completing an acute exercise bout on a motorized treadmill (25 m/min, 5% grade, 60 min), rats were sacrificed immediately, 24 h, 48 h, or 72 h after the exercise bout. At the scheduled time of sacrifice, hearts were isolated and perfused for determination of ex vivo cardiac function, and examined for malondialdehyde (MDA), a lipid peroxidation index, and antioxidant potential (AOP). During the 48 h post exercise, left ventricular developed pressure decreased by 30%, dP/dtmax declined by 37%, and dP/dtmin showed a 34% decrease (p < 0.05). By 72 h, cardiac function had returned to control levels. MDA was increased immediately after the exercise bout and at the 24 and 48 h intervals (p < 0.05). Conversely, AOP progressively decreased at the 24 and 48 h intervals. As with cardiac function, MDA and AOP had returned to control levels by 72 h post-exercise. These data indicate that a single bout of prolonged, moderately intense exercise performed by previously sedentary rats impaired cardiac function for up to 48 h. This decrement in cardiac function was associated with increased lipid peroxidation and decreased antioxidant potential.

The Cortisol Response to Normal and Nocturnal Awakening

2000 ◽  
Vol 14 (1) ◽  
pp. 24-28 ◽  
Author(s):  
F. Hucklebridge ◽  
A. Clow ◽  
H. Rahman ◽  
P. Evans
Keyword(s):  
Area Under The Curve ◽  
Secretory Activity ◽  
Linear Increase ◽  
Cortisol Response ◽  
The Awakening ◽  
Basal Cortisol ◽  
Free Cortisol ◽  
Main Effect ◽  
Nocturnal Awakening ◽  
Night Awakening

Abstract Free cortisol as measured in saliva increases markedly following awakening. It is not clear, however, whether this is truly a stress-neuroendocrine response to awakening or a manifestation of the hypothalamic-pituitary-adrenal (HPA) circadian cycle. We investigated whether the awakening cortisol response can be generated in the middle of nocturnal sleep, when secretory activity in the HPA axis is low. In a within subject design, salivary cortisol response was measured under three different awakening conditions: (1) awakening at the normal morning awakening time; (2) awakening four hours prior to normal awakening time, and (3) awakening the following morning after interrupted sleep. The overall main effect was a linear increase in free cortisol following awakening with no significant interaction with awakening condition. Cortisol levels, as determined by area under the cortisol curve calculated with reference to zero, did differ by awakening condition. The two morning awakening conditions were comparable but values were lower for night awakening. Area under the curve change (calculated with reference to the first awakening cortisol base value), however, did not distinguish the three awakening conditions. We conclude from these data that there is a clear free cortisol response to awakening for both nocturnal and morning awakening although the absolute levels produced are lower for nocturnal awakening when basal cortisol is low. Nocturnal interruption of sleep did not affect the subsequent morning response.

Obesity does not Impair Ambulatory Cardiovascular and Autonomic Responses Post-exercise

2021 ◽  
Author(s):  
Gabriel Kolesny Tricot ◽  
Fabiula Isoton Isoton Novelli ◽  
Lucieli Teresa Cambri
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Diastolic Blood Pressure ◽  
Maximal Exercise ◽  
Young Men ◽  
Autonomic Modulation ◽  
Incremental Test ◽  
Post Exercise ◽  
Cardiac Autonomic Modulation ◽  
Main Effect

AbstractThis study aimed to assess whether obesity and/or maximal exercise can change 24 h cardiac autonomic modulation and blood pressure in young men. Thirty-nine men (n: 20; 21.9±1.8 kg·m−2, and n: 19; 32.9±2.4 kg·m−2) were randomly assigned to perform a control (non-exercise) and an experimental day exercise (after maximal incremental test). Cardiac autonomic modulation was evaluated through frequency domain heart rate variability (HRV). Obesity did not impair the ambulatory HRV (p>0.05), however higher diastolic blood pressure during asleep time (p=0.02; group main effect) was observed. The 24 h and awake heart rate was higher on the experimental day (p<0.05; day main effect), regardless of obesity. Hypotension on the experimental day, compared to control day, was observed (p<0.05). Obesity indicators were significantly correlated with heart rate during asleep time (Rho=0.34 to 0.36) and with ambulatory blood pressure(r/Rho=0.32 to 0.53). Furthermore, the HRV threshold workload was significantly correlated with ambulatory heart rate (r/Rho=− 0.38 to−0.52). Finally, ambulatory HRV in obese young men was preserved; however, diastolic blood pressure was increased during asleep time. Maximal exercise caused heart rate increase and 24h hypotension, with decreased cardiac autonomic modulation in the first hour, regardless of obesity.

Magnitude and variation of ratio of total body potassium to fat-free mass: a cellular level modeling study

2001 ◽  
Vol 281 (1) ◽  
pp. E1-E7 ◽  
Author(s):  
Zimian Wang ◽  
F. Xavier Pi-Sunyer ◽  
Donald P. Kotler ◽  
Jack Wang ◽  
Richard N. Pierson ◽  
...  
Keyword(s):  
Body Fat ◽  
Essential Element ◽  
Physiological Model ◽  
Cellular Level ◽  
Fat Free Mass ◽  
Total Body Potassium ◽  
Fluid Compartment ◽  
Total Body Fat ◽  
Total Body ◽  
Living Organisms

Potassium is an essential element of living organisms that is found almost exclusively in the intracellular fluid compartment. The assumed constant ratio of total body potassium (TBK) to fat-free mass (FFM) is a cornerstone of the TBK method of estimating total body fat. Although the TBK-to-FFM (TBK/FFM) ratio has been assumed constant, a large range of individual and group values is recognized. The purpose of the present study was to undertake a comprehensive analysis of biological factors that cause variation in the TBK/FFM ratio. A theoretical TBK/FFM model was developed on the cellular body composition level. This physiological model includes six factors that combine to produce the observed TBK/FFM ratio. The ratio magnitude and range, as well as the differences in the TBK/FFM ratio between men and women and variation with growth, were examined with the proposed model. The ratio of extracellular water to intracellular water ( E/I) is the major factor leading to between-individual variation in the TBK/FFM ratio. The present study provides a conceptual framework for examining the separate TBK/FFM determinants and suggests important limitations of the TBK/FFM method used in estimating total body fat in humans and other mammals.

scholarly journals Smaller organ mass with greater age, except for heart

2009 ◽  
Vol 106 (6) ◽  
pp. 1780-1784 ◽  
Author(s):  
Qing He ◽  
Stanley Heshka ◽  
Jeanine Albu ◽  
Lawrence Boxt ◽  
Norman Krasnow ◽  
...  
Keyword(s):  
African Americans ◽  
The Elderly ◽  
Left Ventricular ◽  
Fat Free Mass ◽  
Whole Body ◽  
Organ Mass ◽  
Total Body ◽  
Age Range ◽  
Negative Relationships

Autopsy/cadaver data indicate that many organs and tissues are smaller in the elderly compared with young adults; however, in vivo data are lacking. The aim of this study was to determine whether the mass of specific high-metabolic-rate organs is different with increasing age, using MRI. Seventy-five healthy women (41 African-Americans and 34 Caucasians, age range 19–88 yr) and 36 men (8 African-Americans and 28 Caucasians, age range 19–84 yr) were studied. MRI-derived in vivo measures of brain, heart, kidneys, liver, and spleen were acquired. Left ventricular mass (LVM) was measured by either echocardiography or cardiac gated MRI. Total body fat mass and fat-free mass (FFM) were measured with a whole body dual-energy X-ray absorptiometry (DXA) scanner. Multiple regression analysis was used to investigate the association between the organ mass and age after adjustment for weight and height (or DXA measures of FFM), race, sex, and interactions among these variable. No statistically significant interaction was found among age, sex, and race in any regression model. Significant negative relationships between organ mass and age were found for brain ( P < 0.0001), kidneys ( P = 0.01), liver ( P = 0.001), and spleen ( P < 0.0001). A positive relationship between LVM and age was found after adjustment for FFM ( P = 0.037). These findings demonstrate that age has a significant effect on brain, kidneys, liver, spleen, and heart mass. The age effect was independent of race and sex.

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