scholarly journals Probiotics as a therapeutic strategy in obesity and overweight: a systematic review

2021 ◽  
Vol 12 (1) ◽  
pp. 5-15
Author(s):  
X.M. Tomé-Castro ◽  
M. Rodriguez-Arrastia ◽  
D. Cardona ◽  
L. Rueda-Ruzafa ◽  
G. Molina-Torres ◽  
...  

Obesity and overweight are two of the most health challenges with an increasing prevalence in recent years, in which several complications have been identified to have a high impact in patients’ health conditions. In this vein, an increasing interest in the gut microbiota has emerged as a target for therapeutic strategies in obesity and overweight due to its direct relation with the aforementioned health conditions and complications. Thus, the aim of this study was to evaluate the efficacy of probiotics as a therapeutic strategy in the management of obesity and overweight. A systematic review of randomised controlled trials was carried out in 6 databases until May 2019 to assess the use of probiotics in obesity and overweight patients. The Jadad Scale was used to assess the quality of the clinical trials. Twenty-three clinical trials published between 2000 and 2019 met the inclusion criteria. The role of probiotics in reducing body mass index and weight as well as changing the visceral abdominal fat area, waist and hip circumference were shown in 14 of 23 trials (60.87%); 14 trials (60.87%) showed changes on patients’ fatty acids and biomarkers; and 4 trials (17.39%) studied the role of the gut microbiota in obese and overweight patients. Some probiotics strains are shown to be effective in reducing body mass index and hip circumference. This review provides evidence of successful results in weight loss using probiotic groups.

2015 ◽  
Vol 64 (5) ◽  
pp. 87-95 ◽  
Author(s):  
Roman Victorovich Kapustin ◽  
Ol’ga Nikolaevna Arzhanova ◽  
Olesya Nikolaevna Bespalova ◽  
Vladimir Stepanovich Pakin ◽  
Andrey Gennadievich Kiselev

Objective: on the basis of a systematic review, clarify the role of overweight and obesity as a predictor of gestational diabetes mellitus (GDM). Materials and methods: an analysis of the literature data of the leading bibliographic sources - MEDLINE, Cochrane col., EMBASE. To evaluate the body mass index and standards of weight gain during pregnancy used the WHO guidelines and criteria of the Institute of Medicine (2009). The frequency and the odds ratio (OR) of developing GDM was estimated separately for each of the three groups in BMI. Results: A systematic review included 23 different design studies involving 740 510 women. It was found that the odds ratio of the risk of GDM in a group of pregnant women with excess weight is doubled - 2.22 (95 % CI 1.72 - 3.64), and almost four in obesity - 3.88 (95 % CI 2.97 - 5.32). The incidence of GDM in a group of pregnant women with normal body mass index - 3.77 % in the group with excess body weight - 6.59 %, in the group with obesity - 9.88 %. Conclusions: The obtained strong evidence of a direct connection between the linear increase in maternal BMI and the risk of developing gestational diabetes. Pregnant women with excess weight and obesity are at high risk for carbohydrate disorders during pregnancy.


2021 ◽  
Author(s):  
Meysam Zarezadeh ◽  
Azadeh Dehghani ◽  
Amir Hossein Faghfouri ◽  
Nima Radkhah ◽  
Mohammad Naemi Kermanshahi ◽  
...  

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e15559-e15559
Author(s):  
Sashidhar Manthravadi ◽  
Anuj Shrestha ◽  
Sheshadri Madhusudhana

2019 ◽  
Vol 20 (5-6) ◽  
pp. 356-367 ◽  
Author(s):  
Pingping Ning ◽  
Baiyuan Yang ◽  
Shuangjiang Li ◽  
Xin Mu ◽  
Qiuyan Shen ◽  
...  

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Sicong Wang ◽  
Xu Liu ◽  
Qixing Chen ◽  
Can Liu ◽  
Changshun Huang ◽  
...  

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