scholarly journals A Case of a Mesenteric Abscess Caused by Yersinia Infection

2021 ◽  
Vol 82 (1) ◽  
pp. 93-97
Author(s):  
Masaya TAKAHASHI ◽  
Mai KUWAHARA ◽  
Takumi TODA ◽  
Kayoko SHINSEKI ◽  
Akihiro KUSHIMA ◽  
...  
Keyword(s):  
Yersinia Infection

Role of strain differences on host resistance and the transcriptional response of macrophages to infection withYersinia enterocolitica

2006 ◽  
Vol 25 (1) ◽  
pp. 75-84 ◽  
Author(s):  
Katrin van Erp ◽  
Kristina Dach ◽  
Isabel Koch ◽  
Jürgen Heesemann ◽  
Reinhard Hoffmann
Keyword(s):  
Transcription Factors ◽  
Host Resistance ◽  
Genetic Background ◽  
Antibacterial Properties ◽  
Differentially Expressed ◽  
Transcriptional Responses ◽  
Yersinia Infection ◽  
Ifn Γ ◽  
The Impact

The outcome of a host-pathogen encounter is determined by virulence factors of the pathogen and defense factors of the host. We characterized the impact of host factors [resistant (C57BL/6) or susceptible (BALB/c) genetic background and exposure to interferon (IFN)-γ] on transcriptional responses of bone marrow-derived macrophages (BMDM) to infection with Yersinia enterocolitica. IFN-γ treatment more profoundly altered the transcriptome of BMDM than did bacterial infection or genetic background. In BALB/c BMDM, 1,161 genes were differentially expressed in response to Yersinia infection with or without IFN-γ prestimulation. Fourteen genes (1.2%) could only be induced by BALB/c BMDM in response to Yersinia infection after IFN-γ pretreatment. These genes inhibit apoptosis, activate NF-κB and Erk signaling, are chemotactic to neutrophils, and are involved in cytoskeletal reorganization, hence possibly in phagocytosis. Ten of these genes possess a common module of binding sites for Hox, Pou, and Creb transcription factors in 2 kb of upstream genomic sequence, suggesting a possible novel role of these transcription factors in regulation of immune responses. Fifty-two of one thousand fifty differentially expressed genes (4.9%) were induced more strongly by C57BL/6 BMDM in response to Yersinia infection than BALB/c BMDM. These genes activate NK cells, have antibacterial properties, or are involved in sensing chemokines and lipopolysaccharide (LPS). These data show that host resistance factors modulate a surprisingly small, but identifiable and functionally significant, portion of the macrophage transcriptome in response to Yersinia infection.

IgM, IgG, and IgA Antibodies in Yersinia Infection

1988 ◽  
Vol 157 (3) ◽  
pp. 601-602 ◽  
Author(s):  
K. Granfors ◽  
R. Lahesmaa-Rantala ◽  
A. Tonanen
Keyword(s):  
Yersinia Infection ◽  
Iga Antibodies

scholarly journals Hemochromatosis and Yersiniosis

1990 ◽  
Vol 4 (4) ◽  
pp. 160-162 ◽  
Author(s):  
Paul C Adams ◽  
James Gregor
Keyword(s):  
Iron Overload ◽  
Yersinia Enterocolitica ◽  
Hip Prosthesis ◽  
Systemic Infection ◽  
Simultaneous Occurrence ◽  
Yersinia Infection ◽  
Previously Treated

Two patients with documented hemochromatosis and systemic infection with Yersinia enterocolitica are described. The first patient presented with Y enterocolitica septicemia and an infected hip prosthesis which led to the diagnosis of hemochromatosis. The second patient was previously treated for Y enterocolitica with antibiotics but did not recover fully until aggressive phlebotomy therapy was started. The simultaneous occurrence of these two uncommon diseases is related to the ability of the yersinia organism to thrive in the presence of large amounts of iron. The association between iron overload and susceptibility to yersinia infection is reviewed within the context of these two cases.

Induction of cytotoxic CD8+ T cell after Yersinia infection of HLA-B27 transgenic rats: Evidence of restriction by rat class I MHC but not HLA-B27

1997 ◽  
Vol 56 ◽  
pp. 307
Author(s):  
G. Falgarone ◽  
H. Blanchard ◽  
B. Riot ◽  
J.D. Taurog ◽  
R.E. Hammer ◽  
...  
Keyword(s):  
T Cell ◽  
Cd8 T Cell ◽  
Class I ◽  
Hla B27 ◽  
Transgenic Rats ◽  
Class I Mhc ◽  
Yersinia Infection

Detection of Zoonotic Yersinia Infection in Symptomatic and Asymptomatic Dogs in Sokoto State Nigeria

2020 ◽  
Vol 1 (2) ◽  
Author(s):  
Nicholas Nathaniel Pilau ◽  
Shehu Zaid ◽  
Abubakar Sadiq Yakubu ◽  
Bashir Saidu ◽  
Umar , Yakubu Dabai ,
Keyword(s):  
Health Policy ◽  
Selective Medium ◽  
Selective Media ◽  
Yersinia Species ◽  
Yersinia Infection ◽  
Animal Populations ◽  
Pure Cultures ◽  
Animal Hosts ◽  
Relative Prevalence ◽  
Suspicion Index

Background: Zoonotic Yersinia infection has been previously reported in humans and animal hosts in Nigeria, occasionally with fulminant disease. Despite earlier evidence of Yersinia pathogen circulating in human and animal populations in Nigeria, studies and suspicion index to Yersinia is below an acceptable average amongst clinicians, diagnosticians, academics and health policy officers. Methods: The deoxycholate Citrate Agar (DCA) was used as a selective media to culture Yersinia, preceded by inoculation in MacConkay agar. Plates with evident growth in the differential media consistent with reported accounts for Yersinia were picked and inoculated in selective medium and left for 48 hours until growth was seen, other samples were left until five days before being discarded as negative. Pure cultures were subjected to a comprehensive biochemical test standard and previously applied for diagnosis and discrimination of Yersinia species. Result: This research recorded an overall microbial prevalence of 30%. Prevalence of Yersinia enterocolitica was 18.3% and Y. pseudotuberculosis 11.7%. Male dogs presented a relative prevalence of Y. enterocolitica 40.9% compared with 59.1% recorded for female dogs. Symptomatic dogs presented a relative prevalence of Y. enterocolitica of 86.4% and Y. pseudotuberculosis of 71.4%

Yersinia infection mimicking recurrence of gastrointestinal stromal tumor

2004 ◽  
Vol 39 (6) ◽  
pp. 609-612 ◽  
Author(s):  
T. Luedde ◽  
F. Tacke ◽  
A. Chavan ◽  
F. Länger ◽  
J. Klempnauer ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Stromal Tumor ◽  
Yersinia Infection
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