scholarly journals A Case of Primary Hepatic Neuroendocrine Tumor with Suspected Bile Duct Invasion and Difficulty in Preoperative Diagnosis

2021 ◽  
Vol 82 (1) ◽  
pp. 151-158
Author(s):  
Hisato YAMAMOTO ◽  
Kohei OGAWA ◽  
Kei TAMURA ◽  
Katsunori SAKAMOTO ◽  
Akihiro TAKAI ◽  
...  
Keyword(s):  
Bile Duct ◽  
Neuroendocrine Tumor ◽  
Preoperative Diagnosis ◽  
Bile Duct Invasion ◽  
Primary Hepatic Neuroendocrine Tumor

scholarly journals A Case of Primary Hepatic Neuroendocrine Tumor and Literature Review

2021 ◽  
pp. 90-97
Author(s):  
Pak Chiu Wong ◽  
Wong Hoi She ◽  
Ui Soon Khoo ◽  
Tan To Cheung
Keyword(s):  
Liver Resection ◽  
Neuroendocrine Tumor ◽  
Preoperative Diagnosis ◽  
Radionuclide Therapy ◽  
Tumor Recurrence ◽  
Peptide Receptor Radionuclide Therapy ◽  
Rare Tumor ◽  
Major Liver Resection ◽  
Peptide Receptor ◽  
Primary Hepatic Neuroendocrine Tumor

We report an unusual presentation of primary hepatic neuroendocrine tumor which was initially misdiagnosed as intrahepatic cholangiocarcinoma. The diagnosis was only revealed after a major liver resection by histopathology. With adjuvant lanreotide injection, the patient survived for more than 16 months after the operation without tumor recurrence. Diagnosis of this rare tumor has been a major challenge and we emphasize the importance of a preoperative diagnosis. Surgical resection remains the mainstay for curative treatment, while peptide receptor radionuclide therapy is an emerging treatment option which has provided promising results.

scholarly journals Obstructive Jaundice Following Transarterial Chemoembolization for Hepatocellular Carcinoma with Bile Duct Invasion

2021 ◽  
Vol 5 (02) ◽  
pp. 127-130
Author(s):  
Kazuki Matsushita ◽  
Ken Kageyama ◽  
Natsuhiko Kameda ◽  
Yurina Koizumi ◽  
Akira Yamamoto
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bile Duct ◽  
Obstructive Jaundice ◽  
Transarterial Chemoembolization ◽  
Tumor Invasion ◽  
Endoscopic Sphincterotomy ◽  
Biliary Obstruction ◽  
Intraductal Tumor ◽  
Bile Duct Invasion ◽  
The Common

AbstractHepatocellular carcinoma (HCC) with bile duct invasion is considered rare. A case in which a fragment of intraductal tumor dropped into the common bile duct after transarterial chemoembolization (TACE) and caused abdominal pain, and obstructive jaundice secondary to biliary obstruction is presented. This case was successfully managed by emergent endoscopic sphincterotomy. Physicians should recognize one of the complications due to TACE for HCC with intraductal tumor invasion.

scholarly journals Neuroendocrine tumor of distal bile duct

2016 ◽  
Vol 72 ◽  
pp. S101-S104 ◽  
Author(s):  
J.K. Banerjee ◽  
R. Saranga Bharathi ◽  
Sharad Shrivastava ◽  
Praveer Ranjan
Keyword(s):  
Bile Duct ◽  
Neuroendocrine Tumor ◽  
Distal Bile Duct

scholarly journals Primary Hepatic Neuroendocrine Tumor with Unusual Thyroid Follicular-Like Morphologic Characteristics

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Mohd Elmugtaba Ibrahim ◽  
Kerolos Abadeer ◽  
Qihui (Jim) Zhai ◽  
Aziza Nassar
Keyword(s):  
Liver Transplant ◽  
Neuroendocrine Tumor ◽  
Wedge Resection ◽  
Unknown Origin ◽  
Thyroid Tumor ◽  
Intermediate Grade ◽  
Morphologic Characteristics ◽  
Ischemic Cholangiopathy ◽  
Metastatic Neuroendocrine Tumor ◽  
Primary Hepatic Neuroendocrine Tumor

We describe a primary hepatic neuroendocrine tumor of a 57-year-old Thai woman who presented in 2004 with a suspicious mass in the left hepatic lobe. She underwent left hepatectomy for the 10.5-cm mass, calledintermediate grade neuroendocrine carcinoma of unknown origin,likely metastatic. The tumor recurred in 2007, then calledrecurrent primary hepatic neuroendocrine tumor(PHNET), and the patient underwent liver transplant. Because of similarity between the neuroendocrine tumor and a thyroid tumor—specifically, follicular-like characteristics—immunohistochemical stains for thyroglobulin, TTF1, and calcitonin were performed. However, all were negative. All imaging studies revealed no evidence of a primary lesion other than the liver mass. In 2008, the patient’s liver transplant failed because of ischemic cholangiopathy, and she underwent a second liver transplant. Seven years later, in 2015, she presented with metastatic neuroendocrine tumor of intermediate grade to the lung, consistent with metastatic PHNET. She underwent left upper-lobe wedge resection to remove the tumor. The patient is alive with no evidence of disease at 13 years after initial diagnosis. This rare variant of PHNET had thyroid-like morphologic characteristics but there is no evidence of primary thyroid tumor or thyroid markers in the primary and recurrent hepatic tumors and lung metastasis.

scholarly journals Difficulty Achieving a Preoperative Diagnosis of IgG4-Related Sclerosing Cholangitis

2018 ◽  
Vol 12 (2) ◽  
pp. 425-431
Author(s):  
Kazuhiro Suzumura ◽  
Etsuro Hatano ◽  
Masaharu Tada ◽  
Hideaki Sueoka ◽  
Hiroshi Nishida ◽  
...  
Keyword(s):  
Bile Duct ◽  
Preoperative Diagnosis ◽  
Sclerosing Cholangitis ◽  
Wall Thickening ◽  
Distal Bile Duct ◽  
Obliterative Phlebitis ◽  
Bile Duct Stenosis ◽  
Storiform Fibrosis ◽  
Lymphoplasmacytic Infiltration ◽  
Duct Stenosis

A 75-year-old male was admitted to our hospital because of bile duct stenosis. He had no medical history of autoimmune disease. The level of tumor markers, serum IgG, and IgG4 were within normal ranges. Computed tomography showed perihilar and distal bile duct stenosis and wall thickening without swelling or abnormal enhancement of the pancreas. Endoscopic retrograde cholangiopancreatography showed perihilar and distal bile duct stenosis. A biopsy and cytology from the distal bile duct stenosis suggested adenocarcinoma, and cytology from the perihilar bile duct also suggested adenocarcinoma. A preoperative diagnosis of perihilar and distal bile duct cancer was made, and the patient underwent left hepatectomy and pancreaticoduodenectomy. Resected specimens showed wall thickening in the perihilar and distal bile duct; however, tumors were unclear. A histopathological examination revealed lymphoplasmacytic infiltration, storiform fibrosis, and obliterative phlebitis in the perihilar and distal bile ducts. Immunohistochemistry revealed diffuse infiltration of IgG4-positive plasma cells in the perihilar and distal bile ducts. Lymphoplasmacytic infiltration, inflammatory change, storiform fibrosis, and obliterative phlebitis were shown in the pancreas. A final diagnosis of IgG4-related sclerosing cholangitis (IgG4-SC) with autoimmune pancreatitis was made. We herein report a case in which a preoperative diagnosis of IgG4-SC was difficult due to normal serum IgG4 levels and no obvious pancreatic lesion.

scholarly journals Abordaje laparoscópico sistemático de la coledocolitiasis

2021 ◽  
Vol 113 (1) ◽  
pp. 62-72
Author(s):  
Carlos M. Canullán ◽  
◽  
Enrique J. Petracchi ◽  
Nicolás Baglietto ◽  
Hugo I. Zandalazini ◽  
...  
Keyword(s):  
Laparoscopic Surgery ◽  
Bile Duct ◽  
Common Bile Duct ◽  
Preoperative Diagnosis ◽  
Length Of Hospital Stay ◽  
Common Bile Duct Stones ◽  
Single Stage ◽  
Bile Duct Stones ◽  
Bile Duct Injuries ◽  
Transcystic Approach

Background: The prevalence of common bile duct stones associated with cholelithiasis increases with age and is about 15 % in the 8th decade of life but its management is still controversial. Some surgeons prefer the single-stage approach with laparoscopy while others suggest the two-stage management with preoperative endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic cholecystectomy. Objective: The aim of the present study was to evaluate the efficacy of feasibility of single-stage laparoscopic surgery in patients with cholelithiasis and choledocholithiasis. Material and methods: We conducted a retrospective study with prospectively collected data between July 2008 and July 2018. Results: Of 2447 laparoscopic cholecystectomies performed during the study period, 416 presented common bile duct stones. The global success of the transcystic approach to clear common bile duct stones was 81.2%, 70.4% in the cases with preoperative diagnosis of choledocholithiasis and 92.9% for other diagnoses. The rate of complications was 4% without deaths or bile duct injuries. Conclusion: Single-stage laparoscopic surgery is an efficient and safe approach based on the high global success of transcystic exploration. The preoperative diagnosis of choledocholithiasis reduces the efficacy of the procedure due to greater indication of choledocotomy, with complications and longer length of hospital stay.

scholarly journals A Case of Primary Hepatic Neuroendocrine Tumor with Multiple Intrahepatic Metastases Aiding Long-term Survival

2018 ◽  
Vol 79 (4) ◽  
pp. 858-863 ◽  
Author(s):  
Masaru SASAKI ◽  
Hiroyuki NAKABA ◽  
Hiroshi TAMAGAWA ◽  
Hiroyuki KIKKAWA ◽  
Eiji TANIGUCHI ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Term Survival ◽  
Long Term Survival ◽  
Primary Hepatic Neuroendocrine Tumor

scholarly journals Two Cases of Primary Hepatic Neuroendocrine Tumor

2018 ◽  
Vol 43 (2) ◽  
pp. 239-246 ◽  
Author(s):  
Yusuke Koda ◽  
Yusuke Ome ◽  
Kenichi Saga ◽  
Kazuyuki Kawamoto
Keyword(s):  
Neuroendocrine Tumor ◽  
Primary Hepatic Neuroendocrine Tumor

scholarly journals Neuroendocrine tumor of the common bile duct: a case report and review of the literature

2018 ◽  
Vol Volume 11 ◽  
pp. 2295-2301 ◽  
Author(s):  
Zhong Liu ◽  
Deng-Yong Zhang ◽  
Zheng Lu ◽  
Pei Zhang ◽  
Wan-Liang Sun ◽  
...  
Keyword(s):  
Case Report ◽  
Bile Duct ◽  
Common Bile Duct ◽  
Neuroendocrine Tumor ◽  
Review Of The Literature ◽  
The Common
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