scholarly journals Two Cases of Primary Hepatic Neuroendocrine Tumor

2018 ◽  
Vol 43 (2) ◽  
pp. 239-246 ◽  
Author(s):  
Yusuke Koda ◽  
Yusuke Ome ◽  
Kenichi Saga ◽  
Kazuyuki Kawamoto
Keyword(s):  
Neuroendocrine Tumor ◽  
Primary Hepatic Neuroendocrine Tumor

scholarly journals A Case of Primary Hepatic Neuroendocrine Tumor and Literature Review

2021 ◽  
pp. 90-97
Author(s):  
Pak Chiu Wong ◽  
Wong Hoi She ◽  
Ui Soon Khoo ◽  
Tan To Cheung
Keyword(s):  
Liver Resection ◽  
Neuroendocrine Tumor ◽  
Preoperative Diagnosis ◽  
Radionuclide Therapy ◽  
Tumor Recurrence ◽  
Peptide Receptor Radionuclide Therapy ◽  
Rare Tumor ◽  
Major Liver Resection ◽  
Peptide Receptor ◽  
Primary Hepatic Neuroendocrine Tumor

We report an unusual presentation of primary hepatic neuroendocrine tumor which was initially misdiagnosed as intrahepatic cholangiocarcinoma. The diagnosis was only revealed after a major liver resection by histopathology. With adjuvant lanreotide injection, the patient survived for more than 16 months after the operation without tumor recurrence. Diagnosis of this rare tumor has been a major challenge and we emphasize the importance of a preoperative diagnosis. Surgical resection remains the mainstay for curative treatment, while peptide receptor radionuclide therapy is an emerging treatment option which has provided promising results.

scholarly journals Primary Hepatic Neuroendocrine Tumor with Unusual Thyroid Follicular-Like Morphologic Characteristics

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Mohd Elmugtaba Ibrahim ◽  
Kerolos Abadeer ◽  
Qihui (Jim) Zhai ◽  
Aziza Nassar
Keyword(s):  
Liver Transplant ◽  
Neuroendocrine Tumor ◽  
Wedge Resection ◽  
Unknown Origin ◽  
Thyroid Tumor ◽  
Intermediate Grade ◽  
Morphologic Characteristics ◽  
Ischemic Cholangiopathy ◽  
Metastatic Neuroendocrine Tumor ◽  
Primary Hepatic Neuroendocrine Tumor

We describe a primary hepatic neuroendocrine tumor of a 57-year-old Thai woman who presented in 2004 with a suspicious mass in the left hepatic lobe. She underwent left hepatectomy for the 10.5-cm mass, calledintermediate grade neuroendocrine carcinoma of unknown origin,likely metastatic. The tumor recurred in 2007, then calledrecurrent primary hepatic neuroendocrine tumor(PHNET), and the patient underwent liver transplant. Because of similarity between the neuroendocrine tumor and a thyroid tumor—specifically, follicular-like characteristics—immunohistochemical stains for thyroglobulin, TTF1, and calcitonin were performed. However, all were negative. All imaging studies revealed no evidence of a primary lesion other than the liver mass. In 2008, the patient’s liver transplant failed because of ischemic cholangiopathy, and she underwent a second liver transplant. Seven years later, in 2015, she presented with metastatic neuroendocrine tumor of intermediate grade to the lung, consistent with metastatic PHNET. She underwent left upper-lobe wedge resection to remove the tumor. The patient is alive with no evidence of disease at 13 years after initial diagnosis. This rare variant of PHNET had thyroid-like morphologic characteristics but there is no evidence of primary thyroid tumor or thyroid markers in the primary and recurrent hepatic tumors and lung metastasis.

scholarly journals A Case of Primary Hepatic Neuroendocrine Tumor with Multiple Intrahepatic Metastases Aiding Long-term Survival

2018 ◽  
Vol 79 (4) ◽  
pp. 858-863 ◽  
Author(s):  
Masaru SASAKI ◽  
Hiroyuki NAKABA ◽  
Hiroshi TAMAGAWA ◽  
Hiroyuki KIKKAWA ◽  
Eiji TANIGUCHI ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Term Survival ◽  
Long Term Survival ◽  
Primary Hepatic Neuroendocrine Tumor

Primary Hepatic Neuroendocrine Tumor

2019 ◽  
Vol 44 (1) ◽  
pp. 88-90 ◽  
Author(s):  
Xia Bai ◽  
Xia Zhang ◽  
Xuemei Wang
Keyword(s):  
Neuroendocrine Tumor ◽  
Primary Hepatic Neuroendocrine Tumor

scholarly journals Case Report of Contrast-Enhanced Ultrasound Features of Primary Hepatic Neuroendocrine Tumor

Medicine ◽  
2016 ◽  
Vol 95 (21) ◽  
pp. e3450 ◽  
Author(s):  
Wei Li ◽  
Bo-wen Zhuang ◽  
Zhu Wang ◽  
Bing Liao ◽  
Ling-yao Hong ◽  
...  
Keyword(s):  
Case Report ◽  
Neuroendocrine Tumor ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Primary Hepatic Neuroendocrine Tumor ◽  
Ultrasound Features

scholarly journals Primary hepatic neuroendocrine tumor: A case report

2016 ◽  
Vol 4 (6) ◽  
pp. 954-956 ◽  
Author(s):  
ASAHIRO MORISHITA ◽  
HIROHITO YONEYAMA ◽  
TAKAKO NOMURA ◽  
TEPPEI SAKAMOTO ◽  
KOJI FUJITA ◽  
...  
Keyword(s):  
Case Report ◽  
Neuroendocrine Tumor ◽  
Primary Hepatic Neuroendocrine Tumor

scholarly journals Primary hepatic neuroendocrine tumor

2021 ◽  
Vol 2021 ◽  
Author(s):  
Le Tuan Linh ◽  
Nguyen Minh Duc ◽  
Hoang Tu Minh ◽  
Nguyen Ngoc Cuong ◽  
Vuong Thu Ha ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Clinical Symptoms ◽  
Final Diagnosis ◽  
List Type ◽  
Rare Type ◽  
Imaging Characteristics ◽  
Imaging Results ◽  
Long Term Follow Up ◽  
Conclusive Diagnosis ◽  
Primary Hepatic Neuroendocrine Tumor

Summary Primary hepatic neuroendocrine tumor (PHNET) is a rare type of neuroendocrine tumor (NET) that is also a primary hepatic tumor. Patients are present with almost no specific clinical symptoms and typically present with negative test results and atypical imaging characteristics; therefore, the differentiation of PHNET from other types of primary hepatic masses can be very difficult. In this article, we describe a case of PHNET that mimicked a liver helminth infection in a 57-year-old man. The diagnosis of PHNET in this patient was challenging, and the final diagnosis was based on imaging, histopathology features, and long-term follow-up. Learning points An uncommon type of neuroendocrine tumor (NET) is a primary hepatic neuroendocrine tumor (PHNET). Primary hepatic neuroendocrine tumors are rare NET lesions found in the liver, characterized by non-specific clinical and imaging results, which can be easily confused with other liver lesions, including HCC and parasitic lesions. To have a conclusive diagnosis and classification, a mixture of many medical assessment techniques, such as imaging, gastrointestinal endoscopy, nuclear medicine, anatomy, including histopathology, and immunohistochemistry, is essential.

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