scholarly journals A Case Report of Laparoscopic Abdominal Lymphadenectomy as Salvage Surgery for Lymph Node Recurrence following Definitive Chemoradiotherapy for Esophageal Cancer

2014 ◽  
Vol 75 (4) ◽  
pp. 934-940
Author(s):  
Keisuke KAWAMORITA ◽  
Masahiro NIIHARA ◽  
Masafumi IE ◽  
Yasuhiro TSUBOSA ◽  
Masanori TOKUNAGA ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Case Report ◽  
Lymph Node ◽  
Salvage Surgery ◽  
Definitive Chemoradiotherapy ◽  
Lymph Node Recurrence

scholarly journals Definitive Chemoradiotherapy and Salvage Esophagectomy for Esophageal Cancer Associated With Multiple Lung Metastases: A Case Report

2014 ◽  
Vol 99 (5) ◽  
pp. 640-644
Author(s):  
Yoshihiko Fujinaka ◽  
Masaru Morita ◽  
Takefumi Ohga ◽  
Yoshihiro Kakeji ◽  
Tokujiro Yano ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Case Report ◽  
Distant Metastasis ◽  
Multimodal Therapy ◽  
Lung Metastases ◽  
Salvage Surgery ◽  
Complete Response ◽  
Definitive Chemoradiotherapy ◽  
Node Metastases ◽  
Salvage Esophagectomy

Abstract The prognosis of esophageal cancer with distant metastasis is dismal. We report a 70-year-old man with esophageal cancer and multiple lung and lymph node metastases. Complete response was achieved following definitive chemoradiotherapy. Twenty-four months after the initial chemoradiotherapy, local recurrence was detected but there was no evidence of distant metastasis. Therefore, the patient underwent salvage esophagectomy. The surgery was well tolerated without any postoperative complications. The patient is still alive 48 months after the salvage surgery. Our experience suggests that salvage esophagectomy is an important component of multimodal therapy for the recurrence of esophageal cancer.

Laparoscopic dissection for pelvic lymph node recurrence of thymic carcinoma: A case report

2019 ◽  
Vol 13 (1) ◽  
pp. 107-110
Author(s):  
Takahiko Akiyama ◽  
Yuji Miyamoto ◽  
Daichi Nomoto ◽  
Yuki Kiyozumi ◽  
Kojiro Eto ◽  
...  
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Thymic Carcinoma ◽  
Pelvic Lymph Node ◽  
Lymph Node Recurrence

RA10.04: POSTOPERATIVE PNEUMONIA IS ASSOCIATED WITH SHORT-TERM AND LONG-TERM MORTALITY OF DEFINITIVE CHEMORADIOTHERAPY FOLLOWED BY SALVAGE ESOPHAGECTOMY FOR ESOPHAGEAL CANCER

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 43-43
Author(s):  
Masashi Takeuchi ◽  
Hirofumi Kawakubo ◽  
Shuhei Mayanagi ◽  
Kazumasa Fukuda ◽  
Rieko Nakamura ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Prognostic Factors ◽  
Prediction Model ◽  
Salvage Surgery ◽  
Postoperative Pneumonia ◽  
Short Term ◽  
Definitive Chemoradiotherapy ◽  
Invasive Approach ◽  
Salvage Esophagectomy

Abstract Background Although definitive chemoradiotherapy (CRT) with salvage esophagectomy has improved overall survival (OS) for esophageal cancer, it is a more invasive approach than neoadjuvant CRT followed by surgery or surgery alone, and causes high mortality after surgery. The purpose of this study was to investigate the short and long-term outcomes of salvage esophagectomy, to determine their prognostic factors, and to create a prediction model for OS using a classification and regression tree (CART). Methods Ninety patients who had undergone CRT followed by esophagectomy for thoracic esophageal cancer at Keio University Hospital, Tokyo, Japan, between June 1994 and August 2014 were identified for this study. We divided the 90 patients into two groups—the salvage group and the neoadjuvant group—according to the dose of irradiation of CRT. Forty-four patients who underwent CRT with radiation dose less than 50 Gy, followed by planned esophagectomy, were allocated to the neoadjuvant group. Forty-six patients with salvage esophagectomy for locally recurrent or residual cancer after definitive CRT (greater than 50 Gy) were allocated to the salvage group. Results Patients from the salvage group tended to have a lower OS (median survival: Salvage, 25 months vs neoadjuvant, 50 months, P = 0.149). In the salvage group, pneumonia and age were identified as factors predictive of in-hospital mortality. OS was significantly lower in patients with postoperative pneumonia and female gender. We set the prediction model for OS in the salvage group using survival CART. The group of R1/2 resection aged ≥ 56.5 years and the group suffering from postoperative pneumonia were the groups at highest risk; the area under the curve was 0.72. Conclusion The present study demonstrates the short-term and long-term prognostic factors of salvage esophagectomy after definitive CRT for esophageal cancer. Achieving improvement in OS after salvage surgery requires increased R0 resection rates and decreased pulmonary complications. Both informed decision making in the adoption of salvage surgery and specific plans to reduce pneumonia through means such as pulmonary rehabilitation are required. Disclosure All authors have declared no conflicts of interest.

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