scholarly journals Comparison of the effect of bipolar coagulation and fibrillar structured oxidized cellulose on formation epidural fibrosis in rats

2021 ◽  
Keyword(s):  
Oxidized Cellulose ◽  
Epidural Fibrosis ◽  
Bipolar Coagulation

scholarly journals Topping Phenomenon with Recurrent Spinal Stenosis and Epidural Fibrosis Prevented with Oxidized Cellulose – a Case Report

2018 ◽  
Vol 61 (2) ◽  
pp. 69-73 ◽  
Author(s):  
Radek Hart
Keyword(s):  
Case Report ◽  
Lumbar Spine ◽  
Spinal Stenosis ◽  
Lumbar Spinal Stenosis ◽  
Oxidized Cellulose ◽  
Epidural Fibrosis ◽  
Nerve Roots ◽  
Failed Back Syndrome ◽  
Dural Sac ◽  
Lumbar Spinal

Lumbar spinal stenosis is a condition where the neural structures are compressed in the narrowed spinal canal and often situated only within a single specific segment of the spine, most frequently in the lumbar spine. A case report demonstrates a surgical solution of lumbar spinal stenosis with using oxidized cellulose as a prevention of post-operative adhesions and failed back syndrome. A female patient (68) with a significant pain of the lumbar spine lasting for a number of months due to advanced spondylosis, failing to respond to conservative treatment underwent instrumented, posterolateral fusion of affected segments. The patient re-arrived with pain due to spinal stenosis in another segments after 4 and then after 3 years. We repeatedly performed spinal fusion of the affected segments and applied an antiadhesive gel to the dural sac and the decompressed nerve roots to prevent the development of post-operative adhesions and the “failed back syndrome”. Last surgical solution included mobilisation of the simultaneously constricted dural sac through laminectomy. This time we covered the sac using a haemostat made of oxidized cellulose (Traumacel FAM). After this treatment, the patient was again without significant difficulties.

Effect of in Vivo Oxidized Cellulose on in Vitro Growth of Human Respiratory Mucosa and Sub-mucosa During Endoscopic Skull Base Approaches

2016 ◽  
Vol 77 (S 01) ◽  
Author(s):  
Ezequiel Goldschmidt ◽  
Jorge Rasmussen ◽  
Joseph Chabot ◽  
Monica Loressi ◽  
Marcelo Ielpi ◽  
...  
Keyword(s):  
Skull Base ◽  
Oxidized Cellulose ◽  
In Vitro Growth ◽  
Respiratory Mucosa

scholarly journals Lumbar Interbody Fusion Conducted on a Porcine Model with a Bioresorbable Ceramic/Biopolymer Hybrid Implant Enriched with Hyperstable Fibroblast Growth Factor 2

Biomedicines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 733
Author(s):  
Milan Krticka ◽  
Ladislav Planka ◽  
Lucy Vojtova ◽  
Vladimir Nekuda ◽  
Premysl Stastny ◽  
...  
Keyword(s):  
Growth Factor ◽  
Lumbar Fusion ◽  
Biomechanical Testing ◽  
Fibroblast Growth Factor 2 ◽  
Oxidized Cellulose ◽  
Fibroblast Growth ◽  
Micro Ct ◽  
Bone Autograft ◽  
Autograft Group

Many growth factors have been studied as additives accelerating lumbar fusion rates in different animal models. However, their low hydrolytic and thermal stability both in vitro and in vivo limits their workability and use. In the proposed work, a stabilized vasculogenic and prohealing fibroblast growth factor-2 (FGF2-STAB®) exhibiting a functional half-life in vitro at 37 °C more than 20 days was applied for lumbar fusion in combination with a bioresorbable scaffold on porcine models. An experimental animal study was designed to investigate the intervertebral fusion efficiency and safety of a bioresorbable ceramic/biopolymer hybrid implant enriched with FGF2-STAB® in comparison with a tricortical bone autograft used as a gold standard. Twenty-four experimental pigs underwent L2/3 discectomy with implantation of either the tricortical iliac crest bone autograft or the bioresorbable hybrid implant (BHI) followed by lateral intervertebral fixation. The quality of spinal fusion was assessed by micro-computed tomography (micro-CT), biomechanical testing, and histological examination at both 8 and 16 weeks after the surgery. While 8 weeks after implantation, micro-CT analysis demonstrated similar fusion quality in both groups, in contrast, spines with BHI involving inorganic hydroxyapatite and tricalcium phosphate along with organic collagen, oxidized cellulose, and FGF2- STAB® showed a significant increase in a fusion quality in comparison to the autograft group 16 weeks post-surgery (p = 0.023). Biomechanical testing revealed significantly higher stiffness of spines treated with the bioresorbable hybrid implant group compared to the autograft group (p < 0.05). Whilst histomorphological evaluation showed significant progression of new bone formation in the BHI group besides non-union and fibrocartilage tissue formed in the autograft group. Significant osteoinductive effects of BHI based on bioceramics, collagen, oxidized cellulose, and FGF2-STAB® could improve outcomes in spinal fusion surgery and bone tissue regeneration.

scholarly journals Nonisocyanate Poly(Hydroxyl Urethane)-Based Green Polymer Hybrid Coating Systems: Tailoring of Biomacromolecular Compound Architecture Using APTMS-ZnO/TEMPO-Oxidized Cellulose Nanoparticles

ACS Omega ◽  
2020 ◽  
Vol 5 (18) ◽  
pp. 10315-10326 ◽  
Author(s):  
Mhd. Abd. Cader Mhd. Haniffa ◽  
Hazlee Azil Illias ◽  
Ching Yern Chee ◽  
Shaliza Ibrahim ◽  
Viorel Sandu ◽  
...  
Keyword(s):  
Hybrid Coating ◽  
Oxidized Cellulose ◽  
Cellulose Nanoparticles ◽  
Polymer Hybrid ◽  
Green Polymer

TEMPO-oxidized cellulose poly-ionic drawn fiber, a cell support system proof of concept

2021 ◽  
Author(s):  
Mariana Alves Rios ◽  
Paula Aboud Barbugli ◽  
Mônica Rosas Costa Iemma ◽  
Rafael Grande ◽  
Antônio José Felix Carvalho ◽  
...  
Keyword(s):  
Support System ◽  
Oxidized Cellulose ◽  
Proof Of Concept ◽  
A Cell ◽  
Cell Support

scholarly journals Rapid Water Softening with TEMPO-Oxidized/Phosphorylated Nanopapers

Nanomaterials ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 136 ◽  
Author(s):  
Andreas Mautner ◽  
Thawanrat Kobkeatthawin ◽  
Florian Mayer ◽  
Christof Plessl ◽  
Selestina Gorgieva ◽  
...  
Keyword(s):  
Adsorption Capacity ◽  
Cellulose Nanofibrils ◽  
Water Hardness ◽  
Organic Liquids ◽  
Oxidized Cellulose ◽  
Water Softening ◽  
Aqueous Suspensions ◽  
Overall Performance ◽  
Exchange Resins ◽  
Very High

Water hardness not only constitutes a significant hazard for the functionality of water infrastructure but is also associated with health concerns. Commonly, water hardness is tackled with synthetic ion-exchange resins or membranes that have the drawbacks of requiring the awkward disposal of saturated materials and being based on fossil resources. In this work, we present a renewable nanopaper for the purpose of water softening prepared from phosphorylated TEMPO-oxidized cellulose nanofibrils (PT-CNF). Nanopapers were prepared from CNF suspensions in water (PT-CNF nanopapers) or low surface tension organic liquids (ethanol), named EPT-CNF nanopapers, respectively. Nanopaper preparation from ethanol resulted in a significantly increased porosity of the nanopapers enabling much higher permeances: more than 10,000× higher as compared to nanopapers from aqueous suspensions. The adsorption capacity for Ca2+ of nanopapers from aqueous suspensions was 17 mg g−1 and 5 mg g−1 for Mg2+; however, EPT-CNF nanopapers adsorbed more than 90 mg g−1 Ca2+ and almost 70 mg g−1 Mg2+. The higher adsorption capacity was a result of the increased accessibility of functional groups in the bulk of the nanopapers caused by the higher porosity of nanopapers prepared from ethanol. The combination of very high permeance and adsorption capacity constitutes a high overall performance of these nanopapers in water softening applications.

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