scholarly journals Metabolism of irinotecan and its active metabolite SN-38 by intestinal microflora in rats

1994 ◽  
Vol 20 (4) ◽  
Author(s):  
Masuda
Keyword(s):  
Active Metabolite ◽  
Intestinal Microflora

Inhibition of intestinal microflora β-glucuronidase modifies the distribution of the active metabolite of the antitumor agent, irinotecan hydrochloride (CPT-11) in rats

1998 ◽  
Vol 42 (4) ◽  
pp. 280-286 ◽  
Author(s):  
Kiyoshi Takasuna ◽  
Takehiro Hagiwara ◽  
Masaaki Hirohashi ◽  
Michiyuki Kato ◽  
Mamoru Nomura ◽  
...  
Keyword(s):  
Active Metabolite ◽  
Intestinal Microflora ◽  
Antitumor Agent ◽  
Irinotecan Hydrochloride

Biological and chemical assessment of vermitrasporin, an anti-TB active metabolite from the fungus MSX 105528

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
CH Hwang ◽  
BU Jaki ◽  
JG Napolitano ◽  
DC Lankin ◽  
J McAlpine ◽  
...  
Keyword(s):  
Active Metabolite ◽  
Chemical Assessment

The role of the active metabolite of vitamin D (alfacalcidol) in the treatment of deficiency states and functional disorders

2015 ◽  
Vol 17 (9) ◽  
pp. 139-143
Author(s):  
I.S. Dydykina ◽  
◽  
P.S. Dydykina ◽  
A.A. Kovalenko ◽  
◽  
...  
Keyword(s):  
Vitamin D ◽  
Active Metabolite ◽  
Functional Disorders

Productivity and technological qualities of pork when using biological drugs

2020 ◽  
pp. 12-28
Author(s):  
O. Mikheeva ◽  
V. Fedyuk ◽  
M. Slozhenkina
Keyword(s):  
Endocrine Cells ◽  
Intestinal Microflora ◽  
Biologically Active ◽  
Large White ◽  
Biological Drugs ◽  
Animal Blood ◽  
Intestinal Microbiology ◽  
White Breed ◽  
Meat Productivity

In world practice biologically active drugs are widely used at different technological stages of rearing pigs, poultry and cattle. Special attention should be paid to bio-grugs obtained not as a result of chemical synthesis, but isolated from organs and tissues of healthy animals. Restoration of normal intestinal microflora of the animal is the basis of the concept of probiotics. Currently, probiotics are considered as endogenous intestinal microflora most often belonging to the group of lactobacilli, streptococci or bifidobacteria or as specific growth factors for them. Probiotics are selected according to certain criteria based on scientific knowledge of the physiology of intestinal microbiology, as well as animal nutrition. The purpose of the work was to study the effect of biological products on resistance, reproductive, fattening and meat productivity of pigs, on the quality of whole-muscle and fine-structured pork products; to develop a method of application of duodenum extract in combination with probiotics to increase the productivity of pigs. Studies on the effect of extracts derived from endocrine cells of the intestine, in combination with probiotics on the productivity of pigs of Large White breed and the quality of pork, as well as studied the effect of duodenins and probiotics in different concentrations on the protective properties of animal blood have been carried out. New methods of application of extracts of endocrine cells of intestines and probiotics for increase of meat productivity of animals and quality of pork have been offered. The use of bio-drugs increased the livability of young animals in all experimental groups from 1st to 4st by 3,51; 6,05; 4,95 and 5,90 %, respectively. There was an advantage in the amount of revenue from the sale of products of all experimental groups over the control one.

Influence ofLactobacillusF19 on Intestinal Microflora in Children and Elderly Persons and Impact onHelicobacter pyloriInfections

2002 ◽  
Vol 14 (1) ◽  
Author(s):  
Åsa Sullivan ◽  
Rutger Bennet ◽  
Matti Viitanen ◽  
Ann-Chatrin Palmgren ◽  
Carl Erik Nord
Keyword(s):  
Intestinal Microflora ◽  
Elderly Persons
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