The role of growth factors in proliferation and invasion of thyroid cancer

1997 ◽  
Author(s):  
T Hoelting ◽  
Q Duh ◽  
O Clark ◽  
C Herfarth
Keyword(s):  
Thyroid Cancer ◽  
Growth Factors ◽  
Proliferation And Invasion

scholarly journals TGF-β1 induces HMGA1 expression: The role of HMGA1 in thyroid cancer proliferation and invasion

2017 ◽  
Vol 50 (5) ◽  
pp. 1567-1578 ◽  
Author(s):  
Jing Zhong ◽  
Chang Liu ◽  
Qing Hai Zhang ◽  
Ling Chen ◽  
Ying-Ying Shen ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Proliferation ◽  
Hmga1 Expression ◽  
Proliferation And Invasion ◽  
Tgf Β1

scholarly journals AUF1 Promotes Proliferation and Invasion of Thyroid Cancer via Downregulation of ZBTB2 and Subsequent TRIM58

2021 ◽  
Vol 11 ◽  
Author(s):  
Xin Du ◽  
Jia-Mei Wang ◽  
Da-Lin Zhang ◽  
Tong Wu ◽  
Xiao-Yan Zeng ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Cells ◽  
Binding Sites ◽  
Critical Role ◽  
Common Type ◽  
Migration And Invasion ◽  
Papillary Thyroid ◽  
Thyroid Cancer Cells ◽  
Proliferation And Invasion

The pathogenesis of papillary thyroid cancer (PTC), the most common type of thyroid cancer, is not yet fully understood. This limits the therapeutic options for approximately 7% of invasive PTC patients. The critical role of AUF1 in the progression of thyroid cancer was first reported in 2009, however, its molecular mechanism remained unclear. Our study used CRISPR/Cas 9 system to knockdown AUF1 in IHH4 and TPC1 cells. We noticed that the expression of TRIM58 and ZBTB2 were increased in the AUF1 knockdown IHH4 and TPC1 cells. When TRIM58 and ZBTB2 were inhibited by small hairpin RNAs (shRNAs) against TRIM58 (shTRIM58) and ZBTB2 (shZBTB2), respectively, the proliferation, migration, and invasion ability of the AUF1-knockdown IHH4 and TPC1 cells were increased. In addition, two ZBTB2 binding sites (-719~-709 and -677~-668) on TRIM58 promoter and two AUF1 binding sites (1250-1256 and 1258-1265) on ZBTB2 3’-UTR were identified. These results suggested that AUF1 affecting thyroid cancer cells via regulating the expression of ZBTB2 and TRIM58.

1386: Role of Seminal Growth Factors in Infertile Men with Varicocele

2004 ◽  
Vol 171 (4S) ◽  
pp. 365-365
Author(s):  
Tamer M. Said ◽  
Shyam Allamaneni ◽  
Kiran P. Nallella ◽  
Rakesh K. Sharma ◽  
Mohamed A. Bedaiwy ◽  
...  
Keyword(s):  
Growth Factors ◽  
Infertile Men

The role of radioiodine SPECT/CT in differentiated thyroid cancer

2013 ◽  
Author(s):  
Emese Mezosi ◽  
Laszlo Bajnok ◽  
Karoly Rucz ◽  
Csaba Weninger ◽  
Erzsebet Schmidt ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer

The role of preoperative serum thyroglobulin values in the diagnosis of differentiated thyroid cancer

2017 ◽  
Author(s):  
Blertina Dyrmishi ◽  
Taulant Olldashi ◽  
Ema Lumi ◽  
Entela Puca ◽  
Dorina Ylli ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Serum Thyroglobulin ◽  
Preoperative Serum
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