scholarly journals Integrated analysis of the differential cellular and EBV miRNA expression profiles in microdissected nasopharyngeal carcinoma and non-cancerous nasopharyngeal tissues

2015 ◽  
Vol 34 (5) ◽  
pp. 2585-2601 ◽  
Author(s):  
XUN-XUN WAN ◽  
HONG YI ◽  
JIA-QUAN QU ◽  
QIU-YAN HE ◽  
ZHI-QIANG XIAO
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Mirna Expression ◽  
Expression Profiles ◽  
Integrated Analysis ◽  
Mirna Expression Profiles

scholarly journals Integrated analysis of mRNA and miRNA expression profiles in pancreatic ductal adenocarcinoma

2017 ◽  
Vol 37 (5) ◽  
pp. 2779-2786 ◽  
Author(s):  
Hongwei Sun ◽  
Liang Zhao ◽  
Kehua Pan ◽  
Zhao Zhang ◽  
Mengtao Zhou ◽  
...  
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Mirna Expression ◽  
Expression Profiles ◽  
Ductal Adenocarcinoma ◽  
Integrated Analysis ◽  
Mirna Expression Profiles

The Predominant microRNAs in β-cell Clusters for Insulin Regulation and Diabetic Control

2020 ◽  
Vol 21 (7) ◽  
pp. 722-734
Author(s):  
Adele Soltani ◽  
Arefeh Jafarian ◽  
Abdolamir Allameh
Keyword(s):  
Mirna Expression ◽  
Expression Profiles ◽  
Expression Patterns ◽  
Diabetic Control ◽  
In Vitro Proliferation ◽  
Cell Functions ◽  
Mirna Expression Profiles ◽  
Multiple Processes ◽  
The Impact

micro (mi)-RNAs are vital regulators of multiple processes including insulin signaling pathways and glucose metabolism. Pancreatic β-cells function is dependent on some miRNAs and their target mRNA, which together form a complex regulative network. Several miRNAs are known to be directly involved in β-cells functions such as insulin expression and secretion. These small RNAs may also play significant roles in the fate of β-cells such as proliferation, differentiation, survival and apoptosis. Among the miRNAs, miR-7, miR-9, miR-375, miR-130 and miR-124 are of particular interest due to being highly expressed in these cells. Under diabetic conditions, although no specific miRNA profile has been noticed, the expression of some miRNAs and their target mRNAs are altered by posttranscriptional mechanisms, exerting diverse signs in the pathobiology of various diabetic complications. The aim of this review article is to discuss miRNAs involved in the process of stem cells differentiation into β-cells, resulting in enhanced β-cell functions with respect to diabetic disorders. This paper will also look into the impact of miRNA expression patterns on in vitro proliferation and differentiation of β-cells. The efficacy of the computational genomics and biochemical analysis to link the changes in miRNA expression profiles of stem cell-derived β-cells to therapeutically relevant outputs will be discussed as well.

scholarly journals miRNA expression profiles in liver grafts of HCV and HIV/HCV infected recipients, six months after liver transplantation

2021 ◽  
Author(s):  
Michela Bulfoni ◽  
Riccardo Pravisani ◽  
Emiliano Dalla ◽  
Daniela Cesselli ◽  
Masaaki Hidaka ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Mirna Expression ◽  
Expression Profiles ◽  
Mirna Expression Profiles

Effects of the Co‐Administration of MK‐801 and Clozapine MiRNA Expression Profiles in Rats

2021 ◽  
Author(s):  
Wenhui Huang ◽  
Xuefeng Gu ◽  
Yingying Wang ◽  
Yuhan Bi ◽  
Yu. Yang ◽  
...  
Keyword(s):  
Mirna Expression ◽  
Expression Profiles ◽  
Mk 801 ◽  
Mirna Expression Profiles
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