Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60 leukemia cells through inhibition of the PI3K-AKT signaling pathway

CHENGJUN HU; MAOZHONG XU; RUJUAN QIN; WEIFENG CHEN; XIN XU

doi:10.3892/or.2015.3896

Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60 leukemia cells through inhibition of the PI3K-AKT signaling pathway

Oncology Reports ◽

10.3892/or.2015.3896 ◽

2015 ◽

Vol 33 (6) ◽

pp. 3146-3154 ◽

Cited By ~ 19

Author(s):

CHENGJUN HU ◽

MAOZHONG XU ◽

RUJUAN QIN ◽

WEIFENG CHEN ◽

XIN XU

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Akt Signaling ◽

Leukemia Cells ◽

Akt Signaling Pathway

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Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway

Toxicology in Vitro ◽

10.1016/j.tiv.2017.03.003 ◽

2017 ◽

Vol 41 ◽

pp. 232-244 ◽

Cited By ~ 31

Author(s):

Yujing Zhang ◽

Fang Xiao ◽

Xinmin Liu ◽

Kaihua Liu ◽

Xiaoxin Zhou ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Mitochondrial Dysfunction ◽

Signaling Pathway ◽

Akt Signaling ◽

Akt Signaling Pathway

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Icariin Inhibits Endoplasmic Reticulum Stress-induced Neuronal Apoptosis after Spinal Cord Injury through Modulating the PI3K/AKT Signaling Pathway

International Journal of Biological Sciences ◽

10.7150/ijbs.30348 ◽

2019 ◽

Vol 15 (2) ◽

pp. 277-286 ◽

Cited By ~ 14

Author(s):

Haotian Li ◽

Xinran Zhang ◽

Xi Qi ◽

Xu Zhu ◽

Liming Cheng

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Neuronal Apoptosis ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Cord Injury

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Inhibition of endoplasmic reticulum stress by intermedin1–53 protects against myocardial injury through a PI3 kinase–Akt signaling pathway

Journal of Molecular Medicine ◽

10.1007/s00109-011-0808-5 ◽

2011 ◽

Vol 89 (12) ◽

pp. 1195-1205 ◽

Cited By ~ 29

Author(s):

Xu Teng ◽

Junqiu Song ◽

Gaigai Zhang ◽

Yan Cai ◽

Fang Yuan ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Myocardial Injury ◽

Akt Signaling ◽

Pi3 Kinase ◽

Akt Signaling Pathway

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Metallothionein prevents intermittent hypoxia-induced cardiac endoplasmic reticulum stress and cell death likely via activation of Akt signaling pathway in mice

Toxicology Letters ◽

10.1016/j.toxlet.2014.03.011 ◽

2014 ◽

Vol 227 (2) ◽

pp. 113-123 ◽

Cited By ~ 26

Author(s):

Shanshan Zhou ◽

Xia Yin ◽

Yang Zheng ◽

Xiao Miao ◽

Wenke Feng ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Cell Death ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Intermittent Hypoxia ◽

Akt Signaling ◽

Akt Signaling Pathway

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Inhibition of Endoplasmic Reticulum Stress Apoptosis by Estrogen Protects Human Umbilical Vein Endothelial Cells Through the PI3 Kinase-Akt Signaling Pathway

Journal of Cellular Biochemistry ◽

10.1002/jcb.26120 ◽

2017 ◽

Vol 118 (12) ◽

pp. 4568-4574 ◽

Cited By ~ 9

Author(s):

Qing Su ◽

Yu Wang ◽

Xin Yang ◽

Xiao-Dong Li ◽

Yong-Fen Qi ◽

...

Keyword(s):

Endothelial Cells ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Umbilical Vein ◽

Akt Signaling ◽

Pi3 Kinase ◽

Akt Signaling Pathway ◽

Human Umbilical Vein ◽

Umbilical Vein Endothelial Cells

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PHLDA3 inhibition attenuates endoplasmic reticulum stress‑induced apoptosis in myocardial hypoxia/reoxygenation injury by activating the PI3K/AKT signaling pathway

Experimental and Therapeutic Medicine ◽

10.3892/etm.2021.10045 ◽

2021 ◽

Vol 21 (6) ◽

Author(s):

Kai Liu ◽

Ying Chen ◽

Fen Ai ◽

Yun-Qian Li ◽

Kun Zhang ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Myocardial Hypoxia ◽

Reoxygenation Injury ◽

Induced Apoptosis ◽

Hypoxia Reoxygenation

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Alpha-Lipoic Acid Inhibits Endoplasmic Reticulum Stress-induced Cell Death Through PI3K/Akt Signaling Pathway in FRTL5 Thyroid Cells

Hormone and Metabolic Research ◽

10.1055/s-0031-1277182 ◽

2011 ◽

Vol 43 (07) ◽

pp. 445-451 ◽

Cited By ~ 9

Author(s):

S. J. Lee ◽

S. H. Kim ◽

J. G. Kang ◽

C. S. Kim ◽

S.-H. Ihm ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Cell Death ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Lipoic Acid ◽

Akt Signaling ◽

Alpha Lipoic Acid ◽

Akt Signaling Pathway ◽

Thyroid Cells

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Effects of endoplasmic reticulum stress on autophagy and apoptosis of human leukemia cells via inhibition of the PI3K/AKT/mTOR signaling pathway

Molecular Medicine Reports ◽

10.3892/mmr.2018.8840 ◽

2018 ◽

Author(s):

Li‑Juan Li ◽

Ye Chai ◽

Xiao‑Jia Guo ◽

Song‑Lin Chu ◽

Lian‑Sheng Zhang

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Mtor Signaling ◽

Leukemia Cells ◽

Human Leukemia ◽

Mtor Signaling Pathway ◽

Human Leukemia Cells

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ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

Biological Research ◽

10.1186/s40659-019-0232-9 ◽

2019 ◽

Vol 52 (1) ◽

Cited By ~ 9

Author(s):

Yubin Feng ◽

Xiaoxiao Hua ◽

Ruowen Niu ◽

Yan Du ◽

Congjian Shi ◽

...

Keyword(s):

Signaling Pathway ◽

Akt Signaling ◽

Leukemia Cells ◽

Akt Signaling Pathway

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Cordycepin induces apoptosis of human acute monocytic leukemia cells via downregulation of the ERK/Akt signaling pathway

Experimental and Therapeutic Medicine ◽

10.3892/etm.2017.4855 ◽

2017 ◽

Vol 14 (4) ◽

pp. 3067-3073 ◽

Cited By ~ 2

Author(s):

Yue Wang ◽

Huimin Mo ◽

Jun Gu ◽

Kan Chen ◽

Zhihua Han ◽

...

Keyword(s):

Signaling Pathway ◽

Akt Signaling ◽

Leukemia Cells ◽

Acute Monocytic Leukemia ◽

Akt Signaling Pathway ◽

Monocytic Leukemia

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