scholarly journals MicroRNA-200 family members and ZEB2 are associated with brain metastasis in gastric adenocarcinoma

2014 ◽  
Vol 45 (6) ◽  
pp. 2403-2410 ◽  
Author(s):  
YANG-KI MINN ◽  
DA HYE LEE ◽  
WOO JIN HYUNG ◽  
JI EUN KIM ◽  
JUNJEONG CHOI ◽  
...  
Keyword(s):  
Brain Metastasis ◽  
Gastric Adenocarcinoma ◽  
Family Members

scholarly journals β-Catenin activation in fundic gland polyps, gastric cancer and colonic polyps in families afflicted by ‘gastric adenocarcinoma and proximal polyposis of the stomach’ (GAPPS)

2016 ◽  
Vol 69 (9) ◽  
pp. 826-833 ◽  
Author(s):  
Lucas A McDuffie ◽  
Arvind Sabesan ◽  
Michael Allgäeuer ◽  
Liqiang Xin ◽  
Christopher Koh ◽  
...  
Keyword(s):  
At Risk ◽  
Gastric Adenocarcinoma ◽  
Family Members ◽  
Colonic Polyps ◽  
Fundic Gland ◽  
Cancer Syndrome ◽  
Clinical Trial Registration ◽  
Gastrointestinal Polyposis ◽  
Colonic Involvement ◽  
Fundic Gland Polyps

AimTo evaluate possible colon involvement in the ‘gastric adenocarcinoma and proximal polyposis of the stomach’ (GAPPS) gastrointestinal polyposis syndrome.MethodsProspective clinicopathological evaluation of two GAPPS families and expression of nuclear β-catenin, p53 and Ki67 measured by immunohistochemistry on endoscopic and surgical specimens from patients with GAPPS.ResultsPatients with the GAPPS phenotype were more frequently affected by colonic polyps than patients at risk within the same families (p<0.01). Colonic polyps shared immunohistochemical features of fundic gland polyps and gastric cancers including increased expression of nuclear β-catenin, Ki67 and p53. Both gastric and colonic lesions harboured activating somatic variants of β-catenin signalling.ConclusionsSimilarities in expression markers in fundic gland and colonic polyps, together with an enrichment of colonic adenomas in family members affected by GAPPS phenotype compared with family members at risk, support mild colonic involvement of this rare cancer syndrome. Colonoscopic screening might be warranted.Clinical Trial Registration Number#09-C-0079; Results.

scholarly journals Effect ofHelicobacter pyloriinfection on expressions of Bcl-2 family members in gastric adenocarcinoma

2004 ◽  
Vol 10 (2) ◽  
pp. 227 ◽  
Author(s):  
Hao Zhang ◽  
Dian-Chun Fang ◽  
Rong-Quan Wang ◽  
Shi-Ming Yang ◽  
Hai-Feng Liu ◽  
...  
Keyword(s):  
Gastric Adenocarcinoma ◽  
Family Members

Effective Clinical Interviewing

1978 ◽  
Vol 9 (4) ◽  
pp. 265-271 ◽  
Author(s):  
Pauline T. Flynn
Keyword(s):  
Family Members ◽  
Essential Elements ◽  
Speech Language Pathologist ◽  
Lay Persons ◽  
Clinical Interviewing ◽  
Client Management

Speech, language, and hearing professionals rely on many individuals to provide information about a client. Management programs, in part, are devised, modified, and evaluated according to responses obtained from the client, family members, educators, and other professional and lay persons who have contact with the client. The speech-language pathologist has the responsibility of obtaining pertinent, complete, unbiased information about clients. This article provides an overview of the essential elements of an interview.

Much Ado About Fried Chicken: Abetting Aspiration or Respecting Autonomy?

2019 ◽  
Vol 28 (3) ◽  
pp. 1356-1362
Author(s):  
Laurence Tan Lean Chin ◽  
Yu Jun Lim ◽  
Wan Ling Choo
Keyword(s):  
Palliative Care ◽  
End Of Life ◽  
Multidisciplinary Team ◽  
Biopsychosocial Model ◽  
Family Members ◽  
Clinical Decisions ◽  
Goals Of Care ◽  
Complex Needs ◽  
Aspiration Risk ◽  
Patient Centric

Purpose Palliative care is a philosophy of care that encompasses holistic, patient-centric care involving patients and their family members and loved ones. Palliative care patients often have complex needs. A common challenge in managing patients near their end of life is the complexity of navigating clinical decisions and finding achievable and realistic goals of care that are in line with the values and wishes of patients. This often results in differing opinions and conflicts within the multidisciplinary team. Conclusion This article describes a tool derived from the biopsychosocial model and the 4-quadrant ethical model. The authors describe the use of this tool in managing a patient who wishes to have fried chicken despite aspiration risk and how this tool was used to encourage discussions and reduce conflict and distress within the multidisciplinary team.

A Strengths-Based Approach to Autism: Neurodiversity and Partnering With the Autism Community

2017 ◽  
Vol 2 (1) ◽  
pp. 56-68 ◽  
Author(s):  
Amy L. Donaldson ◽  
Karen Krejcha ◽  
Andy McMillin
Keyword(s):  
Broad Spectrum ◽  
First Language ◽  
Family Members ◽  
Community Identity ◽  
Speech Language Pathologists

The autism community represents a broad spectrum of individuals, including those experiencing autism, their parents and/or caregivers, friends and family members, professionals serving these individuals, and other allies and advocates. Beliefs, experiences, and values across the community can be quite varied. As such, it is important for the professionals serving the autism community to be well-informed about current discussions occurring within the community related to neurodiversity, a strengths-based approach to partnering with autism community, identity-first language, and concepts such as presumed competence. Given the frequency with which speech-language pathologists (SLPs) serve the autism community, the aim of this article is to introduce and briefly discuss these topics.

Dermatophytes Tracked Among Family Members

2006 ◽  
Vol 39 (23) ◽  
pp. 11
Author(s):  
Timothy F. Kirn
Keyword(s):  
Family Members
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