Valproic acid, an anti-epileptic drug and a histone deacetylase inhibitor, in combination with proteasome inhibitors exerts antiproliferative, pro-apoptotic and chemosensitizing effects in human colorectal cancer cells: Underlying molecular mechanisms

MOHAMED-SALAH I. ABAZA; ABDUL-MAJEED BAHMAN; RAJA’A J. AL-ATTIYAH

doi:10.3892/ijmm.2014.1795

Valproic acid, an anti-epileptic drug and a histone deacetylase inhibitor, in combination with proteasome inhibitors exerts antiproliferative, pro-apoptotic and chemosensitizing effects in human colorectal cancer cells: Underlying molecular mechanisms

International Journal of Molecular Medicine ◽

10.3892/ijmm.2014.1795 ◽

2014 ◽

Vol 34 (2) ◽

pp. 513-532 ◽

Cited By ~ 10

Author(s):

MOHAMED-SALAH I. ABAZA ◽

ABDUL-MAJEED BAHMAN ◽

RAJA’A J. AL-ATTIYAH

Keyword(s):

Colorectal Cancer ◽

Valproic Acid ◽

Histone Deacetylase Inhibitor ◽

Molecular Mechanisms ◽

Proteasome Inhibitors ◽

Human Colorectal Cancer ◽

Anti Epileptic Drug ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Superior antimitogenic and chemosensitization activities of the combination treatment of the histone deacetylase inhibitor apicidin and proteasome inhibitors on human colorectal cancer cells

International Journal of Oncology ◽

10.3892/ijo.2013.2146 ◽

2013 ◽

Vol 44 (1) ◽

pp. 105-128 ◽

Cited By ~ 7

Author(s):

MOHAMED-SALAH I. ABAZA ◽

ABDUL-MAJEED BAHMAN ◽

RAJA’A AL-ATTIYAH

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Combination Treatment ◽

Histone Deacetylase Inhibitor ◽

Proteasome Inhibitors ◽

Human Colorectal Cancer ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Synergistic induction of apoptosis and chemosensitization of human colorectal cancer cells by histone deacetylase inhibitor, scriptaid, and proteasome inhibitors: potential mechanisms of action

Tumor Biology ◽

10.1007/s13277-012-0456-6 ◽

2012 ◽

Vol 33 (6) ◽

pp. 1951-1972 ◽

Cited By ~ 12

Author(s):

M. S. I. Abaza ◽

A. M. Bahman ◽

R. J. Al-Attiyah ◽

A. M. Kollamparambil

Keyword(s):

Colorectal Cancer ◽

Histone Deacetylase Inhibitor ◽

Proteasome Inhibitors ◽

Mechanisms Of Action ◽

Human Colorectal Cancer ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Synergistic Induction ◽

Induction Of Apoptosis ◽

Human Colorectal Cancer Cells

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Superior antiproliferative activity of histone deacetylase inhibitor apicidin and proteasome inhibitors against human colorectal cancer cells

The FASEB Journal ◽

10.1096/fasebj.24.1_supplement.964.4 ◽

2010 ◽

Vol 24 (S1) ◽

Author(s):

Mohamed Salah Abaza ◽

Abdul‐Majeed Bahman ◽

Rajaa Al‐Attiyah

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Antiproliferative Activity ◽

Histone Deacetylase Inhibitor ◽

Proteasome Inhibitors ◽

Human Colorectal Cancer ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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A novel class I histone deacetylase inhibitor, I-7ab, induces apoptosis and arrests cell cycle progression in human colorectal cancer cells

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2015.02.019 ◽

2015 ◽

Vol 71 ◽

pp. 70-78 ◽

Cited By ~ 13

Author(s):

Liyan Yang ◽

Qiannan Liang ◽

Ke Shen ◽

Li Ma ◽

Na An ◽

...

Keyword(s):

Colorectal Cancer ◽

Cell Cycle ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Cell Cycle Progression ◽

Human Colorectal Cancer ◽

Cycle Progression ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells

Molecular Carcinogenesis ◽

10.1002/mc.20777 ◽

2011 ◽

Vol 51 (2) ◽

pp. 174-184 ◽

Cited By ~ 64

Author(s):

Hua Xiong ◽

Wan Du ◽

Yan-Jie Zhang ◽

Jie Hong ◽

Wen-Yu Su ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Human Colorectal Cancer ◽

Stat3 Signaling ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Synergistic interaction between scriptaid and proteasome inhibitors enhances the sensitivity of human colorectal cancer cells to chemotherapeutic drugs

The FASEB Journal ◽

10.1096/fasebj.26.1_supplement.1038.1 ◽

2012 ◽

Vol 26 (S1) ◽

Author(s):

Mohamed Salah Abaza ◽

Abdul-Majeed Bahman ◽

Rajaa Al-Attiyah

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Proteasome Inhibitors ◽

Synergistic Interaction ◽

Chemotherapeutic Drugs ◽

Human Colorectal Cancer ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Ferulic Acid Methylester from Tamarix aucheriana , Shows Anticancer Activity against Human Colorectal Cancer Cells: Underlying Molecular Mechanisms

The FASEB Journal ◽

10.1096/fasebj.29.1_supplement.936.10 ◽

2015 ◽

Vol 29 (S1) ◽

Author(s):

Mohamed Abaza ◽

Mohammad Afzal ◽

Rajaa Al‐Attiyah ◽

Radhika Guleri

Keyword(s):

Colorectal Cancer ◽

Ferulic Acid ◽

Anticancer Activity ◽

Cancer Cells ◽

Molecular Mechanisms ◽

Human Colorectal Cancer ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide in human colorectal cancer cells in vitro and in vivo

Oncotarget ◽

10.18632/oncotarget.5475 ◽

2015 ◽

Vol 6 (34) ◽

pp. 35991-36002 ◽

Cited By ~ 4

Author(s):

Chun-Han Chen ◽

Chia-Hwa Lee ◽

Jing-Ping Liou ◽

Che-Ming Teng ◽

Shiow-Lin Pan

Keyword(s):

Colorectal Cancer ◽

Antitumor Activity ◽

Cancer Cells ◽

Molecular Mechanisms ◽

Human Colorectal Cancer ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Augmentation of the anticancer effects of proteasome inhibitors by combination with sodium butyrate in human colorectal cancer cells

Experimental and Therapeutic Medicine ◽

10.3892/etm_00000106 ◽

2010 ◽

Vol 1 (4) ◽

pp. 675-693 ◽

Cited By ~ 8

Author(s):

M.S.I. ABAZA

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Sodium Butyrate ◽

Proteasome Inhibitors ◽

Human Colorectal Cancer ◽

Anticancer Effects ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Molecular mechanisms of antitumor activity of the polymeric form of niclosamide with respect to human colorectal cancer cells

Biochemistry (Moscow) Supplement Series B Biomedical Chemistry ◽

10.1134/s1990750817030131 ◽

2017 ◽

Vol 11 (3) ◽

pp. 301-307 ◽

Cited By ~ 1

Author(s):

A. S. Zhirnik ◽

Yu. P. Semochkina ◽

E. Yu. Moskaleva ◽

N. I. Krylov ◽

I. A. Tubasheva ◽

...

Keyword(s):

Colorectal Cancer ◽

Antitumor Activity ◽

Cancer Cells ◽

Molecular Mechanisms ◽

Human Colorectal Cancer ◽

Polymeric Form ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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