Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1
 and SOCS3
 in human colorectal cancer cells

Hua Xiong; Wan Du; Yan-Jie Zhang; Jie Hong; Wen-Yu Su; Jie-Ting Tang; Ying-Chao Wang; Rong Lu; Jing-Yuan Fang

doi:10.1002/mc.20777

Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells

Molecular Carcinogenesis ◽

10.1002/mc.20777 ◽

2011 ◽

Vol 51 (2) ◽

pp. 174-184 ◽

Cited By ~ 64

Author(s):

Hua Xiong ◽

Wan Du ◽

Yan-Jie Zhang ◽

Jie Hong ◽

Wen-Yu Su ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Human Colorectal Cancer ◽

Stat3 Signaling ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Superior antimitogenic and chemosensitization activities of the combination treatment of the histone deacetylase inhibitor apicidin and proteasome inhibitors on human colorectal cancer cells

International Journal of Oncology ◽

10.3892/ijo.2013.2146 ◽

2013 ◽

Vol 44 (1) ◽

pp. 105-128 ◽

Cited By ~ 7

Author(s):

MOHAMED-SALAH I. ABAZA ◽

ABDUL-MAJEED BAHMAN ◽

RAJA’A AL-ATTIYAH

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Combination Treatment ◽

Histone Deacetylase Inhibitor ◽

Proteasome Inhibitors ◽

Human Colorectal Cancer ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Superior antiproliferative activity of histone deacetylase inhibitor apicidin and proteasome inhibitors against human colorectal cancer cells

The FASEB Journal ◽

10.1096/fasebj.24.1_supplement.964.4 ◽

2010 ◽

Vol 24 (S1) ◽

Author(s):

Mohamed Salah Abaza ◽

Abdul‐Majeed Bahman ◽

Rajaa Al‐Attiyah

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Antiproliferative Activity ◽

Histone Deacetylase Inhibitor ◽

Proteasome Inhibitors ◽

Human Colorectal Cancer ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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The histone deacetylase inhibitor trichostatin A induces cell cycle arrest and apoptosis in colorectal cancer cells via p53-dependent and -independent pathways

Oncology Reports ◽

10.3892/or.2012.1793 ◽

2012 ◽

Author(s):

Qi-Bing Mei

Keyword(s):

Colorectal Cancer ◽

Cell Cycle ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Cycle Arrest ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Histone Deacetylase Inhibitor Trichostatin

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A novel class I histone deacetylase inhibitor, I-7ab, induces apoptosis and arrests cell cycle progression in human colorectal cancer cells

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2015.02.019 ◽

2015 ◽

Vol 71 ◽

pp. 70-78 ◽

Cited By ~ 13

Author(s):

Liyan Yang ◽

Qiannan Liang ◽

Ke Shen ◽

Li Ma ◽

Na An ◽

...

Keyword(s):

Colorectal Cancer ◽

Cell Cycle ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Cell Cycle Progression ◽

Human Colorectal Cancer ◽

Cycle Progression ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Growth arrest, apoptosis and potentiation of 5-fluorouracil and Raltitrexed cytotoxic effect induced by histone deacetylase inhibitor SAHA in colorectal cancer cells

European Journal of Cancer ◽

10.1016/s0959-8049(02)80730-4 ◽

2002 ◽

Vol 38 ◽

pp. S29

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Cytotoxic Effect ◽

Growth Arrest ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells

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Ailanthone suppresses the activity of human colorectal cancer cells through the STAT3 signaling pathway

International Journal of Molecular Medicine ◽

10.3892/ijmm.2021.5076 ◽

2021 ◽

Vol 49 (2) ◽

Author(s):

Haixiang Ding ◽

Xiuchong Yu ◽

Zhilong Yan

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Human Colorectal Cancer ◽

Stat3 Signaling ◽

Stat3 Signaling Pathway ◽

Colorectal Cancer Cells ◽

Human Colorectal Cancer Cells

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Structure-activity relationship of butyrate analogues on apoptosis, proliferation and histone deacetylase activity in HCT-116 human colorectal cancer cells

Clinical and Experimental Pharmacology and Physiology ◽

10.1111/j.1440-1681.2010.05403.x ◽

2010 ◽

Vol 37 (9) ◽

pp. 905-911 ◽

Cited By ~ 10

Author(s):

Cheng Cheng Ooi ◽

Norm M Good ◽

Desmond B Williams ◽

Tanya Lewanowitsch ◽

Leah J Cosgrove ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Activity Relationship ◽

Human Colorectal Cancer ◽

Structure Activity ◽

Colorectal Cancer Cells ◽

Hct 116 ◽

Relationship Of ◽

Human Colorectal Cancer Cells

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Sesamolin exerts anti-proliferative and apoptotic effect on human colorectal cancer cells via inhibition of JAK2/STAT3 signaling pathway

Cellular and Molecular Biology ◽

10.14715/cmb/2019.65.6.16 ◽

2019 ◽

Vol 65 (6) ◽

pp. 96

Author(s):

Di Wu ◽

Xin-Ping Wang ◽

Wei Zhang

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Human Colorectal Cancer ◽

Stat3 Signaling ◽

Stat3 Signaling Pathway ◽

Colorectal Cancer Cells ◽

Apoptotic Effect ◽

Human Colorectal Cancer Cells

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Synergistic induction of apoptosis and chemosensitization of human colorectal cancer cells by histone deacetylase inhibitor, scriptaid, and proteasome inhibitors: potential mechanisms of action

Tumor Biology ◽

10.1007/s13277-012-0456-6 ◽

2012 ◽

Vol 33 (6) ◽

pp. 1951-1972 ◽

Cited By ~ 12

Author(s):

M. S. I. Abaza ◽

A. M. Bahman ◽

R. J. Al-Attiyah ◽

A. M. Kollamparambil

Keyword(s):

Colorectal Cancer ◽

Histone Deacetylase Inhibitor ◽

Proteasome Inhibitors ◽

Mechanisms Of Action ◽

Human Colorectal Cancer ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells ◽

Synergistic Induction ◽

Induction Of Apoptosis ◽

Human Colorectal Cancer Cells

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Histone deacetylase inhibitor valproic acid (VPA) promotes the epithelial mesenchymal transition of colorectal cancer cells via up regulation of Snail

Cell Adhesion & Migration ◽

10.1080/19336918.2015.1112486 ◽

2015 ◽

Vol 9 (6) ◽

pp. 495-501 ◽

Cited By ~ 30

Author(s):

Jutao Feng ◽

Junhua Cen ◽

Jun Li ◽

Rujin Zhao ◽

Canhua Zhu ◽

...

Keyword(s):

Colorectal Cancer ◽

Valproic Acid ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Epithelial Mesenchymal Transition ◽

Mesenchymal Transition ◽

Deacetylase Inhibitor ◽

Colorectal Cancer Cells

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