scholarly journals Effect of transoral endoscopic adenoidectomy on peripheral blood T-lymphocyte subsets in children with obstructive sleep apnea-hypopnea syndrome and its treatment strategy

2017 ◽  
Vol 14 (4) ◽  
pp. 3022-3028 ◽  
Author(s):  
Na Yang ◽  
Yaofeng Ji ◽  
Yin Liu
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
T Lymphocyte ◽  
Treatment Strategy ◽  
Peripheral Blood ◽  
Lymphocyte Subsets ◽  
T Lymphocyte Subsets ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

scholarly journals CD4+T-lymphocyte subsets in nonobese children with obstructive sleep apnea syndrome

2015 ◽  
Vol 78 (2) ◽  
pp. 165-173 ◽  
Author(s):  
Jin Ye ◽  
Hui Liu ◽  
Peng Li ◽  
Zhuang-gui Chen ◽  
Ge-hua Zhang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
T Lymphocyte ◽  
Lymphocyte Subsets ◽  
Sleep Apnea Syndrome ◽  
T Lymphocyte Subsets ◽  
Obstructive Sleep ◽  
Apnea Syndrome

scholarly journals The Impact of Obstructive Sleep Apnea-Hypopnea Syndrome on T-Lymphocyte Subgroups and Natural Killer Cell Activity in the Peripheral Blood of Children

2020 ◽  
Vol 30 (6) ◽  
Author(s):  
Lili Huang ◽  
Yimin Chen ◽  
Jiarong Wang ◽  
Liansheng Qiu
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
T Lymphocyte ◽  
Cellular Immunity ◽  
Peripheral Blood ◽  
Nk Cell ◽  
Cell Activity ◽  
Nk Cell Activity ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

Background: Obstructive sleep apnea-hypopnea syndrome (OSAHS) can impact multiple organ systems in children. Objectives: To investigate the effects of OSAHS on T-lymphocyte subgroups and natural killer (NK) cell activity in the peripheral blood of affected children. Methods: A total of 85 children with OSAHS were enrolled into an experimental group (OSAHS) and 76 healthy children were placed in a control group (CON) to compare peripheral blood levels of CD3+, CD4+, CD8+, and NK cell activity using flow cytometry. Meanwhile, their polysomnography results were monitored to analyze the correlation between T-lymphocyte subgroups/NK cell activity and lowest pulse oxygen saturation (LSaO2)/apnea-hypopnea index (AHI). Results: Compared to the CON group, the CD3+ percentage in the OSAHS group showed no significant difference (65.98 ± 6.54 vs 64.36 ± 5.32; P > 0.05), but the CD4+ percentage, CD4+/CD8+ ratio, and NK cell activity decreased markedly (33.52 ± 3.04 vs 35.26 ± 3.68,1.29 ± 0.14 vs 1.43 ± 0.26, and 11.47 ± 4.58 vs 12.69 ± 2.36, respectively; P < 0.05). In addition, the CD8+ percentage increased significantly (26.18 ± 4.76 vs 24.36 ± 2.32; P < 0.05). Linear regression analysis indicated that the CD3+ percentage was not related to LSaO2/AHI (P > 0.05), but the CD4+ and CD8+ percentages, CD4+/CD8+ ratio, and NK cell activity were linearly related to LSaO2 and AHI (P < 0.05). Conclusions: OSAHS can affect the cellular immunity of children. The AHI and LSaO2 may be involved in cellular immunity function.

scholarly journals OSAHS in adolescents: clinical presentation and differential diagnosis

2018 ◽  
Vol 21 (1) ◽  
pp. 106
Author(s):  
N. Beydon
Keyword(s):  
Obstructive Sleep Apnea ◽  
Differential Diagnosis ◽  
Sleep Apnea ◽  
Clinical Presentation ◽  
Transitional Period ◽  
Alternative Diagnosis ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

Adolescent experiment widespread changes as he/ she goes through this transitional period from childhood to adulthood. Sleep is no exception to this changeover with, as consequences, modifications of the clinical pre- sentation of subjects with Obstructive Sleep Apnea- Hypopnea Syndrome (OSAHS) and potential different alternative diagnosis.

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